Expression profiling, molecular subtyping and prognostic signature construction of chemokines and chemokine receptors in gastric cancer [0.03%]
胃癌中细胞因子诱导的共刺激因子表达谱分析、分子分型及预后特征构建
Tianshu Feng,Yaoqi Li,Jieyu Hu et al.
Tianshu Feng et al.
Background: Gastric cancer (GC) is a highly heterogeneous malignancy of the digestive tract, with significant variations in treatment response and clinical prognosis depending on its molecular subtypes. Chemokines and che...
Phase separation of MARCH1 promotes rectal adenocarcinoma progression through PHLPP2 ubiquitination [0.03%]
MARCH1相分离通过PHLPP2泛素化促进直肠腺癌进展
Luyao Ma,Wengang Qiu,Jie Jiang et al.
Luyao Ma et al.
Background: Membrane-associated RING-CH 1 (MARCH1) is an E3 ubiquitin ligase that functions as an oncogene in colorectal cancer, but its role in rectal adenocarcinoma (READ) remains unclear. This study aimed to explore th...
Risk factors for short-term survival in EGFR-mutated non-small cell lung cancer with brain metastasis and prognosis of the leptomeningeal metastasis subgroup: a retrospective cohort study [0.03%]
EGFR突变型非小细胞肺癌脑转移患者短期生存影响因素及脑膜转移亚组预后分析：一项回顾性队列研究
Jinghaozheng Bo,Zhuoxuan Wu,Yanyan Yang et al.
Jinghaozheng Bo et al.
Background: Prognostic stratification for epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) patients with brain metastases (BM) varies widely, and identifying drivers of early mortality re...
Integrative bioinformatics and experimental analysis identify S100A10 as a diagnostic and prognostic biomarker in pancreatic adenocarcinoma [0.03%]
整合生物信息学和实验分析鉴定S100A10作为胰腺导管腺癌的诊断和预后生物标志物
Pengzhao Song,Tianqi Chen,Qingqun Guo et al.
Pengzhao Song et al.
Background: Pancreatic adenocarcinoma (PAAD) is an extremely invasive malignancy with limited effective treatment options. S100 calcium-binding protein A10 (S100A10), a protein-coding gene, plays a critical role in tumor ...
Angiotensin system inhibitors as adjunctive therapy in esophageal adenocarcinoma: hypothesis-generating insights from incidental use during trimodal treatment [0.03%]
血管紧张素系统抑制剂作为反流性食管腺癌联合治疗的辅助疗法：三联治疗期间偶然使用时对疗效的假设生成式研究观点
Alberto Carmona-Bayonas,Paula Jimenez-Fonseca
Alberto Carmona-Bayonas
Comprehensive bioinformatics analysis identifies DNA methylation signatures associated with immune evasion and predicts immunotherapy response in breast cancer [0.03%]
全面生物信息学分析鉴定出与乳腺癌免疫逃逸相关的DNA甲基化标志物并预测免疫治疗反应
Yurong Cheng,Jing Wang,Dong Yan
Yurong Cheng
Background: Breast cancer exhibits substantial immunological heterogeneity, and immune evasion is a key mechanism driving tumor progression and therapeutic resistance. However, robust epigenetic biomarkers reflecting immu...
Effects of different drugs on radiation-induced oral mucositis in patients with head and neck tumors: a systematic review and a network meta-analysis [0.03%]
不同药物对头颈部肿瘤放疗相关放射性口腔黏膜炎疗效的系统评价和网络meta分析
Shuchang Lou,Xiaodong Li,Lingyun Shi
Shuchang Lou
Background: Radiation-induced oral mucositis (RIOM) affects over 80% of head and neck tumor patients receiving radiotherapy. Although four routine drugs are used for RIOM prevention, direct comparative evidence across mul...
Potential role of PPARGC1A in linking ulcerative colitis to colorectal cancer: a novel prognostic biomarker and therapeutic target [0.03%]
PPARGC1A在溃疡性结肠炎致癌过程中的潜在作用：一种新型的预后标志物和治疗靶点
Bo Fan,Wenzheng Li,Zhiyuan Wei
Bo Fan
Background: The rising incidence of ulcerative colitis (UC) worldwide significantly increases the risk of ulcerative colitis-associated colorectal cancer (UC-CRC). Although chronic inflammation drives the inflammation-dys...
The evolving landscape of early diagnosis for hepatocellular carcinoma: a bibliometric analysis of global research trends (2016-2026) based on WoSCC database [0.03%]
基于WoSCC数据库（2016-2026）的全球研究趋势：肝细胞癌早期诊断演变格局的计量学分析
Lihua Chen,Zhekun Huang,Songbin Lin et al.
Lihua Chen et al.
Background: Posing a severe global health challenge, hepatocellular carcinoma (HCC) has persistently poor prognosis, that is mainly attributed to its advanced stage at diagnosis. The explosion of information makes it diff...
Association between the Prognostic Nutritional Index and survival outcomes in hepatocellular carcinoma patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis [0.03%]
预后营养指数与肝细胞癌免疫检查点抑制剂治疗患者生存结局之间的相关性：系统评价和Meta分析
Jiajia Qian,Shang Gao,Yunhao Zhu et al.
Jiajia Qian et al.
Background: Immune checkpoint inhibitors (ICIs) have improved outcomes in advanced hepatocellular carcinoma (HCC), but substantial heterogeneity in treatment response and survival remains. The Prognostic Nutritional Index...