Development of lyophilization cycle and effect of excipients on the stability of catalase during lyophilization [0.03%]
冷冻干燥工艺的开发及冻干过程中辅料对过氧化氢酶稳定性的影响
Shantanu V Lale,Monu Goyal,Arvind K Bansal
Shantanu V Lale
Introduction: The purpose of the present study was to screen excipients such as amino acids and non-aqueous solvents for their stabilizing effect on catalase, a model protein, for lyophilization. The present study also in...
Statistical optimization of floating pulsatile drug delivery system for chronotherapy of hypertension [0.03%]
统计优化浮动脉冲给药系统以实现高血压的时辰治疗
Sanjay J Kshirsagar,Shrikant V Patil,Mangesh R Bhalekar
Sanjay J Kshirsagar
Introduction: A pulsatile drug delivery system is characterized by a lag time that is an interval of no drug release followed by rapid drug release. The purpose of this work was to develop hollow calcium alginate beads fo...
Sagar Makwana,Biswajit Basu,Yogita Makasana et al.
Sagar Makwana et al.
Parenteral administration of pharmaceutical products is one of the most popular methods used to produce quick onset of action and also 100% bioavailability. Main problem occurs with the parenteral drug delivery is lack of convenience, affor...
Scope of nano ophthalmology [0.03%]
纳米眼科学的范畴
Javed Ali
Javed Ali
Lallemantia reylenne seeds as superdisintegrant: Formulation and evaluation of nimesulide orodispersible tablets [0.03%]
莱亚门蒂亚雷伊伦尼种子作为超级崩解剂：尼美舒利口服速崩片的制备及评价
Karan Malik,Gurpreet Arora,Inderbir Singh et al.
Karan Malik et al.
Aim: Orodispersible tablets also known as fast dissolving tablets disintegrate instantaneously within the mouth and thus can be consumed without water. The present study was aimed to formulate orodispersible tablets of ni...
Formulation and evaluation of bucco-adhesive tablets of sumatriptan succinate [0.03%]
盐酸舒马普坦口颊溶膜的制备及评价研究
R Indira Prasanna,P Anitha,C Madhusudhana Chetty
R Indira Prasanna
Background: A novel aspiration in treatment of migraine, to provide greater therapeutic effect, overcome the side effects by complex therapeutic regimen and to improve patient compliance upon administering bucco-adhesive ...
Design and evaluation of colon targeted modified pulsincap delivery of 5-fluorouracil according to circadian rhythm [0.03%]
基于生物节律的5-氟尿嘧啶脉动控释胶囊结肠定位给药系统的制剂学研究及评价
Dasharath M Patel,Rushiraj H Jani,Chhagan N Patel
Dasharath M Patel
Introduction: A modified pulsincap dosage form of 5-fluorouracil was developed to target drug to colorectal carcinoma according to daily oscillations of rate-limiting metabolizing enzyme dihydropyrimidine dehydrogenase. ...
In vitro and in vivo evaluation of chitosan buccal films of ondansetron hydrochloride [0.03%]
奥丹司琼盐酸盐壳聚糖颊黏膜给药系统体内外评价研究
Marina Koland,R Narayana Charyulu,K Vijayanarayana et al.
Marina Koland et al.
Buccal films of ondanstron hydrochloride were fabricated from mucoadhesive polymer, chitosan, and polyvinyl pyrrolidone (PVP K30) for the purpose of prolonging drug release and improving its bioavailability. All fabricated film formulations...
Study on sustained-release metformin hydrochloride from matrix tablet: Influence of hydrophilic polymers and in vitro evaluation [0.03%]
羟丙甲纤维素为基质的缓释盐酸二甲双胍片处方及体外评价研究
Kamlesh J Wadher,Rajendra B Kakde,Milind J Umekar
Kamlesh J Wadher
The overall objective of the present work was to develop an oral sustained-release (SR) metformin tablet prepared by the direct compression method, using hydrophilic hydroxylpropylmethylcellulose (HPMC) and Guar gum polymer alone and in com...
Formulation and evaluation of sustained release bioadhesive tablets of ofloxacin using 3(2) factorial design [0.03%]
采用3(2)因子设计制备并评价生物粘附性氟喹酸缓释片剂
Hemant H Gangurde,Mayur A Chordiya,S Tamizharasi et al.
Hemant H Gangurde et al.
Background: Oral sustained release gastroretentive dosage forms offer many advantages for drugs having absorption from upper gastrointestinal tract and improve the bioavailability of medications that are characterized by ...