Establishment and validation of a model for predicting postoperative recurrence of sinonasal tumors based on multimodality MRI parameters [0.03%]
基于多模式MRI参数的鼻窦肿瘤术后复发预测模型的建立与验证
Fangrui Liu,Mingai You
Fangrui Liu
Background: Multimodality magnetic resonance imaging (MRI) provides a comprehensive assessment of tumor status, aiding in the prediction of postoperative recurrence. This study aimed to develop and externally validate a p...
LAPTM5-dependent lipophagy enhances ferroptosis sensitivity in glioma cells [0.03%]
LAPTM5依赖的脂噬作用可增强胶质瘤细胞铁死亡敏感性
Yan Zhang,Lu Lu,Qiuyu Zhao et al.
Yan Zhang et al.
Background: Lysosomal-associated protein transmembrane 5 (LAPTM5) is a transmembrane protein predominantly localized to late endosomes and lysosomes, with preferential expression in hematopoietic cells. Ferroptosis is an ...
A prediction model of gastric cancer based on M2-like tumor-associated macrophage infiltration verified by immunohistochemistry [0.03%]
基于M2样肿瘤相关巨噬细胞浸润的胃癌预测模型并经免疫组化验证
Li Zhang,Qin Qi,Yun Dai et al.
Li Zhang et al.
Background: Gastric cancer (GC) is known for its aggressive nature and considerable genomic diversity. M2-like tumor-associated macrophage (TAM) infiltration is closely associated with cancer progression and prognosis. Th...
Vitamin B3 suppresses RasV12 -driven tumor growth in Drosophila via redox regulation, mitochondrial function, and autophagy activation [0.03%]
维生素B3通过氧化还原调节、线粒体功能和自噬激活抑制果蝇中的RasV12驱动的肿瘤生长
Yingying Shen,Yafang Tang,Xueting Fan et al.
Yingying Shen et al.
Background: Ras-driven cancers present a major therapeutic challenge. Vitamin B3 (nicotinamide), an NAD+ precursor, shows potential anticancer activity, but its mechanisms in Ras-driven tumors require elucidation. This st...
A retrospective cohort study comparing long-term clinical outcomes between patients with and without neoadjuvant therapy in stage IB-IIB cervical cancer: a propensity score-matched study [0.03%]
新辅助治疗对各期宫颈癌患者长期临床结局影响的倾向性匹配分析研究
Zhi-Xin Wang,Le-Le Chang,Jing Liu et al.
Zhi-Xin Wang et al.
Background: The management of stage IB-IIB cervical cancer (CC) remains a matter of debate. Neoadjuvant therapy (NAT) followed by surgery has emerged as a potential alternative to upfront radical surgery. This study aimed...
Corylin inhibits liver cancer cell growth through the endogenous apoptosis and mitophagy [0.03%]
金莲花内酯通过诱导肝癌细胞线粒体自噬和凋亡抑制肿瘤生长
Renshuang Zhao,Xin Wang,Mingming Cao et al.
Renshuang Zhao et al.
Background: Corylin is a bioactive extract of Psoralea corylifolia L. with reported antioxidant, anti-tumor, and anti-inflammatory effects. Its anti-tumor effects have been investigated, but mechanistic explanations are l...
A pretreatment 18F-FDG PET/CT-based nomogram for the differential diagnosis of primary gastric cancer and primary gastric diffuse large B-cell lymphoma [0.03%]
基于前期治疗18F-FDG PET/CT的直肠癌和直肠弥漫大B细胞淋巴瘤鉴别诊断列线图
Ran Wang,Wei Wang,Xun Shi et al.
Ran Wang et al.
Background: It is challenging to differentiate between primary gastric cancer (GC) and primary gastric diffuse large B-cell lymphoma (PG-DLBCL) with traditional imaging modalities. This study aimed to develop a predictive...
Survival outcomes by molecular subtypes based on receptor status in medullary breast carcinoma: a SEER database analysis [0.03%]
基于受体状态的分子亚型的生存结果：来自SEER数据库分析的乳腺髓样癌
Manxiu Li,Hong Tao,Shun Wu et al.
Manxiu Li et al.
Background: Medullary breast carcinoma (MBC) is a rare histological subtype of invasive breast cancer. This study aimed to compare prognostic outcomes between MBC and invasive breast carcinoma of no special type (IBC-NST;...
Andres A Caro,Francesca V LoBianco,Nukhet Aykin-Burns
Andres A Caro