Identification and validation of a sphingolipid metabolism-related prognostic signature for predicting prognosis and immune microenvironment-related characteristics in ovarian cancer [0.03%]
识别并验证卵巣癌预后及相关免疫微环境特征的鞘脂代谢相关标志物
Xin Lian,Hao Chang,Yun Yang et al.
Xin Lian et al.
Background: Ovarian cancer (OV) is the leading cause of mortality among gynecological malignancies, often diagnosed at an advanced stage and prone to recurrence after treatment. In order to improve the prognosis, there is...
Gene expression profile, and role of baicalein in the inhibition of thyroid cancer [0.03%]
基因表达谱及Baicalin抑制甲状腺癌的作用
Nan Wu,Qian Zhang,Muhammad Naeem et al.
Nan Wu et al.
Background: Anaplastic thyroid cancer (ATC) is the highly undifferentiated form of thyroid cancer, and its incidence is still high all around the globe. The current treatment for ATC includes surgery, chemotherapy, and ra...
MicroRNA-663a upregulation upon ARID1A depletion promotes the growth and migration of esophageal cancer cells by targeting FKBP8 [0.03%]
ARID1A缺失通过靶向FKBP8促进microRNA-663a上调食管癌细胞的生长和迁移
Hongli Liao,Chunyi Ren,Yi Jiang et al.
Hongli Liao et al.
Background: ARID1A loss has been shown to promote the development and progression of cancers by modulating different target genes, including microRNAs (miRs). This study was performed to identify ARID1A-regulated miRs inv...
Beyond the lung: recognizing incidental breast lesions on chest computed tomography [0.03%]
超越肺部认识胸部CT上的乳腺意外病变
Bo Mi Gil,Yoon Ki Cha,Hyungin Park et al.
Bo Mi Gil et al.
With the widespread use of chest computed tomography (CT) for thoracic evaluation, incidental breast findings are increasingly encountered in routine clinical practice. Although most of these findings are benign, breast cancer may occasiona...
KRT80 promotes colon adenocarcinoma progression via stat3 pathway activation and immune microenvironment remodeling [0.03%]
KRT80通过STAT3途径活化和免疫微环境重塑促进结肠腺癌进展
Lu Nie,Yu Nie,Ruiyang Wang
Lu Nie
Background: Colorectal adenocarcinoma (COAD) is a leading cause of cancer-related death globally, necessitating the identification of new molecular drivers and therapeutic targets. Keratin 80 (KRT80) is an intermediate fi...
Targeting chitinase-3-like protein 2 (CHI3L2) suppresses cell proliferation and migration in glioblastoma [0.03%]
靶向半乳糖凝集素3抑制胶质母细胞瘤的细胞增殖和迁移
Zhihong Liu,Dihui Chen,Sijia Liao et al.
Zhihong Liu et al.
Background: Glioblastoma (GBM), the most common and aggressive subtype of glioma, currently lacks effective therapeutic targets. This study aimed to elucidate the role of chitinase-3-like protein 2 (CHI3L2) and its underl...
Low LAMA2 expression may affect drug resistance and prognosis in ovarian cancer via positive LGR5 coexpression [0.03%]
LAMA2低表达通过正向调控LGR5影响卵巢癌的耐药及预后
Zhe Du,Yuting Su,Lianping Xia et al.
Zhe Du et al.
Background: Drug resistance often occurs during ovarian cancer (OC) treatment, and factors related to drug resistance often contribute to poor prognosis. Laminin subunit alpha 2 (LAMA2) can affect cancer progression, but ...
Systematic evaluation and meta-analysis of the diagnostic accuracy of ultrasound contrast in predicting the efficacy of systemic therapy for advanced hepatocellular carcinoma [0.03%]
系统评价和荟萃分析超声造影预测肝细胞癌全身治疗疗效的诊断准确性
Mingsheng Zhu,Hang Li,Xiaolu Liang et al.
Mingsheng Zhu et al.
Background: Contrast-enhanced ultrasound (CEUS) is a dynamic, noninvasive imaging modality capable of real-time visualization of tumor perfusion characteristics. This systematic review and meta-analysis quantitatively eva...
Development and feasibility assessment of an automated, synthetic CT-guided plan selection system for bladder cancer adaptive radiotherapy: a retrospective pilot study [0.03%]
一种自动化、合成CT引导的计划选择系统在膀胱癌适应性放射治疗中的研发和可行性评估：一项回顾性试点研究
Huipeng Meng,Xinrui Wang,Pengfei Liu et al.
Huipeng Meng et al.
Background: Interfractional bladder volume variation during radiotherapy challenges the optimality of a single treatment plan. We developed and conducted a pilot feasibility study of a decision support system to select th...
SERPINH1, a regulatory factor of oligodendroglioma cell invasion and extracellular matrix secretion, as a novel prognostic biomarker and therapeutic target [0.03%]
SERPINH1作为少突胶质细胞瘤侵袭和基底膜分泌的调节因子，是一种新的预后标志物和治疗靶点
Xue Chen,Shunyao Li,Huijuan Zhao et al.
Xue Chen et al.
Background: Oligodendroglioma is a specific type of brain glioma, and relatively little research has been conducted on it. The expression and prognosis of serine protease peptidase inhibitor, branch H, member 1 (SERPINH1)...