Assessing and Improving Psychological Well-Being in Psoriasis: Considerations for the Clinician [0.03%]
银屑病的心理健康评估及改善：临床医生的注意事项
Brittany Blackstone,Radhika Patel,Anthony Bewley
Brittany Blackstone
Psoriasis is a common chronic, systemic inflammatory disease, affecting approximately 2% of the population worldwide. Psoriasis is associated with profound psychosocial comorbidity with a burden that extends well beyond the physical signs a...
Telemedicine and e-Health in the Management of Psoriasis: Improving Patient Outcomes - A Narrative Review [0.03%]
远程医疗和电子健康在银屑病管理中的作用：改善患者预后-叙述性回顾
Alison Havelin,Philip Hampton
Alison Havelin
The role of technology in dermatology is expanding. Telemedicine and eHealth are increasingly being used by doctors and patients in the management of psoriasis. This is a narrative review of the literature relating to the use of digital tec...
Biologics in Psoriasis: Updated Perspectives on Long-Term Safety and Risk Management [0.03%]
生物制剂治疗银屑病：长期安全性和风险管理的更新观点
A Al-Janabi,Z Z N Yiu
A Al-Janabi
Biologics targeting Th1/Th17 cytokines have revolutionised psoriasis treatment. In addition to treatment effectiveness, it is important to define and understand the long-term risks of biologic therapy in order to guide therapy selection and...
The Use of Metrics in Daily Practice and the Perception of Psoriasis-Associated Comorbidities: Discrepancies Between Research and Real-World [0.03%]
指标在日常实践中的应用以及银屑病相关共病的感知：研究与现实世界之间的差异
Tom Hillary,Jo Lambert
Tom Hillary
Objective: To assess the feasibility of the future implementation of a recently published Belgian treat-to-target scoring in daily practice, we investigated to what extent Belgian dermatologists use metrics and take comor...
Non-Alcoholic Fatty Liver Disease (NAFLD) in Patients with Psoriasis: A Review of the Hepatic Effects of Systemic Therapies [0.03%]
银屑病患者的非酒精性脂肪肝疾病(NAFLD):系统性治疗的肝脏影响综述
Deepak M W Balak,Stefano Piaserico,Ismail Kasujee
Deepak M W Balak
There is increasing interest in the association between psoriasis and non-alcoholic fatty liver disease (NAFLD), which is a prevalent liver disease characterized by excessive fat storage and inflammation that can progress to fibrosis and ca...
High-Throughput RNA Sequencing Reveals the Effect of NB-UVB Phototherapy on Major Inflammatory Molecules of Lesional Psoriasis [0.03%]
高通量RNA测序揭示窄带紫外线B光疗对银屑病损伤主要炎性分子的影响
Pinyadapat Vacharanukrauh,Jitlada Meephansan,Pattarin Tangtanatakul et al.
Pinyadapat Vacharanukrauh et al.
Objective: To identify the narrowband ultraviolet B (NB-UVB)-induced molecular mechanisms that may account for their anti-inflammatory efficacy, gene expression and transcriptome profiling, which were performed using adva...
Efficacy of Brodalumab and Guselkumab in Patients with Moderate-to-Severe Plaque Psoriasis Who are Inadequate Responders to Ustekinumab: A Matching Adjusted Indirect Comparison [0.03%]
Brodalumab和Guselkumab对Ustekinumab反应不足的中重度斑块状银屑病患者的疗效：匹配调整间接比较
Philip Hampton,Emma Borg,Jes Birger Hansen et al.
Philip Hampton et al.
Purpose: Both brodalumab and guselkumab improve skin clearance in patients with moderate-to-severe plaque psoriasis after inadequate response to ustekinumab. In the absence of a direct head-to-head comparison, the relativ...
The Use of Apremilast in Psoriasis: An Indian Perspective on Real-World Scenarios [0.03%]
阿普利马斯特在银屑病治疗中的应用——印度真实世界案例的视角分析
Murlidhar Rajagopalan,Sunil Dogra,Abir Saraswat et al.
Murlidhar Rajagopalan et al.
Apremilast, an oral phosphodiesterase-4 inhibitor, is approved for use in the management of psoriasis and psoriatic arthritis. Although its efficacy and safety have been well established in clinical studies, in real-world settings, differen...
Psoriasis and Cardiometabolic Diseases: The Impact of Inflammation on Vascular Health [0.03%]
银屑病和心血管代谢性疾病：炎症对血管健康的影响
Meron Teklu,Philip M Parel,Nehal N Mehta
Meron Teklu
Psoriasis is a common chronic inflammatory condition associated with a higher risk of cardiovascular disease. Psoriasis confers a dose-dependent increase in risk for the metabolic syndrome and its components. The metabolic syndrome and its ...
Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics [0.03%]
银屑病的关键信号通路：抗银屑病药物带来的最新启示
Hakim Ben Abdallah,Claus Johansen,Lars Iversen
Hakim Ben Abdallah
Psoriasis is a common chronic inflammatory skin disease associated with several comorbidities and reduced quality of life. In the past decades, highly effective targeted therapies have led to breakthroughs in the management of psoriasis, pr...