The impact of neoadjuvant chemoimmunotherapy on pulmonary function in non-small cell lung cancer patients [0.03%]
新辅助化疗免疫治疗对非小细胞肺癌患者肺功能的影响
Ao Zeng,Zhilong Xu,Abudumijiti Abuduwayiti et al.
Ao Zeng et al.
Background: Perioperative chemoimmunotherapy has suggested a survival benefit in patients with locally-advanced non-small cell lung cancer (NSCLC). This study aims to investigate whether neoadjuvant chemoimmunotherapy inf...
Pathological and molecular characterization of a four-component combined small cell lung carcinoma: a case report [0.03%]
小细胞肺癌四种组织成分共存的病理及分子特征分析——一例报告
Yasuyuki Ikezawa,Yoshiki Shinomiya,Kanako C Hatanaka et al.
Yasuyuki Ikezawa et al.
Background: Combined small cell lung carcinoma (SCLC) is a rare entity and characterized by the coexistence of SCLC and non-small cell lung cancer (NSCLC) components. We report the first known case of combined SCLC contai...
Exploring the effectiveness and sequence of brain local treatment combined with thoracic surgery in non-small cell lung cancer patients with brain oligometastasis [0.03%]
探究非小细胞肺癌脑寡转移患者脑局部治疗联合胸手术的有效性及顺序
Ruihe Liu,Jiayuan Tian,Shenhua Liang et al.
Ruihe Liu et al.
Background: Non-small cell lung cancer (NSCLC) with brain metastases represents approximately 10% of new cancer cases globally. Brain local treatments in addition to resection of the primary lung tumor has been shown to b...
Targeting heterogeneity in atypical epidermal growth factor receptor-mutated non-small cell lung cancer: insights from CHRYSALIS-2 [0.03%]
针对非典型表皮生长因子受体突变型非小细胞肺癌的异质性进行靶向治疗：CHRYSALIS-2研究的新见解
Yosuke Dotsu,Hiroshi Mukae
Yosuke Dotsu
Xinqing Lin,Qian Chu,Yuchao Dong et al.
Xinqing Lin et al.
Background: Following the 2021 first International Consensus on Severe Lung Cancer, global attention to patients with PS 2-4 has grown significantly. Recent advances in novel therapies, interventional techniques, and supp...
Pulmonary ground glass opacity tumor: a curable subtype of lung cancer when treated within the "surgical curative time window" [0.03%]
肺磨玻璃结节瘤在“外科治愈时间窗”内治疗可达到根治效果
Ting Ye,Haoxuan Wu,Haiquan Chen
Ting Ye
With the application of low-dose computed tomography (CT) screening for lung cancer in wider range of populations in Asia, a high prevalence of pulmonary ground glass opacity (GGO) tumors has been found in younger females or non-smokers. Th...
A lung squamous cell carcinoma demonstrating spontaneous partial regression of the primary tumor with lymph node metastasis: a case report with analysis of the tumor immune microenvironment [0.03%]
一例原发肿瘤自发部分消退但发生淋巴结转移的肺鳞癌病例报告及肿瘤免疫微环境分析
Hiroyuki Yamada,Yoshihiro Komohara,Takamasa Koga et al.
Hiroyuki Yamada et al.
Background: Spontaneous regression (SR) of malignant tumors is a well-known but rare phenomenon in lung cancer. Previous studies have suggested that antitumor immune responses may contribute to SR. ...
Preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT)-based strategy for predicting negative mediastinal lymph node metastasis status in non-small cell lung cancer [0.03%]
基于术前18F-脱氧葡萄糖正电子发射断层扫描/X线计算机体层成像（18F-FDG PET/CT）的策略用于预测非小细胞肺癌患者的阴性纵隔淋巴结转移状态
Juntian Yao,Fangqiu Fu,Nan Li et al.
Juntian Yao et al.
Background: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is standard for detecting mediastinal lymph node (MLN) metastasis staging in non-small cell lung cancer (NSCLC). However...
Two-year treatment-free sustained remission after chemo-immunotherapy in a 52-year-old male with recurrent ARID1A-mutant lung adenocarcinoma: a case report [0.03%]
携带ARID1A突变的复发性肺腺癌男性患者经化疗免疫治疗后实现两年无病生存：一例个案报告
Pedro Gonzalez Santa-Catalina,Daniel Morchón-Araujo,Marta Rodríguez-González et al.
Pedro Gonzalez Santa-Catalina et al.
Background: Immune checkpoint inhibitors (ICIs) have reshaped the management of advanced non-small cell lung cancer (NSCLC), yet only a subset of patients derive durable benefit and reliable predictive biomarkers remain l...
Understanding the dual role of granulocyte-macrophage colony-stimulating factor in the lung cancer tumor microenvironment and its therapeutic implications [0.03%]
粒细胞-巨噬细胞集落刺激因子在肺癌肿瘤微环境中的双重作用及其治疗意义的理解
Gang Wei,Xuanji Zhu,Rui Zhong
Gang Wei
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pleiotropic cytokine that plays a complex and critical dual regulatory role in the development, progression, and immunotherapy of lung cancer. In recent years, with the deepenin...