Rajalakshmi Ramamoorthy,Arianna K Carden,Hussain Hussain et al.
Rajalakshmi Ramamoorthy et al.
Glucagon-like peptide 1 (GLP-1), a hormone derived from the proglucagon gene, regulates various physiological processes; however, its impact on pregnancy outcomes remains poorly understood. Assessing the effects of GLP-1 on neonates is vita...
The Congenital Malformation of the Interatrial Septum-A Review of Its Development and Embryology with Clinical Implications [0.03%]
卵隔先天性畸形-其发展与胚胎学的回顾及其临床意义
Rui Caetano Oliveira,Paula Martins,Maria de Fátima Martins
Rui Caetano Oliveira
The development process of the heart and cardiovascular system is fundamental in human development and highly regulated by genetic factors. This process needs to be highly regulated to prevent malformations. Nevertheless, some heart defects...
Evolution of the Jawed Vertebrate (Gnathostomata) Stomach Through Gene Repertoire Loss: Findings from Agastric Species [0.03%]
无胃脊椎动物（有颌脊索动物）胃的演化是通过基因组中的基因丢失实现的：来自无胃物种的证据
Jackson Dann,Frank Grützner
Jackson Dann
The stomach has been a highly conserved organ throughout vertebrate evolution; however, there are now over 20 lineages composed of monotremes, lungfish and teleost fish displaying a secondary loss of stomach function and morphology. This "a...
Identification and Characterization of Static Craniofacial Defects in Pre-Metamorphic Xenopus laevis Tadpoles [0.03%]
非洲爪蟾胚胎期蝌蚪静态颅面缺陷的识别与特征分析
Emilie Jones,Jay Miguel Fonticella,Kelly A McLaughlin
Emilie Jones
Craniofacial development is a complex, highly conserved process involving multiple tissue types and molecular pathways, with perturbations resulting in congenital defects that often require invasive surgical interventions to correct. Remark...
Deletion of Ptpmt1 by αMHC-Cre in Mice Results in Left Ventricular Non-Compaction [0.03%]
小鼠αMHC-Cre删除Ptpmt1致左心室非 compaction 病理形成
Lei Huang,Maowu Cao,Xiangbin Zhu et al.
Lei Huang et al.
Background: Left ventricular non-compaction cardiomyopathy (LVNC) is a congenital heart disease characterized by abnormal prenatal development of the left ventricle that has an aberrantly thick trabecular layer and a thinner compacted myoca...
Is Hydra Axis Definition a Fluctuation-Based Process Picking Up External Cues? [0.03%]
水熊虫轴向定义是一个基于波动的、接收外部线索的过程吗？
Mikhail A Zhukovsky,Si-Eun Sung,Albrecht Ott
Mikhail A Zhukovsky
Axis definition plays a key role in the establishment of animal body plans, both in normal development and regeneration. The cnidarian Hydra can re-establish its simple body plan when regenerating from a random cell aggregate or a sufficien...
HP1-Mediated Silencing of the Doublesex1 Gene for Female Determination in the Crustacean Daphnia magna [0.03%]
甲壳动物大型水蚤通过HP1介导的Doublesex1基因沉默决定雌性性别
Junya Leim,Nikko Adhitama,Quang Dang Nong et al.
Junya Leim et al.
The crustacean Daphnia magna produces genetically identical females and males by parthenogenesis. Males are produced in response to environmental cues including crowding and lack of food. For male development, the DM-domain containing trans...
Investigating Psychopharmaceutical Effects on Early Vertebrate Development Using a Zebrafish Model System [0.03%]
采用斑马鱼模型系统研究 psychopharmaceutical 对早期脊椎动物发育的影响
Nathan Zimmerman,Aaron Marta,Carly Baker et al.
Nathan Zimmerman et al.
Cholesterol homeostasis is necessary for normal vertebrate development. The disruption of cholesterol homeostasis can cause abnormal body and nervous system development and lead to dysfunctional behavior and increased mortality. Commonly pr...
Drosophila Males Differentially Express Small Proteins Regulating Stem Cell Division Frequency in Response to Mating [0.03%]
果蝇雄性根据交配情况差异表达调控干细胞分裂频率的小蛋白
Manashree S Malpe,Leon F McSwain,Heath M Aston et al.
Manashree S Malpe et al.
The germline stem cells (GSCs) in the male gonad of Drosophila can increase their division frequency in response to a demand for more sperm caused by repeated mating. However, the molecules and mechanisms regulating and mediating this respo...
Cannabinoid Receptor 1 Regulates Zebrafish Renal Multiciliated Cell Development via cAMP Signaling [0.03%]
大麻素受体1通过cAMP信号通路调节斑马鱼肾纤毛细胞发育
Thanh Khoa Nguyen,Sophia Baker,Julienne Angtuaco et al.
Thanh Khoa Nguyen et al.
Endocannabinoid signaling plays a significant role in neurogenesis and nervous system physiology, but its roles in the development of other tissues are just beginning to be appreciated. Previous reports have shown the presence of the key en...