The Presence of Two MyoD Genes in a Subset of Acanthopterygii Fish Is Associated with a Polyserine Insert in MyoD1 [0.03%]
棘鳍鱼目中MYOD基因的双重存在与MYOD1中的聚丝氨酸插入有关
Lewis J White,Alexander J Russell,Alastair R Pizzey et al.
Lewis J White et al.
The MyoD gene was duplicated during the teleost whole genome duplication and, while a second MyoD gene (MyoD2) was subsequently lost from the genomes of some lineages (including zebrafish), many fish lineages (including Alcolapia species) h...
Reproductive-Toxicity-Related Endpoints in C. elegans Are Consistent with Reduced Concern for Dimethylarsinic Acid Exposure Relative to Inorganic Arsenic [0.03%]
与无机砷相比二甲基砷酸致线虫生殖毒性相关的终点显示较低的毒性因此降低了暴露风险
Jessica A Camacho,Bonnie Welch,Robert L Sprando et al.
Jessica A Camacho et al.
Exposures to arsenic and mercury are known to pose significant threats to human health; however, the effects specific to organic vs. inorganic forms are not fully understood. Caenorhabditis elegans' (C. elegans) transparent cuticle, along w...
Selecting Normalizers for MicroRNA RT-qPCR Expression Analysis in Murine Preimplantation Embryos and the Associated Conditioned Culture Media [0.03%]
用于小鼠着床前胚胎及其条件培养基中微小核糖核酸表达分析的标准化方法的选择
David C Hawke,Andrew J Watson,Dean H Betts
David C Hawke
Normalizing RT-qPCR miRNA datasets that encompass numerous preimplantation embryo stages requires the identification of miRNAs that may be used as stable reference genes. A need has also arisen for the normalization of the accompanying cond...
Comparison of Pronase versus Manual Dechorionation of Zebrafish Embryos for Small Molecule Treatments [0.03%]
用于斑马鱼胚胎小分子处理的Pronase与手动脱蜕膜效果比较研究
Eva H Hasegawa,Gist H Farr rd,Lisa Maves
Eva H Hasegawa
Zebrafish are a powerful animal model for small molecule screening. Small molecule treatments of zebrafish embryos usually require that the chorion, an acellular envelope enclosing the embryo, is removed in order for chemical compounds to a...
Elena Ceccacci,Emanuela Villa,Fabio Santoro et al.
Elena Ceccacci et al.
During prenatal life, the foetal liver is colonised by several waves of haematopoietic progenitors to act as the main haematopoietic organ. Single cell (sc) RNA-seq has been used to identify foetal liver cell types via their transcriptomic ...
Thanh Khoa Nguyen,Madeline Petrikas,Brooke E Chambers et al.
Thanh Khoa Nguyen et al.
Nephrons are the functional units which comprise the kidney. Each nephron contains a number of physiologically unique populations of specialized epithelial cells that are organized into discrete domains known as segments. The principles of ...
COMMD10 Is Essential for Neural Plate Development during Embryogenesis [0.03%]
COMMD10对胚胎发育过程中神经板发育是必不可少的
Khanh P Phan,Panayiotis Pelargos,Alla V Tsytsykova et al.
Khanh P Phan et al.
The COMMD (copper metabolism MURR1 domain containing) family includes ten structurally conserved proteins (COMMD1 to COMMD10) in eukaryotic multicellular organisms that are involved in a diverse array of cellular and physiological processes...
Heme Oxygenase-1 Is Upregulated during Differentiation of Keratinocytes but Its Expression Is Dispensable for Cornification of Murine Epidermis [0.03%]
血红素氧合酶-1在角质形成细胞分化过程中上调，但其表达对于小鼠表皮角化过程是不需要的
Marta Surbek,Supawadee Sukseree,Attila Placido Sachslehner et al.
Marta Surbek et al.
The epidermal barrier of mammals is initially formed during embryonic development and continuously regenerated by the differentiation and cornification of keratinocytes in postnatal life. Cornification is associated with the breakdown of or...
Hideyo Ohuchi,Tsutomu Nohno
Hideyo Ohuchi
We have assembled ten interesting manuscripts submitted by developmental biologists in Japan [...].
In Vitro Comparison of Sex-Specific Splicing Efficiencies of fem Pre-mRNA under Monoallelic and Heteroallelic Conditions of csd, a Master Sex-Determining Gene in the Honeybee [0.03%]
在定性分析雄蜂csd等位基因条件下蜜蜂fem预mRNA的性别特异性剪接效率
Yukihiro Suzuki,Takafumi Yamada,Masataka G Suzuki
Yukihiro Suzuki
The sexual fate of honeybees is determined by the complementary sex determination (CSD) model: heterozygosity at a single locus (the CSD locus) determines femaleness, while hemizygosity or homozygosity at the CSD locus determines maleness. ...