Evolution and Spatiotemporal Expression of ankha and ankhb in Zebrafish [0.03%]
斑马鱼ankha和ankhb基因的进化及其时空表达模式研究
Nuwanthika Wathuliyadde,Katherine E Willmore,Gregory M Kelly
Nuwanthika Wathuliyadde
Craniometaphyseal Dysplasia (CMD) is a rare skeletal disorder that can result from mutations in the ANKH gene. This gene encodes progressive anksylosis (ANK), which is responsible for transporting inorganic pyrophosphate (PPi) and ATP from ...
Anna Fazzio,Angela Caponnetto,Carmen Ferrara et al.
Anna Fazzio et al.
Extracellular vesicles represent a large heterogeneous class of near and long-distance intercellular communication mediators, released by both prokaryotic and eukaryotic cells. Specifically, the scientific community has shown growing intere...
Lowered GnT-I Activity Decreases Complex-Type N-Glycan Amounts and Results in an Aberrant Primary Motor Neuron Structure in the Spinal Cord [0.03%]
GnT-I活性降低减少复杂N-聚糖的数量并导致脊髓中初级运动神经元结构异常
Cody J Hatchett,M Kristen Hall,Abel R Messer et al.
Cody J Hatchett et al.
The attachment of sugar to proteins and lipids is a basic modification needed for organismal survival, and perturbations in glycosylation cause severe developmental and neurological difficulties. Here, we investigated the neurological conse...
Canonical and Non-Canonical Wnt Signaling Generates Molecular and Cellular Asymmetries to Establish Embryonic Axes [0.03%]
规范和非规范Wnt信号通路由建立分子和细胞不对称性来确立胚胎轴
De-Li Shi
De-Li Shi
The formation of embryonic axes is a critical step during animal development, which contributes to establishing the basic body plan in each particular organism. Wnt signaling pathways play pivotal roles in this fundamental process. Canonica...
Genes Related to Frontonasal Malformations Are Regulated by miR-338-5p, miR-653-5p, and miR-374-5p in O9-1 Cells [0.03%]
微RNAs miR-338-5p、miR-653-5p 和 miR-374-5p调控与前额鼻畸形相关的基因在O9-1细胞中
Chihiro Iwaya,Sunny Yu,Junichi Iwata
Chihiro Iwaya
Frontonasal malformations are caused by a failure in the growth of the frontonasal prominence during development. Although genetic studies have identified genes that are crucial for frontonasal development, it remains largely unknown how th...
Getting to the Core: Exploring the Embryonic Development from Notochord to Nucleus Pulposus [0.03%]
追本溯源：从胚胎发育角度探秘软骨终板和椎间盘髓核的关系及功能
Luca Ambrosio,Jordy Schol,Clara Ruiz-Fernández et al.
Luca Ambrosio et al.
The intervertebral disc (IVD) is the largest avascular organ of the human body and plays a fundamental role in providing the spine with its unique structural and biomechanical functions. The inner part of the IVD contains the nucleus pulpos...
Rho-Associated Protein Kinase Activity Is Required for Tissue Homeostasis in the Xenopus laevis Ciliated Epithelium [0.03%]
Rho相关蛋白激酶活性对非洲爪蟾纤毛上皮组织稳态是必需的
Fayhaa Khan,Lenore Pitstick,Jessica Lara et al.
Fayhaa Khan et al.
Lung epithelial development relies on the proper balance of cell proliferation and differentiation to maintain homeostasis. When this balance is disturbed, it can lead to diseases like cancer, where cells undergo hyperproliferation and then...
Harderian Gland Development and Degeneration in the Fgf10-Deficient Heterozygous Mouse [0.03%]
FGF10缺陷杂合小鼠的_HARDERIAN_腺发育及退化现象
Shiori Ikeda,Keita Sato,Hirofumi Fujita et al.
Shiori Ikeda et al.
The mouse Harderian gland (HG) is a secretory gland that covers the posterior portion of the eyeball, opening at the base of the nictitating membrane. The HG serves to protect the eye surface from infection with its secretions. Mice open th...
Nicholas S Tolwinski
Nicholas S Tolwinski
In this Special Issue, titled "Drosophila-A Model System for Developmental Biology", we present a series of articles and reviews looking at the diverse ways that researchers are using the humble fruit fly, also known as the vinegar fly, to ...
Emerging Contributions of Pluripotent Stem Cells to Reproductive Technologies in Veterinary Medicine [0.03%]
诱导多能干细胞在兽医繁殖技术中的应用及其展望
Raiane Cristina Fratini de Castro,Tiago William Buranello,Kaiana Recchia et al.
Raiane Cristina Fratini de Castro et al.
The generation of mature gametes and competent embryos in vitro from pluripotent stem cells has been successfully achieved in a few species, mainly in mice, with recent advances in humans and scarce preliminary reports in other domestic spe...