Peptidomic Analysis Reveals Temperature-Dependent Proteolysis in Rainbow Trout (Oncorhynchus mykiss) Meat During Sous-Vide Cooking [0.03%]
蛋白质组学分析揭示了在真空低温烹饪过程中虹鳟肉中的温度依赖性蛋白水解作用
Miyu Sakuyama,Yuri Kominami,Hideki Ushio
Miyu Sakuyama
Sous vide, a cooking method that involves vacuum-sealed fish at low temperatures, yields a uniquely tender, easily flaked texture. Previous research on sous-vide tenderization has focused on thermal protein denaturation. On the other hand, ...
The Non-Linear Profile of Aging: U-Shaped Expression of Myostatin, Follistatin and Intermediate Signals in a Longitudinal In Vitro Murine Cell Sarcopenia Model [0.03%]
非线性的衰老进程：慢病毒介导的肌肉干细胞原位注射治疗杜氏肌营养不良症的小鼠实验研究
Janire Alonso-Puyo,Oihane Izagirre-Fernandez,Olatz Crende et al.
Janire Alonso-Puyo et al.
Sarcopenia is linked to the decline in muscle mass, strength and function during aging. It affects the quality and life expectancy and can lead to dependence. The biological process underlying sarcopenia is unclear, but the proteins myostat...
Assessment of Data-Independent Acquisition Mass Spectrometry (DIA-MS) for the Identification of Single Amino Acid Variants [0.03%]
数据非依赖性采集质谱(DIA-MS)鉴定单氨基酸变异的评估研究
Ivo Fierro-Monti,Klemens Fröhlich,Christian Schori et al.
Ivo Fierro-Monti et al.
Proteogenomics integrates genomic and proteomic data to elucidate cellular processes by identifying variant peptides, including single amino acid variants (SAAVs). In this study, we assessed the capability of data-independent acquisition ma...
Transcriptomics Revealed Differentially Expressed Transcription Factors and MicroRNAs in Human Diabetic Foot Ulcers [0.03%]
转录组学揭示了人糖尿病足溃疡中差异表达的转录因子和microRNA
Vikrant Rai
Vikrant Rai
Non-healing diabetic foot ulcers (DFUs) not only significantly increase morbidity and mortality but also cost a lot and drain healthcare resources. Persistent inflammation, decreased angiogenesis, and altered extracellular matrix remodeling...
Comparative Proteome-Wide Abundance Profiling of Yeast Strains Deleted for Cdc48 Adaptors [0.03%]
cdc48适配体缺失酵母菌株的蛋白质组定量分析
Valentina Rossio,Joao A Paulo
Valentina Rossio
The yeast ATPase Cdc48 (known as p97/VCP in human cells) plays an important role in the Ubiquitin Proteasome System. VCP is essential for cancer cell proliferation, and its dysregulation has been implicated in several neurodegenerative dise...
Multiple Reaction Monitoring-Mass Spectrometric Immunoassay Analysis of Parathyroid Hormone Fragments with Vitamin D Deficiency in Patients with Diabetes Mellitus [0.03%]
糖尿病合并维生素D缺乏患者甲状旁腺素片段的多重反应监测-质谱免疫分析
Hicham Benabdelkamel,Refat M Nimer,Afshan Masood et al.
Hicham Benabdelkamel et al.
Current immunoassay techniques for analyzing clinically relevant parathyroid hormone (PTH) circulating fragments cannot distinguish microheterogeneity among structurally similar molecular species. This hinders the identification of molecula...
Circulating Factors as Potential Biomarkers of Cardiovascular Damage Progression Associated with Type 2 Diabetes [0.03%]
与2型糖尿病相关的心血管损伤进展的循环因子潜在生物标志物研究
Giovanni Sartore,Francesco Piarulli,Eugenio Ragazzi et al.
Giovanni Sartore et al.
Background: Diabetes, particularly type 2 diabetes (T2D), is linked with an increased risk of developing coronary heart disease (CHD). The present study aimed to evaluate potential circulating biomarkers of CHD by adopting a targeted proteo...
Towards Characterization of Hass Avocado Peel and Pulp Proteome during Postharvest Shelf Life [0.03%]
霍斯牛油果收获后货架期内果皮和果肉蛋白组分的变化特征分析
Carolina Camacho-Vázquez,José Miguel Elizalde-Contreras,Francisco Antonio Reyes-Soria et al.
Carolina Camacho-Vázquez et al.
In recent years, avocados have gained worldwide popularity as a nutritive food. This trend is causing a rise in the production of this fruit, which is accompanied by several problems associated with monocultural practices. Despite massive e...
Protein Extraction Methods Suitable for Muscle Tissue Proteomic Analysis [0.03%]
适用于肌肉组织蛋白组分析的蛋白质提取方法
Lorenza Vantaggiato,Claudia Landi,Enxhi Shaba et al.
Lorenza Vantaggiato et al.
Muscle tissue is one of the most dynamic and plastic tissues of the mammalian body and covers different roles, such as force generation and metabolic control. Muscular proteomics provides an important opportunity to reveal the molecular mec...
Katarina Vrbnjak,Raj Nayan Sewduth
Katarina Vrbnjak
Despite the advances in modern cancer therapy, malignant diseases are still a leading cause of morbidity and mortality worldwide. Conventional treatment methods frequently lead to side effects and drug resistance in patients, highlighting t...