Hermes (Rbpms) is a Critical Component of RNP Complexes that Sequester Germline RNAs during Oogenesis [0.03%]
赫尔墨斯(RBPMS)是卵母细胞发生过程中固定生殖细胞RNA的RNP复合体的关键组成部分
Tristan Aguero,Yi Zhou,Malgorzata Kloc et al.
Tristan Aguero et al.
The germ cell lineage in Xenopus is specified by the inheritance of germ plasm that assembles within the mitochondrial cloud or Balbiani body in stage I oocytes. Specific RNAs, such as nanos1, localize to the germ plasm. nanos1 has the esse...
Restricted Pax3 Deletion within the Neural Tube Results in Congenital Hydrocephalus [0.03%]
神经管内受限制的Pax3基因缺失导致先天性脑积水
Hong-Ming Zhou,Simon J Conway
Hong-Ming Zhou
Congenital hydrocephalus is a common birth-defect whose developmental origins are poorly understood. Pax3-null mutants show defects in myogenesis, neural tube closure, neural crest morphogenesis, and heart development that, consequently, re...
Evan B Dewey,Danielle T Taylor,Christopher A Johnston
Evan B Dewey
The ability to dictate cell fate decisions is critical during animal development. Moreover, faithful execution of this process ensures proper tissue homeostasis throughout adulthood, whereas defects in the molecular machinery involved may c...
Anthony Hafez,Ryan Squires,Amber Pedracini et al.
Anthony Hafez et al.
Collagen XI alpha 1 (Col11a1) is an extracellular matrix molecule required for embryonic development with a role in both nucleating the formation of fibrils and regulating the diameter of heterotypic fibrils during collagen fibrillar assemb...
Pbx4 is Required for the Temporal Onset of Zebrafish Myocardial Differentiation [0.03%]
Pbx4是斑马鱼心肌细胞分化的必需因子
Robert M Kao,Joel G Rurik,Gist H Farr rd et al.
Robert M Kao et al.
Proper control of the temporal onset of cellular differentiation is critical for regulating cell lineage decisions and morphogenesis during development. Pbx homeodomain transcription factors have emerged as important regulators of cellular ...
Peter Hofsteen,Jessica Plavicki,Richard E Peterson et al.
Peter Hofsteen et al.
Zebrafish (Danio rerio) are an excellent vertebrate model for studying heart development, regeneration and cardiotoxicity. Zebrafish embryos exposed during the temporal window of epicardium development to the aryl hydrocarbon receptor (AHR)...
Marina Peralta,Juan Manuel González-Rosa,Inês Joao Marques et al.
Marina Peralta et al.
The epicardium is the mesothelial outer layer of the vertebrate heart. It plays an important role during cardiac development by, among other functions, nourishing the underlying myocardium, contributing to cardiac fibroblasts and giving ris...
The Epicardium and the Development of the Atrioventricular Junction in the Murine Heart [0.03%]
小鼠心脏 epicardium 和房室连接发育之间的关系
Marie M Lockhart,Aimee L Phelps,Maurice J B van den Hoff et al.
Marie M Lockhart et al.
Insight into the role of the epicardium in cardiac development and regeneration has significantly improved over the past ten years. This is mainly due to the increasing availability of new mouse models for the study of the epicardial lineag...
Induction of the Proepicardium [0.03%]
心前体的诱导
Lisandro Maya-Ramos,James Cleland,Michael Bressan et al.
Lisandro Maya-Ramos et al.
The proepicardium is a transient extracardiac embryonic tissue that gives rise to the epicardium and a number of coronary vascular cell lineages. This important extracardiac tissue develops through multiple steps of inductive events, from s...