Mechanism of Atractylenolide Ⅲ alleviating pyrotinib-induced diarrhea by regulating AMPK/CFTR pathway through metabolite of gut microbiota [0.03%]
肠道微生物代谢物通过调节AMPK/CFTR通路缓解吡柔比星诱导的腹泻的作用机制研究
Fengxian Jiang,Pancen Ran,Liyin Pan et al.
Fengxian Jiang et al.
Atractylenolide III, a sesquiterpene extracted from the rhizome of Atractylodes macrocephala (Asteraceae), exhibits pharmacological effects, including improvement of gastrointestinal function, regulation of immune function, anti-inflammator...
Auricular acupuncture plays a neuroprotective role in 6-hydroxydopamine-induced Parkinson's disease in rats [0.03%]
耳部针灸在6-羟基多巴胺诱导的帕金森病大鼠模型中具有神经保护作用
Huong Thi-Mai Nguyen,Der-Yen Lee,Ching-Liang Hsieh
Huong Thi-Mai Nguyen
Background: Parkinson's disease (PD) is the second-most common neurodegenerative disease. Currently, PD treatment is symptomatic and involves the use of dopamine-based therapies. This study investigated auricular acupunct...
Traditional Chinese medicine as a protective strategy against chemotherapy-induced cardiotoxicity: An overview of the literature [0.03%]
中药作为防止化疗引起的心脏毒性的保护策略：文献综述
Jun-Wei Wang,Hong Shao,You-Ni Zhang et al.
Jun-Wei Wang et al.
Cardiotoxicity refers to the damage caused to the heart or vascular system, which has become a significant cause of morbidity and mortality worldwide. Up to 20 % of adults undergoing cancer treatment may experience cardiotoxicity, with 7 %-...
Crocin elicits potent anti-inflammatory and fibrinolytic properties post tendon injury, A new molecule for adhesion therapy [0.03%]
crocin具有抗炎和纤溶作用，是一种新的肌腱粘连治疗分子
Hamideh Naimi,Majid Khazaei,Fariba Sharifnia et al.
Hamideh Naimi et al.
Background: Post-surgical tendon adhesion formation is a frequent clinical complication with limited treatment options. The aim of this study is to investigate safety and efficacy of orally administration of crocin in att...
Unlocking the potential of luteolin: A natural migraine management approach through network pharmacology [0.03%]
网络药理学在天然风痛管理中的潜力：以芹菜素为例
Rapuru Rushendran,Chitra Vellapandian
Rapuru Rushendran
Background: Luteolin, a natural flavonoid, exhibits antioxidant and anti-inflammatory properties and has been investigated for potential health benefits. Its focus on migraine management arises from its ability to mitigat...
Unlocking the mechanistic potential of Thuja occidentalis for managing diabetic neuropathy and nephropathy [0.03%]
东黄松在糖尿病神经病变和肾病管理中的机制潜力探究
Shareen Singh,Thakur Gurjeet Singh
Shareen Singh
Diabetes mellitus and its debilitating microvascular complications, including diabetic neuropathy and nephropathy, represent a growing global health burden. Despite advances in conventional therapies, their suboptimal efficacy and adverse e...
Integrated skin metabolomics and network pharmacology to explore the mechanisms of Goupi Plaster for treating knee osteoarthritis [0.03%]
整合皮肤代谢组学和网络药理学探讨骨皮膏治疗膝关节炎的作用机制研究
Jia Liu,Yingpeng Li,Jiajing Wang et al.
Jia Liu et al.
Background and aim: Goupi Plaster (GP) is topical traditional Chinese medicine preparation. It has been used to treat Knee Osteoarthritis (KOA) in clinical practice of traditional Chinese medicine (TCM). However, the mech...
Exploring the ROS-mediated anti-cancer potential in human triple-negative breast cancer by garlic bulb extract: A source of therapeutically active compounds [0.03%]
探究大蒜提取物通过ROS介导的抗癌潜力在人类三阴性乳腺癌中的作用：一种治疗活性化合物的来源
Shivbrat Upadhyay,Rumana Ahmad,Raushan Kumar et al.
Shivbrat Upadhyay et al.
Background and aim: Allium sativum L. has been used medicinally and traditionally since antiquity. This study sought to examine the Allium sativum ethanolic extract (ASEE) in inducing apoptosis in human triple-negative br...
Cannabidiol suppresses proliferation and induces cell death, autophagy and senescence in human cholangiocarcinoma cells via the PI3K/AKT/mTOR pathway [0.03%]
大麻二酚通过PI3K / AKT / mTOR途径抑制人胆管癌细胞的增殖并诱导凋亡，自噬和衰老
Thatsanapong Pongking,Kitti Intuyod,Phonpilas Thongpon et al.
Thatsanapong Pongking et al.
Background and aim: Cholangiocarcinoma (CCA) is usually diagnosed at a late stage, leading to treatment failure. Cannabidiol (CBD), exhibits diverse anti-cancer effects in various cancers, offering avenues for improving C...
In vivo evaluation of Andrographis paniculata and Boesenbergia rotunda extract activity against SARS-CoV-2 Delta variant in Golden Syrian hamsters: Potential herbal alternative for COVID-19 treatment [0.03%]
安万特草和虎杖提取物对叙利亚仓鼠中Delta变异株感染的体内评价：COVID-19潜在草药替代疗法
Supasek Kongsomros,Tussapon Boonyarattanasoonthorn,Wallaya Phongphaew et al.
Supasek Kongsomros et al.
The ongoing COVID-19 pandemic has triggered extensive research, mainly focused on identifying effective therapeutic agents, specifically those targeting highly pathogenic SARS-CoV-2 variants. This study aimed to investigate the in vivo anti...