Mihály Hegedűs,Mehdi Dadkhah,Lóránt Dénes Dávid
Mihály Hegedűs
Purpose: Hijacked journals are fraudulent websites that mimic legitimate journals and, by charging authors, publish manuscripts. The current editorial endeavors to provide a close view of current literature. This editoria...
Navigating the Impact of India's Recent Ban on Fixed-Dose Combinations: A Call for Evidence-Based Regulation [0.03%]
印度禁止固定剂量复合制剂的影响及基于证据的监管呼吁
Muhammed Favas Kt,Guru Datt Sharma,Sanjit Sah
Muhammed Favas Kt
Maternal Metformin Administration During the Pre-Gestation Period Improves Transient Cerebral Ischemia Injury in Male Offspring Rats [0.03%]
孕前母体使用二甲双胍改善雄性子代大鼠短暂脑缺血损伤
Reyhaneh Vaali,Iraj Ahmadi,Fradin Sehati et al.
Reyhaneh Vaali et al.
Purpose: It seems that maternal intervention, which may involve epigenetic mechanisms, can affect cerebral ischemia in offspring. Metformin consumption by the mother activates the AMP-activated protein kinase (AMPK) pathw...
Green Formulation of Menadione-Loaded Niosome as a Skin-Lightening Preparation: In Vitro / In Vivo Safety Evaluation on Wistar Rat [0.03%]
绿色合成载维生素K3尼奥斯omes护肤品的体内外安全性评价研究
Majid Saeedi,Katayoun Morteza-Semnani,Jafar Akbari et al.
Majid Saeedi et al.
Purpose: In the present research, a green technique (an ultrasonic method) was used to synthesize menadione sodium bisulfite (MSB) niosome (Menasome) which is used to improve dermal delivery and increase anti-melanogenesi...
Metabolomic Approach in Anticancer Biomarker Discovery from Foliose Lichens [0.03%]
用于抗癌生物标志物发现的叶状地衣代谢组学研究方法
Chintya Permata Zahky Sukrisno Putri,Dinar Mutia Rani,Ludmilla Fitri Untari et al.
Chintya Permata Zahky Sukrisno Putri et al.
Purpose: Lichens are well-known as a source of pharmacologically active compounds. This includes anticancer compounds which have biomass constraints including using traditional techniques of lichen bioprospecting. This cu...
Peyvand Bahramiazar,Naseh Abdollahzade,Bakhtyar Tartibian et al.
Peyvand Bahramiazar et al.
Purpose: This review aims to elucidate the role of estrogen-sensitive microRNAs (miRNAs) in modulating brain functions and disorders, highlighting the protective effects of estrogen on the central nervous system. ...
Developing and Applying a Single Strategy for Improved Intestinal Permeability of Diverse and Complex Phytomolecules: Nanoformulations of Rutin, Quercetin, Thymoquinone Provide Proof-of-Concept [0.03%]
用于改善植物分子肠道通透性的单一策略的开发与应用：芦丁、山柰酚和百里醌的纳米递送系统提供概念验证
Rajani Mathur,Sahiba Khan,Ruchi Tripathi et al.
Rajani Mathur et al.
Purpose: The clinical use and efficacy of phytomolecules are often hampered as their complex structure, poor aqueous solubility and low biological stability restricts their intestinal permeability which results in low ora...
Challenges of Serum Creatinine Level in GFR Assessment and Drug Dosing Decisions in Kidney Injury [0.03%]
肾损伤时评估肾小球滤过率和药物剂量调整中的血清肌酐水平面临的挑战
Xinyi Wang,Jing Mu,Kexin Ma et al.
Xinyi Wang et al.
Serum creatinine (SCr) is widely regarded as a standard biomarker for assessing glomerular filtration rate (GFR) and is commonly used to guide dose adjustments for renally eliminated drugs. However, the application of SCr as a marker for ev...
Niosome as a Drug Delivery Carrier for Sorafenib: Preparation, Investigation of Physicochemical Properties, and In Vitro Effects on HepG2 Cell Line [0.03%]
纳米囊泡载 Sorafenib 制备及物理化学性质研究和体外 HepG2 细胞实验效果探讨
Mohammad Amin Raeisi Estabragh,Behzad Behnam,Masoud Torkzadeh-Mahani et al.
Mohammad Amin Raeisi Estabragh et al.
Purpose: Sorafenib is known as one of the oral anti-cancer drugs used in liver cancer. However, its lipophilic nature can lead to side effects, variable pharmacokinetics, and poor absorption. The use of novel drug deliver...
Combining Chemotherapy Agents and Autophagy Modulators for Enhanced Breast Cancer Cell Death [0.03%]
联合使用化疗药物和自噬调控剂增强乳腺癌细胞的死亡
Soraya Moomivand,Mohsen Nikbakht,Ahmad Majd et al.
Soraya Moomivand et al.
Purpose: Autophagy, governed by genes with dual roles in cell death and survival, plays a crucial role in cancer persistence. Arsenic trioxide (ATO), carboplatin (CP), and cyclophosphamide (CY) are used to treat various c...