Integrating Technology into Urticaria Management: Telemedicine, Remote Monitoring and Patient-Centered Care [0.03%]
痒症管理中的技术整合：远程医疗、监测和以患者为中心的治疗护理
Ester Topa,Mattia Cristallo,Angela Rizzi et al.
Ester Topa et al.
Background: Urticaria, particularly chronic urticaria (CU), is a highly prevalent inflammatory skin disorder characterized by recurrent wheals and/or angioedema with a fluctuating and unpredictable course that significantly impairs quality ...
Open Pilonidal Excision as a Translational Human Model for Wound Healing and Skin Regeneration Research [0.03%]
开放式枕骨切开术作为伤口愈合和皮肤再生研究的转化人类模型
Dimitrios Vardakostas,Zoe Garoufalia,Anastassios Philippou et al.
Dimitrios Vardakostas et al.
Background/Objectives: Wound healing is a complex biological process involving coordinated interactions among inflammatory cells, growth factors, extracellular matrix components, and resident tissue cells. Despite significant advances in ex...
Combined Circulating microRNA and Inflammatory Cytokine Profiles Improve Disease-Stage Discrimination of Charcot Foot in Egyptian Patients with Type 2 Diabetes Mellitus [0.03%]
结合循环miRNA和炎症细胞因子谱型可改善埃及2型糖尿病患者Charcot足病分期的鉴别能力
Heba Ibrahim Hamed,Ihab Nabil Amin,Salwa Bakr Hassan et al.
Heba Ibrahim Hamed et al.
Background/Objectives: Diabetic peripheral neuropathy (DPN) and Charcot foot (CF) represent progressive and disabling neuropathic complications of type 2 diabetes mellitus (T2DM). Circulating microRNAs and inflammatory cytokines may reflect...
MRI-Based Synovial Iron Quantification Associates with Bone Erosion in Rheumatoid Arthritis [0.03%]
基于磁共振的滑膜铁沉积量化与类风湿性关节炎骨侵蚀的关系
Shuyuan Zhong,Churong Lin,Jianhua Ren et al.
Shuyuan Zhong et al.
Objective: To evaluate the utility of synovial iron quantification using Magnetic resonance imaging (MRI) in assessing structural joint damage in the knee of patients with rheumatoid arthritis (RA). Methods: This cross-sectional study emplo...
Prognostic Role of High-Sensitivity C-Reactive Protein/Albumin Ratio in Heart Failure Patients [0.03%]
高敏C反应蛋白/白蛋白比率在心力衰竭患者中的预后价值
Domenico Martire,Giuseppe Armentaro,Giandomenico Severini et al.
Domenico Martire et al.
The ratio of high-sensitivity C-reactive protein (hs-CRP) to Serum albumin (SA) (hs-CRP/SA) is emerging as a new potential biomarker capable of stratifying cardiovascular risk in patients with chronic HF (CHF), particularly the risk of majo...
Baseline Composite Score for 12-Month Clinical Remission in Biologic-Treated Severe Asthma: Development of the Base4Score [0.03%]
生物制剂治疗的重度哮喘患者一年临床缓解基线综合评分模型的研发(Base4Score)
Juan Luis García-Rivero,Adil Hannaoui Anaaoui,Abel Pallarés-Sanmartín et al.
Juan Luis García-Rivero et al.
Background: Clinical remission has become a realistic treatment goal in severe asthma, but current evidence mostly reports global remission rates without accounting for baseline disease burden. No simple tool exists to quantify baseline sev...
Transcriptional Heterogeneity of Cardiac Remodeling Between Type 1 and Type 2 Diabetes [0.03%]
1型糖尿病和2型糖尿病的心脏重塑转录异质性研究
Feng Liang,Shaohua Li,Guo Zhou et al.
Feng Liang et al.
Background: Cardiovascular complications stemming from diabetes pose a grave threat to patients' survival. Both type 1 diabetes (T1D) and type 2 diabetes (T2D) significantly increase the risk of heart failure, yet no reports have clarified ...
Proteomic and Metabolomic Analyses of HPV-Positive High-Grade Squamous Intraepithelial Lesions [0.03%]
HPV阳性高级别鳞状上皮内病变的蛋白质组和代谢组分析
Chengcheng Zhao,Yan Li,Yingfei Lu et al.
Chengcheng Zhao et al.
Background/Objectives: Long-term exposure to high-risk human papilloma virus (HPV) leads to high-grade squamous intraepithelial lesions (HSILs), which may develop into cancer. Various proteins and metabolites change during the development o...
Progranulin Is a Useful Biomarker to Predict Mortality in ICU Patients with Low Burden of Organ Dysfunction [0.03%]
蛋白酶素可作为预测低器官功能障碍负担的重症监护病房患者死亡率的生物标志物
Jochen Johannes Schoettler,Lutz Pridzun,Bertram Flehmig et al.
Jochen Johannes Schoettler et al.
Background/Objectives: Early prognostication in critically ill patients with low burden of organ dysfunction (BOD) remains challenging. Progranulin (PGRN), a hypoxia inducible and anti-inflammatory protein, may offer prognostic value. We in...
Integrating GLP-1 Receptor Agonists into Modern Stroke Prevention: Evidence, Mechanisms, and Clinical Consideration-A Narrative Review [0.03%]
肠促胰素受体激动剂在现代卒中预防中的应用：证据、机制及临床考量——叙事综述
Shayan Khan,William Herbst,Farbod Zahedi Tajrishi et al.
Shayan Khan et al.
Stroke remains a major cause of morbidity and mortality worldwide. Although reperfusion therapies and secondary prevention have advanced, the global stroke burden continues to rise, driven by increasing rates of hypertension and diabetes me...