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Meritxell Pérez,Juan José Lozano,Mercedes Ingelmo-Torres et al.
Meritxell Pérez et al.
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Biomedicines. 2026 Jul 17;14(7):1604. DOI:10.3390/biomedicines14071604 2026
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Yuya Izubuchi et al.
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Biomedicines. 2026 Jul 7;14(7):1520. DOI:10.3390/biomedicines14071520 2026
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Elena Kolodkina
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Mandibular Advancement Device Therapy in 182 DISE-Selected Adults with Moderate-to-Severe Obstructive Sleep Apnea: A Multicenter Real-World Study [0.03%]
成人中重度阻塞性睡眠呼吸暂停综合征MANDIBULAR ADVANCEMENT DEVICE治疗的多中心真实世界研究(DISE选择患者,n=182)
Marc J Braem,Muriel Lins,Annelies Van Den Bergh et al.
Marc J Braem et al.
Background/Objectives: The study evaluates the effectiveness of mandibular advancement device (MAD) treatment in drug-induced sleep endoscopy (DISE) preselected adults with moderate-to-severe obstructive sleep apnea (OSA). Methods: It is a ...
Discovery of a Novel 4,5-Dihydro-1 H-pyrazole-1-carbothioamide Derivative with Cytotoxic, Apoptotic, and ABL1 Inhibitory Activities Against Chronic Myeloid Leukemia [0.03%]
一种针对慢性髓性白血病具有细胞毒、促凋亡和ABL1抑制作用的新型4,5-二氢-1H-吡唑-1-甲硫酰胺衍生物的发现
Ayben Erkan,Ayca Irgit Calayir,Halilibrahim Ciftci et al.
Ayben Erkan et al.
Background/Objectives: Chronic myeloid leukemia (CML) is a hematological malignancy driven by the constitutively active BCR-ABL1 fusion protein. Although current ABL1 tyrosine kinase inhibitors (TKIs) have improved CML management, resistanc...
Occult Parathyroid Lesions on 99mTc-Sestamibi Scintigraphy: Morphometric, Histopathological and Anatomical Determinants of Detection [0.03%]
99mTc-MIBI显像隐匿性甲状旁腺病变的检出与形态计量、病理及解剖特征的关系
Oriana-Eliana Pelineagră,Ioana Golu,Melania Balaș et al.
Oriana-Eliana Pelineagră et al.
Background: Accurate preoperative localization of hyperfunctioning parathyroid glands remains challenging, particularly in secondary hyperparathyroidism where multiglandular disease may compromise scintigraphic performance. Methods: Our stu...
Reannotation of Public Transcriptomic Data Identifies Candidate lncRNAs and Putative Regulatory Networks in Rhabdomyosarcoma [0.03%]
对公共转录组数据的重新注释识别出横纹肌肉瘤中的候选lncRNA和推定调节网络
Jessica Zablocki da Luz,Leonardo Vinícius Barbosa,Thiago Rodrigues Dos Santos et al.
Jessica Zablocki da Luz et al.
Background/Objectives: Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma, includes two main subtypes, embryonal (eRMS) and alveolar (aRMS), each with distinct molecular and clinical characteristics. Although cellular pro...
Sickle Cell Disease: From Ancient Origins to Modern Breakthroughs in Gene Therapy [0.03%]
镰状细胞病:从古代起源到现代基因治疗的突破
Bawo Ikolo,Mathew Oyelami,Odinaka Mgbeke et al.
Bawo Ikolo et al.
Sickle Cell Disease (SCD) is a hereditary hemoglobinopathy arising from a single-nucleotide transversion (GAG → GTG) at codon six of the HBB gene on chromosome 11, substituting glutamic acid with valine in the β-globin chain and producing...
Apabetalone Drives a Metabolic Shift Towards Ketogenesis and Reduces Liver Steatosis in Diet-Induced Obesity Mice [0.03%]
Apabetalone诱导向酮体生成的代谢转换并减少饮食诱导的肥胖小鼠的肝脂肪变性
Laura M Tsujikawa,Agostina Carestia,Sylwia Wasiak et al.
Laura M Tsujikawa et al.
Background/Objectives: Obesity can cause metabolic disorders and hepatic steatosis. Continuous hepatic influx of dietary lipids leads to adaptive metabolic changes, including increased fatty acid oxidation (FAO) and ketogenesis. However, th...
Losartan Ameliorates Coronary Neointimal Thickening in a Mouse Model of Kawasaki Disease: A Pilot Study [0.03%]
洛沙坦改善川崎病小鼠模型冠状动脉新生内膜增厚:一项初步研究
Eisuke Suganuma,Satoko Honda,Rina Umiguchi et al.
Eisuke Suganuma et al.
Background: Patients with Kawasaki disease (KD) who develop coronary artery aneurysms (CAAs) are at increased risk of future fatal coronary events. Pharmacotherapeutic strategies to prevent coronary stenosis are still lacking. In this explo...