Transformation of the Biological Paradigm in Bone Regeneration: An Integrative Review [0.03%]
骨再生的生物学范式转换：综合述评
Diyana Vladova
Diyana Vladova
Bone tissue is among the most commonly transplanted tissues worldwide. The treatment of critical-sized bone defects remains a significant challenge, as there is currently no universally accepted experimental model or therapeutic standard. R...
Ana Beatriz Matos,Laura Jesus Castro,Torcato Martins
Ana Beatriz Matos
Transcriptional regulation is pivotal for developmental processes and cell fate specification in homeostasis. One particularly relevant group of transcription factors is the sine oculis homeobox (SIX) family, which is involved in a wide ran...
Amalia S Parra,Christopher A Johnston
Amalia S Parra
Development and maintenance of complex tissues depends on a number of coordinated steps from early development through adulthood. These processes are fundamentally controlled by highly regulated gene expression patterns. Although critical c...
Origins of Avian Hyperactive Mitochondria, Genome Compaction, and Air-Sac Physiology in Early Theropods During the Carnian Pluvial Episode [0.03%]
鸟纲动物线粒体好动、基因组简化和气囊生理结构的早期有袋类祖先及卡尼期雨幕事件中的起源
Takumi Satoh
Takumi Satoh
Extant birds and the earliest dinosaurs may share fundamental metabolic features essential for aerobic exercise, suggesting that the extraordinary physical performance typical of avian species originated when dinosaurs first appeared during...
Evolutionary Restructuring and Systematic Review of the NBPF Gene Family: Comparative Genomics, Functional Divergence, and Disease-Linked Pathways [0.03%]
神经元丝蛋白家族的进化重塑与系统评价：比较基因组学、功能分歧及疾病相关通路
Manuel Escalona,Rosa Roy
Manuel Escalona
The Neuroblastoma Breakpoint Family (NBPF) consists of 23 genes, 9 of which are pseudogenes, and is characterized by extensive duplication events and species-specific diversification in Homo sapiens, as well as by the presence of a unique p...
The Influence of Fluidic Flow Stress on the Development of the Secondary Palate [0.03%]
流体流动应力对次生腭发育的影响
Masayo Nagata,Satoru Hayano,Ziyi Wang et al.
Masayo Nagata et al.
Craniofacial development is orchestrated by a finely regulated interplay of numerous genes and signaling pathways. Palatogenesis proceeds through a complex, stepwise process, in which endogenous mechanical stresses within tissues have been ...
Vestigial-like 4 Regulates Neurogenesis and Neural Crest Formation During Xenopus Development [0.03%]
Vestigial-like 4在非洲爪蟾发育中的神经发生和神经嵴形成中的作用
Pierre Thiébaud,Emilie Simon,François Moisan et al.
Pierre Thiébaud et al.
VESTIGIAL-LIKE proteins constitute a family of evolutionarily conserved proteins that act as cofactors in regulating gene expression through their binding to TEAD transcription factors. Among the four members of this family in vertebrates, ...
Functional State of Lampbrush Chromosomes in Early Vitellogenic Oocytes of Hibernating Frogs Rana temporaria [0.03%]
冬眠蛙Rana temporaria早中期卵母细胞lampbrush染色体的功能状态研究
Nadya V Ilicheva,Olga I Podgornaya
Nadya V Ilicheva
Lampbrush chromosomes (LBCs) are a feature of amphibian oocytes and are typically associated with high levels of transcription during active oocyte growth. However, their state during winter hibernation has not been studied. Here, we invest...
Alexey S Anisimov,Dmitry S Bogolyubov,Irina O Bogolyubova
Alexey S Anisimov
Cumulus cells (CCs) are a distinct population of granulosa cells (GCs) that surround the developing and ovulated mammalian oocyte. The features of their structural organization and the expression pattern of key genes significantly affect oo...
Influence of Obstructive Uropathy on Cyst Formation and Nephrogenesis: Insights from a Fetal Lamb Model [0.03%]
梗阻性尿路异常对膀胱发育和肾小管生成的影响：来自绵羊胎儿模型的启示
Kohei Kawaguchi,Takuya Kawaguchi,Juma Obayashi et al.
Kohei Kawaguchi et al.
Obstructive uropathy (OU) during fetal development induces a fetal cystic dysplastic kidney. The mechanisms of cyst formation and the onset of renal dysfunction remain unclear. Determining whether nephrogenic potential persists during fetal...