Genosomes: An Introspection into Transfection, Future Perspectives and Applications [0.03%]
基因体：转染的自我审视、未来展望及应用
Abhirami Subramony,Divyatha Raj,Fiza Fairooz et al.
Abhirami Subramony et al.
The advent of advanced gene delivery platforms has transformed the precision targeting of therapeutic nucleic acids, such as miRNA, siRNA, and pDNA, for the treatment of genetic and acquired diseases, including cystic fibrosis, malignancies...
Evaluating the Efficacy of a Semi-Solid Formulation with Clove Oil and Curcumin versus Clindamycin in the Treatment of Acne Vulgaris: A Comprehensive Study of Preclinical and Clinical Findings [0.03%]
含姜黄素和丁香油半固体制剂与克林霉素治疗寻常痤疮的疗效评估：前期及临床研究综合分析
Peymaneh Dastgir,Setareh Tehrani,Setareh Haghighat et al.
Peymaneh Dastgir et al.
Purpose: Acne vulgaris is a chronic inflammatory condition affecting the pilosebaceous units. With the rise of antibiotic resistance and the potential side effects associated with conventional treatments, there is increas...
Continuous Uptake of MiR-181a-2 Mimetic Induces Constitutive Overexpression of Cellular MiR-181a-2 in MCF-7 Breast Cancer Cells: Links with Progression of Drug Resistance [0.03%]
微RNA-181a-2模拟物的持续摄入可在MCF-7乳腺癌细胞中诱导细胞微小核糖核酸-181a-2过度表达：与耐药性进展的关系
Olga Evgen&#x;evna Andreeva,Danila Vladimirovich Sorokin,Svetlana Vladimirovna Vinokurova et al.
Olga Evgen&#x;evna Andreeva et al.
Purpose: The aim of this study was to elucidate the mechanisms underlying the formation and maintenance of drug resistance in cancer cells. Previously, we demonstrated that prolonged treatment of estrogen-dependent MCF-7 ...
An Insight Into the Aerosolization Pattern of Formoterol Fumarate Dry Powder Inhalation Formulation Actuated Via Two Different Inhaler Devices [0.03%]
一种福莫特罗富马酸 dry powder吸入制剂通过两种不同吸入器给药的气溶胶化模式分析
Leila Asadollahi,Reza Ghanbari,Soheil Abbaspour-Ravasjani et al.
Leila Asadollahi et al.
Purpose: Effective inhaled drug delivery is essential for managing bronchial asthma and chronic obstructive pulmonary disease (COPD). This study compared the aerosolization efficiency of two different dry powder inhalers ...
Pathological and Molecular Significance of HER2/neu Overexpression in Familial Breast Cancer Among Egyptian Women: A Comprehensive Study on Diagnostic and Prognostic Implications [0.03%]
埃及女性家族性乳腺癌HER2/neu过度表达的病理及分子意义：关于诊断和预后意义的全面研究
Amoura M Abou-El-Naga,Afaf M El Saied,Maher Monir Akl et al.
Amoura M Abou-El-Naga et al.
Purpose: Breast cancer remains the most prevalent malignancy among women worldwide, with a strikingly high incidence in Egypt, particularly in familial cases. This study aims to comprehensively elucidate the pathological ...
siRNA and mRNA-Based Preventive and Therapeutic Strategies for HPV-Induced Cervical Cancer [0.03%]
针对HPV诱发宫颈癌的siRNA和mRNA防治策略研究进展
Mansi Khari,Neha Jain,Shreya Kaul et al.
Mansi Khari et al.
Human papillomavirus (HPV), specifically types 16 and 18, is the main cause of cervical cancer and a significant cause of death among women. Specifically, HPV E6 and E7 oncogenes hinder the normal cell cycle regulation, resulting in uncontr...
The Pharmaceutical Industry's Future: How Artificial Intelligence is Transforming Medicine [0.03%]
药物行业的未来：人工智能如何改变医学
Barnika Debnath,Samson K Wilson,Subhrajyoty Basu et al.
Barnika Debnath et al.
In the pharmaceutical industry, artificial intelligence (AI) is revolutionizing individualized therapy, research, and drug development. AI includes machine learning (ML) and deep learning (DL), that are used to read enormous amounts of data...
Novel approach in HIV therapy: lipid nanoparticle-based mRNA delivery technology using LNP X-HIV Tat-CRISPRa system [0.03%]
新型HIV治疗策略：基于脂质纳米颗粒的mRNA递送技术及LNP X-HIV Tat-CRISPRa系统
Aminath Efa Ibrahim,Kannan Subbaram,Razana Faiz et al.
Aminath Efa Ibrahim et al.
Toll-Like Receptor-4 Signaling Pathway Influenced the Exosome Biogenesis and Angiogenesis in Human Triple-Negative Breast Cancer Cells [0.03%]
toll样受体4信号通路影响人类三阴性乳腺癌细胞的外泌体发生及血管生成
Parisa Khanicheragh,Çığır Biray Avci,Zahra Abbasi-Malati et al.
Parisa Khanicheragh et al.
Purpose: The close relationship of the toll-like receptor (TLR) signaling pathway has been indicated with different bioactivates of tumor cells. Here, the impact of TLR4 signaling pathway stimulation/inhibition was assess...
Exploring Cuscuta epithymum's Effect on Neuroinflammation, Tyrosine Kinase Activity and Macrophage Counts in Spleen and Liver: Revealing Their Roles in Stress Responses [0.03%]
靶向神经炎症、酪氨酸激酶活性及应激反应中脾脏和肝脏巨噬细胞数量的策略：基于槲寄生根茎的研究
Leila Ghassemifard,Narjes Khavasi,Ehsan Saboory et al.
Leila Ghassemifard et al.
Purpose: Chronic stress usually causes immunosuppression, activates tyrosine kinase (TK), and increases inflammatory responses. Based on Persian medicine, the spleen is crucial for the immune system and stress response. C...