Robert S Parker,Justin S Hogg,Anirban Roy et al.
Robert S Parker et al.
The body responds to endotoxins by triggering the acute inflammatory response system to eliminate the threat posed by gram-negative bacteria (endotoxin) and restore health. However, an uncontrolled inflammatory response can lead to tissue d...
A Visualization and Control Strategy for Dynamic Minimization of Chemical Process Releases [0.03%]
用于动态最小化化工流程释放物的可视化与控制策略
Shuyun Li,Gerardo J Ruiz-Mercado,Fernando V Lima
Shuyun Li
Our societal needs for greener, economically viable products and processes have grown given the adverse environmental impact and unsustainable development caused by human activities, including chemical releases, exposure, and impacts. To ma...
Increasing Salt Rejection of Polybenzimidazole Nanofiltration Membranes via the Addition of Immobilized and Aligned Aquaporins [0.03%]
通过添加固定并定向的水通道蛋白来提高聚苯并咪唑纳米过滤膜的盐截留率
Priyesh Wagh,Xinyi Zhang,Ryan Blood et al.
Priyesh Wagh et al.
Aquaporins are water channel proteins in cell membrane, highly specific for water molecules while restricting the passage of contaminants and small molecules, such as urea and boric acid. Cysteine functional groups were installed on aquapor...
Babita K Verma,Pushpavanam Subramaniam,Rajanikanth Vadigepalli
Babita K Verma
Liver resection is an important clinical intervention to treat liver disease. Following liver resection, patients exhibit a wide range of outcomes including normal recovery, suppressed recovery, or liver failure, depending on the regenerati...
Algorithms for a Single Hormone Closed-Loop Artificial Pancreas: Challenges Pertinent to Chemical Process Operations and Control [0.03%]
单激素人工胰腺闭环算法的挑战：与化学过程操作和控制有关的问题
B Wayne Bequette,Faye Cameron,Nihat Baysal et al.
B Wayne Bequette et al.
The development of a closed-loop artificial pancreas to regulate the blood glucose concentration of individuals with type 1 diabetes has been a focused area of research for over 50 years, with rapid progress during the past decade. The dail...
Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment [0.03%]
肿瘤免疫微环境的多尺度代理和混合建模方法研究进展
Kerri-Ann Norton,Chang Gong,Samira Jamalian et al.
Kerri-Ann Norton et al.
Multiscale systems biology and systems pharmacology are powerful methodologies that are playing increasingly important roles in understanding the fundamental mechanisms of biological phenomena and in clinical applications. In this review, w...
Towards an Aspect-Oriented Design and Modelling Framework for Synthetic Biology [0.03%]
一种面向方面的合成生物学设计与模型框架的研究
Philipp Boeing,Miriam Leon,Darren N Nesbeth et al.
Philipp Boeing et al.
Work on synthetic biology has largely used a component-based metaphor for system construction. While this paradigm has been successful for the construction of numerous systems, the incorporation of contextual design issues-either compositio...
On the Use of Multivariate Methods for Analysis of Data from Biological Networks [0.03%]
多元方法用于生物网络数据的分析
Troy Vargason,Daniel P Howsmon,Deborah L McGuinness et al.
Troy Vargason et al.
Data analysis used for biomedical research, particularly analysis involving metabolic or signaling pathways, is often based upon univariate statistical analysis. One common approach is to compute means and standard deviations individually f...
ADAR Mediated RNA Editing Modulates MicroRNA Targeting in Human Breast Cancer [0.03%]
ADAR介导的RNA编辑调节人类乳腺癌中的MicroRNA靶标作用
Justin T Roberts,Dillon G Patterson,Valeria M King et al.
Justin T Roberts et al.
RNA editing by RNA specific adenosine deaminase acting on RNA (ADAR) is increasingly being found to alter microRNA (miRNA) regulation. Editing of miRNA transcripts can affect their processing, as well as which messenger RNAs (mRNAs) they ta...
A Computational Study of the Effects of Syk Activity on B Cell Receptor Signaling Dynamics [0.03%]
基于Syk活性对B细胞受体信号转导动力学的计算研究
Reginald L McGee,Mariya O Krisenko,Robert L Geahlen et al.
Reginald L McGee et al.
The kinase Syk is intricately involved in early signaling events in B cells and is required for proper response when antigens bind to B cell receptors (BCRs). Experiments using an analog-sensitive version of Syk (Syk-AQL) have better elucid...