Development and Diagnostic Validation of an Automated Rapid Testing Platform for Serum Lysophosphatidylcholine as a Sepsis Biomarker [0.03%]
用于血清溶血磷脂酰胆碱脓毒症生物标志物的全自动快速检测平台的开发和诊断验证
Hyeon Kyu Choi,Hyesoo Kim,Mi Hwa Shin et al.
Hyeon Kyu Choi et al.
Background: Sepsis is a life-threatening condition, requiring timely diagnosis and reliable biomarkers for effective management. Lysophosphatidylcholine (LPC) has emerged as a promising biomarker; however, conventional qu...
First Report of KPC-2-Producing Hafnia paralvei: Evidence of Horizontal Gene Transfer from Klebsiella pneumoniae [0.03%]
第一个产生KPC-2的产碱枸掾微菌报告：来自肺炎克雷伯氏菌的基因水平转移证据
Sun-Mi Cho,Myung Seo Kang,Seong Geun Hong
Sun-Mi Cho
Progressive Decline in Interferon-γ Release is Associated with Cirrhosis Progression and Severity: A Prospective Preliminary Report [0.03%]
干扰素-γ释放量的逐渐下降与肝硬化的进展和严重程度有关：一项初步的前瞻性研究报告
Marie-Charlotte Delignette,Muzhda Haem Rahimi,Morgane Gossez et al.
Marie-Charlotte Delignette et al.
Cirrhosis progresses through distinct stages, with increasing severity and susceptibility to infections due to cirrhosis-associated immune dysfunction. Lymphocyte-based functional assays are considered the gold standard for assessing immune...
A Novel ABO*O.01.02-B.01 Hybrid Allele with a c.28+1G>A Variation Causing the Bel Phenotype [0.03%]
一种新的ABO*O.01.02-B.01杂合基因型导致Bel表型的c.28+1G>A变异
Lin-Nan Shao,Chun-Xiang Li,Yue-Xin Xia et al.
Lin-Nan Shao et al.
First Report of Concurrent Infective Endocarditis and Spondylitis Caused by Lactococcus petauri [0.03%]
小棕鼠乳酒状酵母引起的心内膜炎并发脊柱炎首位报告
Kyeong Seon Ryu,Taek Soo Kim,Sue Shin et al.
Kyeong Seon Ryu et al.
Monthly Biological Variation of Five Lung Cancer Markers in Healthy Older Individuals: Evidence from Combined Prospective Cohort and Real-World Data Analyses [0.03%]
健康老年人五种肺癌标志物的月度生物变异性：来自前瞻性队列研究和真实世界数据分析的证据
Ziyang Han,Dan Yang,Hongyi Wang et al.
Ziyang Han et al.
Background: Elderly populations face disproportionate lung cancer burdens; however, biological variation (BV) data for key tumor markers (carcinoma embryonic antigen [CEA], neuron-specific enolase [NSE], cytokeratin 19 fr...
Assessment of a High-resolution HPLC System to Quantify HbE for α0-Thalassemia Diagnosis in HbE Heterozygotes [0.03%]
高分辨率HPLC系统量化HbE以诊断HbE杂合子α0-地中海贫血的评估
Wibhasiri Srisuwan,Surada Satthakarn,Sitthichai Panyasai
Wibhasiri Srisuwan
Background: HbE and α0-thalassemia are highly prevalent in Southeast Asia and co-inherited in asymptomatic carriers. α0-Thalassemia screening in HbE heterozygotes relies on HbE quantification. We evaluated the performan...
Non-specific Clones Hamper the Reliability of Ig Light Chain Gene Rearrangements in Next-Generation Sequencing-Based Measurable Residual Disease Monitoring in Pediatric B-Cell ALL: A Single-Center Cohort Study [0.03%]
基于二代测序的B细胞急性淋巴细胞白血病微小残留病监测中非特异性克隆影响Ig轻链基因重排可靠性的单中心队列研究
Haipin Chen,Jing Miao,Linyang Fan et al.
Haipin Chen et al.
Background: Measurable residual disease (MRD) in B-cell ALL (B-ALL) can be detected via next-generation sequencing (NGS) of Ig gene rearrangements, particularly in Ig heavy chain (IGH) genes. Ig light chain rearrangements...
Performance Evaluation of PacBio PureTarget for Multiple Short Tandem Repeat Expansion Detection [0.03%]
PacBio PureTarget多重短串联重复序列扩张检测的性能评估
Eunju Yeom,Yu Jin Park,Saeam Shin et al.
Eunju Yeom et al.
Background: Excessive repeat sequence expansion in the human genome causes neurodegenerative diseases. Conventional tandem repeat expansion detection methods often fail to amplify GC-rich repeat regions and cannot help in...
Evaluating a Flexible Workflow for Candida auris Surveillance on the AltoStar Automation System AM16 with Commercial and In-House Real-Time PCR Assays [0.03%]
评估阿尔托星自动化系统AM16上用于白色念珠菌监测的灵活工作流程（使用商业和实验室自制实时PCR检测）
Chun Kiat Lee,Janet Weng Sze Cheng,Nur Atiqah Liyana et al.
Chun Kiat Lee et al.
Background: Multidrug-resistant yeast Candida (Candidozyma) auris, responsible for healthcare-associated outbreaks and high mortality, is a major global health threat. Rapid and scalable molecular diagnostics is essential...