A novel postbiotic from Lacticaseibacillus rhamnosus CRL1505 able to enhance the steady-state myelopoiesis [0.03%]
一株鼠李糖乳杆菌CRL1505后生物制剂可增强稳态髓系造血作用
Gutiérrez Florencia,Vasile Brenda,Ivir Maximiliano et al.
Gutiérrez Florencia et al.
The myelopotentiating effect of postbiotics derived from the probiotic Lacticaseibacillus rhamnosus CRL1505, including the peptidoglycan (PG1505), and the cell wall (CW1505), was evaluated in cyclophosphamide (Cy)-immunosuppressed mice. Adu...
Gancao Nourishing-Yin decoction ameliorates endothelial inflammaging induced by serum from rheumatoid arthritis patients [0.03%]
甘草养阴方药纠正类风湿关节炎患者血清诱导的内皮细胞衰老炎症反应
Yong Chen,Baojiang Wang,Yongchao Zhao et al.
Yong Chen et al.
Background and aim: Inhibiting inflammaging is key to preventing cardiovascular complications in rheumatoid arthritis (RA) patients. Gancao Nourishing-Yin decoction (GCNY), a Chinese herbal remedy, has shown anti-inflamma...
A double-blinded randomized clinical trial: Topical Sahasthara extract versus diclofenac for treating primary knee osteoarthritis using microemulsions as a topical delivery system [0.03%]
一种双盲随机临床试验：以微乳液为局部递送系统的药用植物Sahasthara提取物与氟比洛芬治疗膝关节骨性关节炎的疗效比较
Ninnart Intharit,Arunporn Itharat,Raimar Löbenberg et al.
Ninnart Intharit et al.
Background and aim: Sahasthara (SHT), a traditional Thai herbal remedy used for anti-inflammatory and musculoskeletal disorders, lacks clinical evaluation as a topical formulation employing microemulsion (ME) technology. ...
Gan-Mai-Da-Zao-Tang attenuates age-induced skeletal muscle wasting and improves mitochondrial function in mice [0.03%]
甘麦大枣汤通过改善线粒体功能缓解小鼠肌肉衰老减少肌肉衰减现象
Wan-Hsuan Chang,Yu-Fan Chuang,Po-Chien Li et al.
Wan-Hsuan Chang et al.
Background and aim: Skeletal muscle is the largest organ of the human body. It affects body metabolism and cooperates with other organs to maintain various physiological functions. Gan-Mai-Da-Zao-Tang (, gān mài dà zǎ...
Enhanced bone tissue regeneration via mesenchymal stem cells-laden Alginate/GelMa 3D-Bioprinted scaffold treated with Haplophyllum tuberculatum extract [0.03%]
Haplophyllum tuberculatum提取物处理的负载间充质干细胞的藻酸盐/明胶甲基丙烯酰胺3D生物打印支架促进骨组织再生
Fatemeh Jamshidi-Adegani,Sulaiman Al-Hashmi,Saeid Vakilian et al.
Fatemeh Jamshidi-Adegani et al.
Background and aim: Regeneration of critical-sized bone defects is challenging due to avascular necrosis, inflammation, and disrupted osteogenesis. This study explores the synergistic effects of Haplophyllum tuberculatum ...
Combination therapy of shinbaro and celecoxib improves joint pain and cartilage degradation in an osteoarthritis mouse model [0.03%]
信巴罗与塞来昔布联合治疗可改善骨关节炎小鼠模型的关节疼痛和软骨退变
Jae-Hwan Jang,Yurim Song,Seok Hee Han et al.
Jae-Hwan Jang et al.
Osteoarthritis is characterized by cartilage degeneration and joint pain, and celecoxib is widely used to treat osteoarthritis, but it has the risk of side effects. We investigated the effect of Shinbaro, a herbal medicine, combined with ce...
Spatholobus suberectus Dunn inhibits breast cancer bone metastasis in vitro and in vivo [0.03%]
碎骨素藤茎提取物通过内吞作用抑制乳腺癌骨转移
Qingqing Liu,Nanxi Li,Dijie Li et al.
Qingqing Liu et al.
Background and aim: Breast cancer bone metastasis (BCBM) has a high incidence in clinical settings, resulting in decreased life expectancy and quality of life. Previous research has shown that Spatholobus suberectus Dunn ...
Inhibitory effect of standardized Kaempferia parviflora extract on sarcopenia by improving protein metabolism pathways in aged C57BL/6J mice [0.03%]
万代兰提取物通过改善老化小鼠蛋白代谢通路抑制肌少症的作用机制研究
Changhee Kim,Minseong Kang,Yeeun Kim et al.
Changhee Kim et al.
Background: Sarcopenia is a muscle disease typically characterized by an age-related loss of muscle mass and function, leading to the deterioration of health in older adults. The current study aimed to investigate the the...
Damage-induced muscle regeneration after exercise in humans: Modulatory effects of ginsenoside Rg1 [0.03%]
损伤后运动诱导的肌肉再生：人参皂苷Rg1调节效应
Andrew Mark Edwards,Peggy Pui Lai Or,Chien-Wen Hou et al.
Andrew Mark Edwards et al.
Exercise-induced focal sarcolemmal disruption in susceptible myofibers results in bone marrow cell infiltration and reduced cellular senescence in skeletal muscle, followed by increases in muscle strength and mass. In contrast, removal of g...
Geniposide activates the transcription of Ndufs8 and enhances PD-L1 blockade for inhibiting growth of osteosarcoma [0.03%]
金诺芬通过激活Ndufs8转录和增强PD-L1抑制作用来抑制成骨肉瘤生长
Fanghao Zheng,Tingting Zhao,Zhenyang Liu et al.
Fanghao Zheng et al.
Geniposide, a key bioactive component of Gardenia jasminoides, is an iridoid glycoside known for its therapeutic potential in various diseases characterized by oxidative stress or inflammation, including atherosclerosis, brain disorders, an...