Dae-Won Kim,Won Gi Yoo,Hyun Chul Park et al.
Dae-Won Kim et al.
DNA barcoding has been widely used in species identification and biodiversity research. A short fragment of the mitochondrial cytochrome c oxidase subunit I (COI) sequence serves as a DNA bio-barcode. We collected DNA barcodes, based on COI...
Comparison of SNP variation and distribution in indigenous ethiopian and korean cattle (hanwoo) populations [0.03%]
非洲埃塞俄比亚与亚洲韩国（韩牛）本地黄牛SNP多态性及分布的比较分析研究
Zewdu Edea,Hailu Dadi,Sang Wook Kim et al.
Zewdu Edea et al.
Although a large number of single nucleotide polymorphisms (SNPs) have been identified from the bovine genome-sequencing project, few of these have been validated at large in Bos indicus breeds. We have genotyped 192 animals, representing 5...
Effect of Combining Multiple CNV Defining Algorithms on the Reliability of CNV Calls from SNP Genotyping Data [0.03%]
联合应用多种拷贝数定义算法对SNP基因分型数据中检测拷贝数变异的影响研究
Soon-Young Kim,Ji-Hong Kim,Yeun-Jun Chung
Soon-Young Kim
In addition to single-nucleotide polymorphisms (SNP), copy number variation (CNV) is a major component of human genetic diversity. Among many whole-genome analysis platforms, SNP arrays have been commonly used for genomewide CNV discovery. ...
Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans [0.03%]
叶酸代谢通路基因单核苷酸多态性与胃癌关联的病例对照研究（韩国人）
Jae-Young Yoo,Sook-Young Kim,Jung-Ah Hwang et al.
Jae-Young Yoo et al.
Gastric cancer is ranked as the most common cancer in Koreans. A recent molecular biological study about the folate pathway gene revealed the correlation with a couple of cancer types. In the folate pathway, several genes are involved, incl...
Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II) [0.03%]
韩国癌症预防研究二期(KCPS-II)中遗传风险评分对结直肠癌发病风险预测的作用
Jaeseong Jo,Chung Mo Nam,Jae Woong Sull et al.
Jaeseong Jo et al.
Colorectal cancer (CRC) is among the leading causes of cancer deaths and can be caused by environmental factors as well as genetic factors. Therefore, we developed a prediction model of CRC using genetic risk scores (GRS) and evaluated the ...
Discovery and Evaluation of Polymorphisms in the AKT2 and AKT3 Promoter Regions for Risk of Korean Lung Cancer [0.03%]
韩国肺癌风险的AKT2和AKT3启动子区域多态性的发现与评估
Jae Sook Sung,Kyong Hwa Park,Seung Tae Kim et al.
Jae Sook Sung et al.
AKT is a signal transduction protein that plays a central role in the tumorigenesis. There are 3 mammalian isoforms of this serine/threonine protein kinase-AKT1, AKT2, and AKT3-showing a broad tissue distribution. We first discovered 2 nove...
Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling [0.03%]
系统生物学方法揭示TLR和G蛋白偶联受体信号通路之间的非加性响应及多种串扰机制
Jayalakshmi Krishnan,Sangdun Choi
Jayalakshmi Krishnan
A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of pathogens and lead to p...
Characterization of Chromatin Structure-associated Histone Modifications in Breast Cancer Cells [0.03%]
乳腺癌细胞染色质结构相关组蛋白修饰的特征分析
Chang Pyo Hong,Moon Kyung Choe,Tae-Young Roh
Chang Pyo Hong
Chromatin structure and dynamics that are influenced by epigenetic marks, such as histone modification and DNA methylation, play a crucial role in modulating gene transcription. To understand the relationship between histone modifications a...
Shuhua Xu
Shuhua Xu
Genetic admixture in human, the result of inter-marriage among people from different well-differentiated populations, has been extensively studied in the New World, where European colonization brought contact between peoples of Europe, Afri...
Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors [0.03%]
组胺受体激动剂和拮抗剂分子振动频率模式的特征研究
S June Oh
S June Oh
To learn the differences between the structure-activity relationship and molecular vibration-activity relationship in the ligand-receptor interaction of the histamine receptor, 47 ligands of the histamine receptor were analyzed by structura...