The Impact of Two Different Cold-Extruded Feeds and Feeding Regimens on Zebrafish Survival, Growth and Reproductive Performance [0.03%]
两种不同冷挤压饲料及投喂方案对斑马鱼存活率、生长和繁殖性能的影响
Joana F Monteiro,Sandra Martins,Matheus Farias et al.
Joana F Monteiro et al.
Zebrafish (Danio rerio) is one of the top model organisms used in biomedical research. Therefore, it is fundamental that zebrafish facilities continuously improve husbandry methods to provide fish with the best physiological and welfare con...
Tapan A Shah,Melissa B Rogers
Tapan A Shah
Crosstalk between the BMP and TGF-β signaling pathways regulates many complex developmental processes from the earliest stages of embryogenesis throughout adult life. In many situations, the two signaling pathways act reciprocally. For...
LHX2 Mediates the FGF-to-SHH Regulatory Loop during Limb Development [0.03%]
LHX2介导肢体发育过程中的FGF至SHH调控环路
Billy A Watson,Jennifer M Feenstra,Jonathan M Van Arsdale et al.
Billy A Watson et al.
During limb development, fibroblast growth factors (Fgfs) govern proximal⁻distal outgrowth and patterning. FGFs also synchronize developmental patterning between the proximal⁻distal and anterior⁻posterior axes by maintaining Sonic hedgeh...
Sonic Hedgehog Is a Member of the Hh/DD-Peptidase Family That Spans the Eukaryotic and Bacterial Domains of Life [0.03%]
音猬刺是贯穿真核生物和细菌生命领域的HH/DD-肽酶家族成员
Henk Roelink
Henk Roelink
Sonic Hedgehog (Shh) coordinates Zn2+ in a manner that resembles that of peptidases. The ability of Shh to undergo autoproteolytic processing is impaired in mutants that affect the Zn2+ coordination, while mutating residues essential for ca...
Chih-Ning Chang,Chrissa Kioussi
Chih-Ning Chang
Muscles control body movement and locomotion, posture and body position and soft tissue support. Mesoderm derived cells gives rise to 700 unique muscles in humans as a result of well-orchestrated signaling and transcriptional networks in sp...
Journal of Developmental Biology (JDB) Editorial Office
Journal of Developmental Biology (JDB) Editorial Office
The winner of the 2018 JDB Travel Award was granted to Ms. Victoria Deneke, BS, who is a fifth-year graduate student in Dr. Stefano Di Talia’s laboratory in the Department of Cell Biology at Duke University Medical Center, USA.[&helli...
Differential Cellular Responses to Hedgehog Signalling in Vertebrates-What is the Role of Competence? [0.03%]
脊椎动物对 hedgehog 信号的不同细胞反应及其作用机理
Clemens Kiecker,Anthony Graham,Malcolm Logan
Clemens Kiecker
A surprisingly small number of signalling pathways generate a plethora of cellular responses ranging from the acquisition of multiple cell fates to proliferation, differentiation, morphogenesis and cell death. These diverse responses may be...
The Many Hats of Sonic Hedgehog Signaling in Nervous System Development and Disease [0.03%]
sonic hedgehog信号在神经系统发育和疾病中的多种作用
Yesser H Belgacem,Andrew M Hamilton,Sangwoo Shim et al.
Yesser H Belgacem et al.
Sonic hedgehog (Shh) signaling occurs concurrently with the many processes that constitute nervous system development. Although Shh is mostly known for its proliferative and morphogenic action through its effects on neural stem cells and pr...
Perspectives on Intra- and Intercellular Trafficking of Hedgehog for Tissue Patterning [0.03%]
hedgehog信号在组织模式形成中的细胞内外运输的视角
Eléanor Simon,Adrián Aguirre-Tamaral,Gustavo Aguilar et al.
Eléanor Simon et al.
Intercellular communication is a fundamental process for correct tissue development. The mechanism of this process involves, among other things, the production and secretion of signaling molecules by specialized cell types and the capabilit...
Yeast Gup1(2) Proteins Are Homologues of the Hedgehog Morphogens Acyltransferases HHAT(L): Facts and Implications [0.03%]
酿酒酵母Gup1p蛋白是HHCTL(HHAT样酰基转移酶)：事实及其意义
Cândida Lucas,Célia Ferreira,Giulia Cazzanelli et al.
Cândida Lucas et al.
In multiple tissues, the Hedgehog secreted morphogen activates in the receiving cells a pathway involved in cell fate, proliferation and differentiation in the receiving cells. This pathway is particularly important during embryogenesis. Th...