Medication Adherence and Risks of Mortality and End-Organ Damage in Asian Patients with Type 2 Diabetes: A Cohort Study from Southern Taiwan [0.03%]
亚洲2型糖尿病患者药物依从性与死亡及靶器官损害风险的关系——台湾南部地区人群队列研究
Peng-Wen Chen,Ming-Chieh Lin,Tzu-Jung Fang et al.
Peng-Wen Chen et al.
Background: Medication adherence is a critical component of effective management in type 2 diabetes mellitus (T2DM). Although previous studies have explored the relationship between adherence and clinical outcomes, the strength and consiste...
Pan-Cancer Analysis Identifies SNORA12 as a Prognostic Biomarker and Demonstrates Its Role in Upregulating TIGIT in Osteosarcoma [0.03%]
泛癌分析鉴定SNORA12作为预后生物标志物并证明其在上调骨肉瘤TIGIT中的作用
Weiwei He,Wenbo Shi,Qian Li et al.
Weiwei He et al.
Background: Small nucleolar RNAs (snoRNAs) are emerging regulators of tumorigenesis, yet their pan-cancer landscape and immunological roles remain poorly defined. This study investigates the expression pattern, prognostic significance, and ...
Electrospun PVA Nanofibers Co-Loaded with Atorvastatin and Zinc Oxide for Antibacterial and In Vitro Wound Healing Applications [0.03%]
载阿托伐他汀和氧化锌的聚乙烯醇纳米纤维及其抗菌和体外伤口愈合研究
Rawan Fitaihi,Alanoud Altalal,Rihaf Alfaraj et al.
Rawan Fitaihi et al.
Background: The global rise in antimicrobial resistance (AMR) has created an urgent need for innovative antibacterial strategies and localized delivery systems. This study aimed to develop and characterize electrospun poly (vinyl alcohol) (...
A Pilot Study Investigating Clinical and Functional Outcomes of Novel Double-Coil rPMS in Knee Osteoarthritis [0.03%]
新型双线圈rPMS治疗膝关节骨性关节炎的临床和功能结局的研究试点研究
Roman Bednár,Martina Flašková,Nicole Fejková
Roman Bednár
Background: Knee osteoarthritis (KOA) is one of the leading causes of chronic pain and long-term disability worldwide. Despite its high prevalence, KOA remains underrepresented in repetitive peripheral magnetic stimulation (rPMS) research. ...
László Barkai
László Barkai
Background/Objectives: The global incidence of diabetes in childhood is increasing, raising concern about its long-term effects on the developing brain. Although paediatric diabetes research has traditionally focused on microvascular and ma...
Combined Antineoplastic Effects of Metformin, Boric Acid and Resveratrol in SKOV3 Ovarian Cancer Cells [0.03%]
二甲双胍、硼酸和白藜芦醇联合抗肿瘤作用的SKOV3细胞系卵巢癌研究
Burcu Biltekin,Mete Hakan Karalok,Seyma Dumur et al.
Burcu Biltekin et al.
Background: Ovarian cancer (OC) is characterized by aggressive progression, high metastatic potential, and frequent resistance to conventional chemotherapy, highlighting the need for novel combination-based therapeutic strategies. Metformin...
Serum Protein Electrophoresis and the Albumin-to-Globulin Ratio in the Differential Diagnosis of Minimal Change Disease and Focal Segmental Glomerulosclerosis [0.03%]
血清蛋白电泳和白蛋白/球蛋白比值在微小病变与局灶性节段性肾小球硬化鉴别诊断中的价值研究
László Bitó,Tamás Lantos,Krisztina Jost et al.
László Bitó et al.
Background/Objectives: Differentiating minimal change disease (MCD) from focal segmental glomerulosclerosis (FSGS) remains a diagnostic challenge. We hypothesised that differences in glomerular protein selectivity could translate into disti...
Rheopheresis, but Not Phlebotomy, Improves Cerebral Vascular Response to Hypercapnia and Neuronal Activation [0.03%]
血浆置换，而不是放血，改善了高碳酸血症下的脑血管反应和神经元激活状况
Dóra Sulina,Szonja Krisztina Rab-Bábel,Ádám Varga et al.
Dóra Sulina et al.
Background/Objectives: Several therapeutic approaches, including phlebotomy and rheopheresis, are used to improve hemorheological parameters. While the effects of phlebotomy on cerebral circulation have been described, the impact of rheophe...
Anthracycline-Free Neoadjuvant Pertuzumab-Trastuzumab-Taxane in Patients with HER2-Positive Early Breast Cancer: Hormone Receptor Status as a Key Determinant of Pathological Complete Response [0.03%]
无蒽环类新辅助帕妥珠单抗曲妥珠单抗紫杉醇治疗HER2阳性早期乳腺癌患者：激素受体状态是病理完全缓解的关键决定因素
Azzurra Irelli,Tina Sidoni,Francesco Pavese et al.
Azzurra Irelli et al.
Background: Neoadjuvant chemotherapy plus dual HER2 blockade is standard for HER2-positive early breast cancer (EBC), but the impact of hormone receptor (HR) status and PIK3CA mutations with anthracycline-free regimens remains unclear. Meth...
Predicting 1-Year Trifecta Outcomes After High-Intensity Focused Ultrasound and Cryoablation for Low- and Intermediate-Risk Prostate Cancer [0.03%]
低风险和中等风险前列腺癌高强度聚焦超声及冷冻消融术后一年预后的预测指标
Umberto Anceschi,Antonio Tufano,Gabriele Tuderti et al.
Umberto Anceschi et al.
Objectives: Focal therapy (FT) is increasingly employed in selected patients with localized prostate cancer (PCa), aiming to balance oncologic control with preservation of urinary and sexual function. Among the available energy sources, pro...