Regulation of Silk Genes by Hox and Homeodomain Proteins in the Terminal Differentiated Silk Gland of the Silkworm Bombyx mori [0.03%]
家蚕Bombyx mori后肠分化期丝蛋白基因受HOX及同源异形结构域蛋白调控
Shigeharu Takiya,Takuya Tsubota,Mai Kimoto
Shigeharu Takiya
The silk gland of the silkworm Bombyx mori is a long tubular organ that is divided into several subparts along its anteroposterior (AP) axis. As a trait of terminal differentiation of the silk gland, several silk protein genes are expressed...
Developmental Mechanism of Limb Field Specification along the Anterior-Posterior Axis during Vertebrate Evolution [0.03%]
脊椎动物演化过程中前後轴肢体场分化的发育机制
Mikiko Tanaka
Mikiko Tanaka
In gnathostomes, limb buds arise from the lateral plate mesoderm at discrete positions along the body axis. Specification of these limb-forming fields can be subdivided into several steps. The lateral plate mesoderm is regionalized into the...
Functional and Comparative Genomics of Hoxa2 Gene cis-Regulatory Elements: Evidence for Evolutionary Modification of Ancestral Core Element Activity [0.03%]
Hoxa2基因顺式调控元件的功能及比较基因组分析：关于祖始核心序列活性发生进化改变的证据
Adam Davis,Michael C Reubens,Edmund J Stellwag
Adam Davis
Hoxa2 is an evolutionarily conserved developmental regulatory gene that functions to specify rhombomere (r) and pharyngeal arch (PA) identities throughout the Osteichthyes. Japanese medaka (Oryzias latipes) hoxa2a, like orthologous Hoxa2 ge...
Lucie Jeannotte,Florian Gotti,Kim Landry-Truchon
Lucie Jeannotte
A critical position in the developmental hierarchy is occupied by the Hox genes, which encode transcription factors. Hox genes are crucial in specifying regional identity along the embryonic axes and in regulating morphogenesis. In mouse, t...
Marine Roux,Stéphane Zaffran
Marine Roux
Congenital heart defects (CHD) are the leading cause of death in the first year of life. Over the past 20 years, much effort has been focused on unraveling the genetic bases of CHD. In particular, studies in human genetics coupled with thos...
Marco Barucca,Adriana Canapa,Maria Assunta Biscotti
Marco Barucca
Hox genes are regulators of animal embryonic development. Changes in the number and sequence of Hox genes as well as in their expression patterns have been related to the evolution of the body plan. Lophotrochozoa is a clade of Protostomia ...
Histologic Assessment of Drug-Eluting Grafts Related to Implantation Site [0.03%]
药物洗脱移植物的组织学评价与植入部位相关性研究
Jean-Christophe Tille,Sarra de Valence,Delia Mandracchia et al.
Jean-Christophe Tille et al.
Drug-eluting vascular prostheses represent a new direction in vascular surgery to reduce early thrombosis and late intimal hyperplasia for small calibre grafts. Subcutaneous implantation in rats is a rapid and cost-effective screening model...
João Leite-Castro,Vanessa Beviano,Pedro Nuno Rodrigues et al.
João Leite-Castro et al.
HoxA genes encode for important DNA-binding transcription factors that act during limb development, regulating primarily gene expression and, consequently, morphogenesis and skeletal differentiation. Within these genes, HoxA11 and HoxA13 we...
Zunaira Afzal,T C Howton,Yali Sun et al.
Zunaira Afzal et al.
Aquaporins are membrane channel proteins ubiquitously present in all kingdoms of life. Although aquaporins were originally discovered as water channels, their roles in the transport of small neutral solutes, gasses, and metal ions are now w...
Solving Classification Problems for Large Sets of Protein Sequences with the Example of Hox and ParaHox Proteins [0.03%]
以HOX和ParaHox蛋白为例解决大量蛋白质序列分类问题
Stefanie D Hueber,Tancred Frickey
Stefanie D Hueber
Phylogenetic methods are key to providing models for how a given protein family evolved. However, these methods run into difficulties when sequence divergence is either too low or too high. Here, we provide a case study of Hox and ParaHox p...