Thomas Damsin,Gilles Absil,Florence Libon et al.
Thomas Damsin et al.
Background: Biological therapies, including TNF-alpha, IL12/23, IL17 and IL23 antagonists, adequately control a very high number of patients with moderate-to-severe psoriasis with an excellent long-term safety profile. Ho...
Lu Wei,Buxin Zhang,Yuanhui Tu et al.
Lu Wei et al.
Psoriasis is a chronic inflammatory disease with a complex pathogenesis. Hyperplasia of glycolytic-dependent epidermal keratinocytes (KCs) is a new hallmark of psoriasis pathogenesis. Meanwhile, immune cells undergo metabolic reprogramming ...
Unveiling Novel Protein Biomarkers for Psoriasis Through Integrated Analysis of Human Plasma Proteomics and Mendelian Randomization [0.03%]
通过整合人类血浆蛋白质组学和孟德尔随机化分析揭示银屑病的新蛋白质生物标志物
Rui Mao,Tongtong Zhang,Ziye Yang et al.
Rui Mao et al.
Background: Current pharmacological treatments for psoriasis are generally non-specific and have significant limitations, particularly in the realm of targeted biologic therapies. There is an urgent need to identify and d...
Zinc Supplementation for Acrodermatitis Enteropathica Overlapped with Psoriasiform Lesions [0.03%]
锌补充治疗伴有银屑病样皮损的肠病性肢端皮炎
Liangzhe Wang,Shuaijun Zou,Yuanjie Zhu
Liangzhe Wang
Acrodermatitis enteropathica (AE) can be caused by inherited or acquired zinc deficiency, among which site-specific skin lesions or even psoriasiform skin manifestations are present. Few cases exist in the literature involving the diagnosis...
The Association Between Patient-Reported Disease Burden and Treatment Switching in Patients with Plaque Psoriasis Treated with Nonbiologic Systemic Therapy [0.03%]
关于非生物系统疗法治疗银屑病患者疾病负担与转药之间的关系
Vardhaman Patel,Sang Hee Park,Yichen Zhong et al.
Vardhaman Patel et al.
Purpose: This real-world study investigated the impact of patient-reported disease burden and health-related quality of life (HRQoL) on switching from systemic nonbiologic to biologic therapy in patients with plaque psori...
Impact of IL-17A Inhibitors on Serum Uric Acid Levels in Psoriatic Patients with Hyperuricemia: A Prospective Observational Study [0.03%]
白介素-17A抑制剂对银屑病伴高尿酸血症患者血尿酸水平影响的前瞻性观察研究
Chao Wu,Chunxia He,Haimeng Wang et al.
Chao Wu et al.
Purpose: This prospective observational study investigated whether interleukin (IL)-17A inhibitors could reduce serum uric acid (SUA) levels in psoriatic patients with hyperuricemia. It also explored the risk factors for ...
Impact of GLP-1 Receptor Agonists on Psoriasis and Cardiovascular Comorbidities: A Narrative Review [0.03%]
肠泌素受体激动剂对银屑病及其心血管共病的影响:综述
Kathryn Haran,Chandler E Johnson,Payton Smith et al.
Kathryn Haran et al.
Psoriasis is an immune-mediated skin disease known to be associated with a higher risk of cardiometabolic comorbidities such as hypertension, myocardial infarction, and stroke. GLP-1 receptor agonists (GLP-1RAs) are medications approved to ...
A New Prescription Emollient Device (PED) For Psoriasis of Sensitive Areas and Folds: A Randomized Prospective Open Trial [0.03%]
新型湿疹给药装置(PED)治疗皮肤褶皱和敏感区域银屑病的随机前瞻性开放试验
Federica DallOglio,Anna Elisa Verzì,Giulia Guglielmi et al.
Federica DallOglio et al.
Purpose: Psoriasis affecting sensitive areas and folds represents a therapeutic challenging as the skin in these areas may be more prone to local pharmacological side effects. The aim of this prospective, randomized, open...
Vito Di Lernia,Cristina Bertoli
Vito Di Lernia
Psoriasis is a chronic, immunologically mediated disease of multifactorial origin, with genes playing a key role and environmental factors, such as infections, often triggering its onset or exacerbation. While acute streptococcal infections...
Metabolic Syndrome in Psoriasis and Psoriatic Arthritis in a Mixed Race Population: Comparison of Their Prevalences [0.03%]
代谢综合征在银屑病和银屑病关节炎患者中的患病率比较:一项多族裔人群研究
Patrícia Medeiros Gusmão Acioly,Mara Diane Lisboa Tavares Mazzillo,Carla Jorge Machado et al.
Patrícia Medeiros Gusmão Acioly et al.
Background: There is a growing body of evidence suggesting the association between psoriasis (PsO) and psoriatic arthritis (PsA) separately with metabolic syndrome (MS) in different populations. The literature is relative...