The Association Between the Progressive Motility of Bovine Spermatozoa and the Developmental Morphokinetics of In Vitro-Derived Embryos [0.03%]
bulls精子运动的渐进性与体外胚胎发育形态动力学之间的关系
Shir Maizus,Dorit Kalo,Tanya Kogan et al.
Shir Maizus et al.
The proportion of spermatozoa with progressive motility is widely used to evaluate the quality of a single ejaculate. However, the cellular and physiological mechanisms underlying this trait remain unclear. The present study examined the as...
Expression and Role of Colony Stimulating Factor 1 Receptor During Odontogenesis [0.03%]
成釉过程中的集落刺激因子1受体的表达及其作用
Ashina Nagra,Ling-Yi Chen,Soheil Saeidiborojeni et al.
Ashina Nagra et al.
In osteopetrotic mice with homozygous inactivating mutations in the colony stimulating factor 1 (Csf1op/op) or its receptor (Csf1r-/-) gene, teeth fail to erupt due to severe reduction in osteoclastogenesis. Dental abnormalities have been d...
Functional and Genetic Analyses Unveil the Implication of hoxa4a in Zebrafish Craniofacial Development [0.03%]
功能和基因分析揭示了hoxa4a在斑马鱼颜面发育中的作用
Le Sun,Lu Ping,Fuyu Zhang et al.
Le Sun et al.
Microtia-atresia is a rare craniofacial malformation primarily affecting the first and second pharyngeal arches, leading to the deformity of the auricle and atresia of the external ear canal. Its etiology is heterogenous and largely unknown...
Torpor-Induced Regulation of Poly(A) Tail Machinery in 13-Lined Ground Squirrel Brown Adipose Tissue [0.03%]
十三纹地松鼠褐色脂肪组织中 torpor 引发的 Poly(A) 尾部机器调节现象
Saif Rehman,William G Willmore,Kenneth B Storey
Saif Rehman
The poly(A) tail has long been known to play a central role in mRNA stability, storage, and translational competence, making it a potential key regulator during hypometabolic states. During seasonal torpor, hibernating mammals must frequent...
Adenosine Receptor Functionality and Desensitization Machinery in a Neuronal Cell Model of Angelman Syndrome [0.03%]
安格曼综合征神经细胞模型中的腺苷受体功能和脱敏机制
Martina Contestabile,Jacqueline Fátima Martins de Almeida,Chiara De Cesari et al.
Martina Contestabile et al.
Angelman syndrome (AS) is a neurodevelopmental disorder caused by the loss of maternal UBE3A expression, leading to disrupted proteostasis and synaptic dysfunction. Adenosine is a ubiquitous neuromodulator whose G protein-coupled receptors ...
Fetal-Fetal and Fetal-Maternal Microchimerism: Insights from Mammalian Placental Biology [0.03%]
胎盘屏障的双重作用：胎体和母体微嵌合现象的新视角
Jorge A De Los Santos Funes
Jorge A De Los Santos Funes
Feto-maternal microchimerism (Mc) refers to the exchange of cells between the fetus and mother, and fetal-fetal Mc to the exchange between fetuses during pregnancy. This phenomenon occurs across mammalian species, including humans, mice, an...
Melatonin Receptor 1 and Melatonin Receptor 2 Expression During Human Kidney Development and Their Association with CAKUT [0.03%]
人肾脏发育过程中褪黑素受体1和褪黑素受体2的表达及其与CAKUT的关系
Ann-Kathrin Schmitt,Victoria Tjora,Nela Kelam et al.
Ann-Kathrin Schmitt et al.
Background/objectives: Growing evidence indicates that melatonin contributes to kidney development and function, while disruptions of fetal circadian signaling have been linked to congenital anomalies of the kidney and ur...
Novel Functions and Potential of Ribosomes: From Cellular Transdifferentiation to Applications in Cell-Cultured Foods [0.03%]
新颖的核糖体功能及其潜在作用：从细胞转分化到培养肉应用
Shota Inoue,Hiroaki Hatano,Ikko Kawashima et al.
Shota Inoue et al.
Ribosomes are widely recognized as large intracellular macromolecular complexes responsible for protein synthesis. However, in recent years, numerous studies have revealed that ribosomal proteins possess non-canonical functions beyond trans...
Conserved Metanephric Kidney Development and Genome Methylation in Red-Eared Slider Turtle (Trachemys scripta elegans) [0.03%]
红耳滑龟（Trachemys scripta elegans）肾脏发育及基因组甲基化规律的保守性研究
Bing Jia,Mohamed Milad,Hannah C Boehler et al.
Bing Jia et al.
Mammals and reptiles possess a metanephric kidney as the terminal renal organ for homeostasis of solutes and waste products. The development of the metanephric kidney has primarily been studied in mammalian model systems. Little is known ab...
Compensatory Serotonin Synthesis and Histone H3 Serotonylation in Preimplantation Embryos Exposed to Maternal Fluoxetine or Monoamine Oxidase Blockade [0.03%]
母体氟西汀或单胺氧化酶抑制暴露下的胚胎期补偿性血清素合成及组蛋白H3的5-羟色胺化作用机制研究
Veronika S Frolova,Denis A Nikishin
Veronika S Frolova
Serotonin is a critical morphogen in early development, yet the mechanisms regulating its homeostasis in the preimplantation embryo remain unclear, particularly under conditions of maternal antidepressant exposure. Here, we investigated emb...