The evaluation of the efficacy and safety about apatinib combined with immune checkpoint inhibitors in advanced gastric cancer: a real-world study [0.03%]
阿帕替尼联合免疫检查点抑制剂治疗晚期胃癌的疗效和安全性分析：真实世界研究
Peng-Fei Zhu,Liu Yang,Zhe-Ling Chen
Peng-Fei Zhu
Background: Apatinib and immune checkpoint inhibitors (ICIs) have shown promise as third-line treatments for advanced gastric cancer (AGC). This study compared the efficacy and safety of apatinib combined with ICIs versus...
Case report and literature analysis of ectopic gastric glands combined with intestinal-type gastric cancer in an HP-negative background [0.03%]
Shiyu Peng,Shuxin Tian
Shiyu Peng
We report a rare case of intestinal-type gastric cancer combined with submucosal ectopic gastric glands in a patient without Helicobacter pylori (HP) infection. A 55-year-old female presented for a routine health check-up. Gastroscopy revea...
A case report of a rare intrahepatic cholangiocarcinoma with rectal metastasis [0.03%]
一例罕见肝内胆管癌合并结肠转移病例报告
Shu-Min Jiang,Lu Huang,Quan Jiang
Shu-Min Jiang
Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer with insidious onset, rapid progression, and poor prognosis. The lymphatic system is the main route of ICC distant metastasis, with lungs, adrenal glands, and brain as the most...
Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients [0.03%]
用于评估奥拉帕利治疗铂敏感复发性卵巢癌患者的影像学检查方法
Maria Delgado-Ortet,Vlad Bura,Ionut-Gabriel Funingana et al.
Maria Delgado-Ortet et al.
Background: High-grade serous carcinoma is a highly metastatic disease with a limited longterm disease control from systemic anti-cancer treatment, for which the radiological treatment response assessment metrics are impr...
Sugemalimab plus chemotherapy vs. chemotherapy for treatment of Chinese patients with esophageal squamous cell carcinoma: a cost effectiveness analysis to inform decision making [0.03%]
舒格利单抗联合化疗对比单纯化疗治疗中国食管鳞癌患者的成本效益分析：辅助决策研究
Qiuping Chen,Quan Sun,Baixue Li
Qiuping Chen
Background: The GEMSTONE-304 trial established the clinical benefits of sugemalimab plus chemotherapy in advanced esophageal squamous-cell carcinoma (ESCC). This study evaluates the cost-effectiveness of this regimen vers...
CircRNA: the potential biomarkers and therapeutic targets in oral squamous cell carcinoma (OSCC) [0.03%]
circRNA：口腔鳞状细胞癌（OSCC）中的潜在生物标志物和治疗靶点
Jun-Lin Lv,Ru Ma,Yu-Shan Ren et al.
Jun-Lin Lv et al.
Circular RNAs (circRNAs) are a new category of non-coding RNAs implicated in the molecular pathology of cancer, such as oral squamous cell carcinoma (OSCC). Circular intronic RNAs (ciRNAs), exonic circRNAs (ecircRNAs), and exon-intron circR...
Real-world treatment patterns and survival outcomes in patients with locally advanced squamous cell carcinoma of the head and neck in Germany using claims data [0.03%]
基于保险理赔资料的德国局部晚期头颈部鳞状细胞癌患者的实际治疗模式和生存结果分析
Kathrin Hering,Thomas Kuhnt,Nils Kossack et al.
Kathrin Hering et al.
Introduction: Standard-of-care treatment for locally advanced squamous cell carcinoma of the head and neck (LA SCCHN) is surgery with consolidation chemoradiotherapy (CRT) or definitive CRT. There is a paucity of real-wor...
EPHX2 overexpression deters the advancement of clear cell renal cell carcinoma via lipid metabolism reprogramming [0.03%]
EPHX2过表达通过脂质代谢重编程抑制透明细胞肾细胞癌的发展进展
Bo Guan,Cong Huang,Jun He et al.
Bo Guan et al.
Background: Clear cell renal cell carcinoma (ccRCC) is a prevalent and highly aggressive subtype of renal cancer. EPHX2, a metabolic regulator with tumor-suppressive properties, not only influences cell cycle dynamics but...
Ultrasonography diagnosis of dumbbell-shaped C5 cervical schwannoma: a case report and literature review [0.03%]
哑铃形C5神经鞘瘤的超声诊断一例及文献复习
Kailin Yu,Jingsen Chen,Minqiang Pan et al.
Kailin Yu et al.
Introduction and importance: Dumbbell-shaped C5 schwannomas are rare lesions that involve both intraspinal and extra-spinal communicating compartments. Early diagnosis and complete resection are of great significance in t...
Predicting overall survival benefit in previously untreated, unresectable or metastatic melanoma from improvement in progression-free survival: a correlation meta-analysis [0.03%]
一项相关性meta分析：以前未经治疗、不可切除或转移黑色素瘤的无进展生存期改善与整体生存期获益预测的关系
Peter Mohr,Murat Kurt,Swetha Srinivasan et al.
Peter Mohr et al.
Objectives: To evaluate the association between the treatment effects on progression-free survival (PFS) and overall survival (OS) for previously untreated, unresectable or metastatic melanoma. ...