TCEPVDB: Artificial Intelligence-Based Proteome-Wide Screening of Antigens and Linear T-Cell Epitopes in the Poxviruses and the Development of a Repository [0.03%]
基于人工智能的痘病毒抗原和线性T细胞表位泛蛋白质组筛选及数据库构建
Mansi Dutt,Anuj Kumar,Ali Toloue Ostadgavahi et al.
Mansi Dutt et al.
Background: Poxviruses constitute a family of large dsDNA viruses that can infect a plethora of species including humans. Historically, poxviruses have caused a health burden in multiple outbreaks. The large genome of pox...
Integrated Analysis of Proteomic Marker Databases and Studies Associated with Aging Processes and Age-Dependent Conditions: Optimization Proposals for Biomedical Research [0.03%]
蛋白质组标志物数据库及与衰老过程和年龄依赖性疾病相关研究的综合分析：生物医学研究的优化建议
Mikhail S Arbatskiy,Dmitriy E Balandin,Alexey V Churov
Mikhail S Arbatskiy
Background: The search for reliable aging biomarkers using proteomic databases and large-scale proteomic studies presents a significant challenge in biogerontology. Existing proteomic databases and studies contain valuable information; howe...
Mimicry in the Bite: Shared Sequences Between Aedes aegypti Salivary Proteins and Human Proteins [0.03%]
蚊子的唾液蛋白与人的蛋白质序列有相同之处
Andrea Arévalo-Cortés,Daniel Rodriguez-Pinto
Andrea Arévalo-Cortés
Background: Molecular mimicry contributes to the development of unwanted responses to self-antigens. Autoimmune phenomena have been observed in diseases caused by Aedes aegypti-transmitted arboviruses, but the occurrence ...
Identification of Protein Markers for Chronic Ischemic Heart Disease Through Integrated Analysis of the Human Plasma Proteome and Genome-Wide Association Data [0.03%]
通过整合人类血浆蛋白质组和全基因组关联数据识别慢性缺血性心脏病的蛋白质标志物
Chunyang Ren,Gan Qiao,Jianping Wu et al.
Chunyang Ren et al.
Background: Chronic ischemic heart disease (CIHD) is characterized by persistent myocardial ischemic due to long-term reduced coronary blood flow. In the past, we mainly relied on surgical intervention or drug therapy to ...
Recent Advances and Application of Machine Learning for Protein-Protein Interaction Prediction in Rice: Challenges and Future Perspectives [0.03%]
机器学习在水稻蛋白质-蛋白质相互作用预测中的最新进展及应用：挑战与未来展望
Sarah Bernard Merumba,Habiba Omar Ahmed,Dong Fu et al.
Sarah Bernard Merumba et al.
Protein-protein interactions (PPIs) are significant in understanding the complex molecular processes of plant growth, disease resistance, and stress responses. Machine learning (ML) has recently emerged as a powerful tool that can predict a...
Marine Bioactive Peptides in the Regulation of Inflammatory Responses: Current Trends and Future Directions [0.03%]
海洋生物活性肽在调控炎症反应中的作用：现状与未来展望
D M N M Gunasekara,H D T U Wijerathne,Lei Wang et al.
D M N M Gunasekara et al.
Marine-derived bioactive peptides (MBPs) are emerging as promising natural agents for regulating inflammatory responses. MBPs, typically obtained through enzymatic hydrolysis of proteins from various marine organisms such as fish, mollusks,...
Temporal and Spatial Profiling of Escherichia coli O157:H7 Surface Proteome: Insights into Intestinal Colonisation Dynamics In Vivo [0.03%]
鼠源大肠杆菌O157:H7菌体表面蛋白组的时空分析及其黏附定植机制研究
Ricardo Monteiro,Ingrid Chafsey,Charlotte Cordonnier et al.
Ricardo Monteiro et al.
Background: EHEC O157:H7 causes severe gastrointestinal illness by first colonizing the large intestine. It intimately attaches to the epithelial lining, orchestrating distinctive "attaching and effacing" lesions that dis...
Protein-Predicted Obesity Phenotypes and Cardiovascular Events: A Secondary Analysis of UK Biobank Proteomics Data [0.03%]
基于英国生物样本库蛋白质组学数据的肥胖表型与心血管事件的关联研究
Chang Liu,Bojung Seo,Qin Hui et al.
Chang Liu et al.
Background: Proteomic profiling may improve the understanding of obesity and cardiovascular risk prediction. This study explores the use of protein-predicted scores for body mass index (PPSBMI), body fat percentage (PPSBF...
Protein Structural Modeling Explains Rapid Oxidation in Poultry and Fish Myoglobins Compared to Livestock Myoglobins [0.03%]
蛋白质结构模型解释了家禽和鱼类肌红蛋白与哺乳动物肌红蛋白相比快速氧化的原因
Greeshma Sreejesh,Surendranath P Suman,Gretchen G Mafi et al.
Greeshma Sreejesh et al.
Background: This study aimed to investigate rapid oxidation in poultry and fish myoglobin compared to livestock myoglobin using protein structural differences and bioinformatics tools. ...
Extracellular Vesicle (EV) Proteomics in Corneal Regenerative Medicine [0.03%]
角膜再生医学中的细胞外囊泡（EV）蛋白质组学研究
Zohreh Arabpour,Hanieh Niktinat,Firouze Hatami et al.
Zohreh Arabpour et al.
Corneal regeneration has gained growing interest in recent years, largely due to the limitations of conventional treatments and the persistent shortage of donor tissue. Among the emerging strategies, extracellular vehicles (EVs), especially...