Antiosteoporotic activity of nodakenetin, a coumarin compound from Angelica decursiva, by activation of the Wnt/β-catenin signaling pathway [0.03%]
当归素丁通过激活Wnt/β-连环蛋白信号通路抗骨质疏松作用研究
Eun Ju Jeong,Jayoung Song,Hyen Joo Park et al.
Eun Ju Jeong et al.
Angelica decursiva (Umbelliferae) is a medicinal plant widely used to treat colds, coughs and fevers in Korea, Japan, and mainland China. The anti-inflammatory activity of nodakenetin, a furano-coumarin compound from A. decursiva, has been ...
Treatment of allergic rhinitis with a mixed Chinese herbal formula via regulatory B cells: A prospective pilot study [0.03%]
基于调节性B细胞对过敏性鼻炎进行中药复方干预的前瞻性研究
Pei-Yu Hsu,Yi-Chiu Li,Jung-Chun Chiu et al.
Pei-Yu Hsu et al.
Background and aim: Mixed Chinese herbal formulas (CHFs) are commonly prescribed for allergic rhinitis (AR), but few studies explore their mechanisms. Prior research highlighted the immunomodulatory effects of a specific ...
Integration of transcriptomics and metabolomics to study the mechanism of Siwei Huangqi powder in Tibetan medicine for protecting against high-altitude hypoxic brain injuries [0.03%]
整合转录组学和代谢组学研究藏药司伟黄芪粉防治高原缺氧性脑损伤的作用机制
Wangjie Cao,Jiawang Guo,Nengxian Zhang et al.
Wangjie Cao et al.
Background and aim: Siwei Huangqi powder (SWHQP) is a folk medicine that is extensively used in Tibetan medicine. It is widely employed at the medical institutions of various monasteries in the Tibetan region and is highl...
Anti-inflammatory and antinociceptive effects of Aloysia gratissima leaves essential oil: An in vivo study [0.03%]
Aloysia gratissima叶精油的抗炎和镇痛作用：体内研究
Maryelen A Souza,Ketelin Kunh,Otávio Sanaiotto et al.
Maryelen A Souza et al.
Background and aim: Aloysia gratissima is used in popular medicine as an analgesic and sedative. However, studies on its biological activities are still scarce. Therefore, this work aimed to evaluate the antinociceptive a...
Parthenolide alleviates doxorubicin-induced cardiotoxicity via regulation of Cyp1a1 and Nppa and suppression of NLRP3 inflammasome [0.03%]
帕烯醇通过调节细胞色素P450 1A1和心钠素的表达及抑制NLRP3炎性小体减轻阿霉素的心脏毒性作用
Yuanying Yang,Shanshan Wei,Sa Liu et al.
Yuanying Yang et al.
Background and aim: Doxorubicin (Dox) has limited clinical use due to its multiple adverse reactions, typically severe cardiotoxicity. Parthenolide (PTL) is the main active ingredient extracted from the buds of Tanacetum ...
Polysaccharides derived from alkali-extracted vinegar-baked Radix Bupleuri suppress hyperimmune T lymphocytes and ameliorate skin graft rejection [0.03%]
碱液提取醋制柴胡多糖抑制超敏T淋巴细胞并改善皮肤移植物排斥反应
Ya Zhao,Ni Wei,Zhifen Liu et al.
Ya Zhao et al.
Background: New immunosuppressants with good efficacy and high safety are urgently needed to address immune rejection following organ transplantation. The study aimed to investigate the effect of alkali-extracted vinegar-...
Integrated lipidomics and network pharmacology analysis to determine how Gu Fu Sheng Capsule improves lipid metabolism in rats with steroid-induced osteonecrosis of the femoral head [0.03%]
整合脂质组学和网络药理学分析探讨骨肽胶囊改善糖皮质激素致股骨头坏死模型大鼠脂代谢的作用机制研究
Yue Li,Ying Liu,Yingchun Li et al.
Yue Li et al.
Background: Steroid-induced osteonecrosis of the femoral head (SONFH) is a prevalent refractory condition in orthopedics, often causing high disability rates. Gu Fu Sheng Capsule (GFSC) is commonly used to treat SONFH dur...
Isoliquiritigenin: A natural compound with a promising role in inhibiting breast cancer lung metastasis [0.03%]
异甘草素：一种有望在抑制乳腺癌肺转移中发挥作用的天然化合物
Kumar Ganesan,Cong Xu,Bing Du et al.
Kumar Ganesan et al.
Background and aim: Isoliquiritigenin (ISL) is a dietary bioactive compound that is derived from the roots of licorice and various other plants. Accumulating evidence suggests that ISL has noteworthy anticancer activity i...
Scalp and auricular acupuncture attenuate recurrent gastroesophageal reflux disease and related inflammatory cytokines [0.03%]
头皮和耳针减轻胃食管反流病及其相关炎症细胞因子水平的复发
Tsung-Kai Wen,Sheng-Jie Shiue,Yuan-Ju Huang et al.
Tsung-Kai Wen et al.
Background: Gastroesophageal reflux disease (GERD) is increasingly common in developed countries. The pathogenesis involved in the symptoms includes gastric acid, esophageal or gastric motility disorders, visceral hyperse...
Evaluating the antiviral efficacy and specificity of chlorogenic acid and related herbal extracts against SARS-CoV-2 variants via spike protein binding intervention [0.03%]
通过刺突蛋白结合干预评估氯ogenic酸和相关草药提取物对SARS-CoV-2变异株的抗病毒功效和特异性
Wen-Yu Hsieh,Chu-Nien Yu,Chang-Chang Chen et al.
Wen-Yu Hsieh et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus infect the respiratory tract through surface proteins, causing similar symptoms. Since the onset of the COVID-19 pandemic, both viruses have posed significan...