Cell Therapy Using Anti-NKG2A Pretreated Natural Killer Cells in Patients with Hepatocellular Carcinoma [0.03%]
抗NKG2A自然杀伤细胞体外预处理细胞治疗肝癌患者安全性和有效性的临床研究
Shirin Tavakoli,Maryam Samareh-Salavati,Shahrokh Abdolahi et al.
Shirin Tavakoli et al.
Purpose: The activities and functions of natural killer (NK) cells are regulated by a limited repertoire of activating and inhibitory receptors. Thus, we provided a study of inhibition of the NKG2A using monoclonal antibo...
Targeted Therapy Evolution from Defining a Sub-population to Crossing Multi-indications [0.03%]
精准治疗从定义亚群到跨适应症的发展历程
Daohong Chen
Daohong Chen
Purpose: It tends not only to shed lights on an emerging classification framework of disease according to the shared molecular pathogenesis across various organs/tissues, but also to inspire more efficient paradigms of ph...
Preparation, Characterization, and Leishmanicidal Assessment of Silver- and Dapsone-Loaded Niosomes Co-administration: In Silico and In Vitro Study [0.03%]
基于尼奥斯omes载体的含银和二丙酸丁二醇酯联合用药的制备、表征及体内体外抗利什曼病活性评估及分子模拟研究
Anna Etemadifar,Sina Bahraminejad,Abbas Pardakhty et al.
Anna Etemadifar et al.
Purpose: Currently, there is a crucial need for alternative strategies to control leishmaniasis, which threatens more than 1 billion people worldwide. The simultaneous use of combination therapy and nanostructured lipid c...
Rethinking the Complexation of Phytochemicals in Natural β-Cyclodextrins [0.03%]
天然β-环糊精中植物化学成分复合物的再思考
Ian Jhemes Oliveira Sousa,Rita de Cássia Meneses Oliveira
Ian Jhemes Oliveira Sousa
The Effect of Statin Therapy on Bone Metabolism Markers and Mineral Density: Aa GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials [0.03%]
他汀类药物治疗对骨代谢标志物和矿物质密度的影响：基于GRADE的系统评价和随机对照试验的剂量反应meta分析
Seyyed Mostafa Arabi,Mahla Chambari,Leila Sadat Bahrami et al.
Seyyed Mostafa Arabi et al.
Purpose: Statin therapy is widely used for the management of dyslipidemia and the prevention of cardiovascular diseases (CVDs). However, there is a growing concern about its potential effects on bone metabolism markers an...
Harnessing the Therapeutic Potential of Mesenchymal Stem Cells in Cancer Treatment [0.03%]
利用间充质干细胞在癌症治疗中的潜在疗效
Parisa Kangari,Reza Salahlou,Somayeh Vandghanooni
Parisa Kangari
Cancer, as a complicated disease, is considered to be one of the major leading causes of death globally. Although various cancer therapeutic strategies have been established, however, some issues confine the efficacies of the treatments. In...
NLC Delivery of EGFP Plasmid to TM4 Cell Nuclei for Targeted Gene Therapy [0.03%]
用于靶向基因治疗的TM4细胞核内递送EGFP质粒
Nurul Jummah,Satrialdi Satrialdi,Aluicia Anita Artarini et al.
Nurul Jummah et al.
Purpose: This study evaluated whether a nanostructured lipid carrier (NLC) delivery system could safely and accurately deliver nucleic acids to the cell nucleus using the enhanced green fluorescent protein (EGFP)-C1 plasm...
Development of Gentamicin Bilosomes Laden In Situ Gel for Topical Ocular Delivery: Optimization, In Vitro Characterization, Toxicity, and Anti-microbial Evaluation [0.03%]
万古霉素倍半脂质体载药凝胶的优化、体外表征、毒性及抗菌评价
Ameeduzzafar Zafar,Omar Awad Alsaidan,Malik Suliman Mohamed et al.
Ameeduzzafar Zafar et al.
Purpose: The eye drops are the prominent preparation used to treat surface eye disease (bacterial conjunctivitis). However, they have some limitations i.e., short corneal residence, resulting in low ocular bioavailability...
Navigating Scientific Peer Review with ChatGPT: Ally or Adversary? [0.03%]
ChatGPT在科学同行评审中的角色：盟友还是对手？
ArunSundar MohanaSundaram
ArunSundar MohanaSundaram
Co-targeting of HMG-Co-A Reductase and Cycloxygenase-2 for the Treatment of Non-small Cell Lung Cancer [0.03%]
HMG-Co-A还原酶和环氧化酶-2共作用靶点治疗非小细胞肺癌研究
Ashutosh Sharma,Ammu V V V Ravi Kiran,Praveen T Krishnamurthy
Ashutosh Sharma