DNA damage and repair (DDR) gene mutation profiles in driver gene wild-type advanced non-small cell lung cancer and the predictive role of response to platinum-based chemotherapy [0.03%]
驱动基因为野生型的晚期非小细胞肺癌患者中DNA损伤及修复（DDR）基因突变特征及其预测铂类化疗疗效的作用
Tianxiu Wu,Yu Xu,Qiuyue Song et al.
Tianxiu Wu et al.
Background: Platinum-based chemotherapy is an important therapeutic approach for patients with advanced non-small cell lung cancer (NSCLC) without driver gene mutations. DNA damage and repair (DDR) gene can mitigate plati...
Impact of immune-related adverse events on clinical outcomes in patients with advanced non-small cell lung cancer with low PD-L1 expression, focusing on pneumonitis: a multicenter retrospective study in Japan [0.03%]
免疫相关不良事件对低PD-L1表达晚期非小细胞肺癌患者临床结局的影响：以肺炎为例的日本多中心回顾性研究
Shiho Goda,Tadaaki Yamada,Kenji Morimoto et al.
Shiho Goda et al.
Background: Severe immune-related adverse events (irAEs) are often associated with combined immunotherapy and chemotherapy in patients with non-small cell lung cancer (NSCLC). However, their effect on clinical outcomes ha...
Comparing neutrophil-to-lymphocyte ratio (NLR), absolute neutrophil count (ANC) and derived NLR as predictive biomarkers in first-line immunotherapy for non-small cell lung cancer: a retrospective study [0.03%]
中性粒细胞与淋巴细胞比例(NLR)、绝对中性粒细胞计数(ANC)和衍生NLR在非小细胞肺癌一线免疫治疗中的预测价值：一项回顾性研究
Elise Longueville,Maxime Dewolf,Véronique Dalstein et al.
Elise Longueville et al.
Background: Lung cancer, especially non-small cell lung cancer (NSCLC), poses a significant global health challenge due to its high prevalence and poor prognosis despite treatment advancements, including immunotherapy. Wh...
Diagnostic accuracy of serum biomarkers MMP11 and SPP1 in non-small cell lung cancer: an analysis of sensitivity, specificity, and area under the curve [0.03%]
用于非小细胞肺癌诊断的血清标志物MMP11和SPP1的准确性：敏感性、特异性和曲线下面积分析
Minha Lea Yoon,Sang Yean Kim,Hyelim Chun et al.
Minha Lea Yoon et al.
Background: Non-small cell lung cancer (NSCLC) represents the vast majority of lung cancer cases, comprising 80-85% of all diagnoses, and continues to be a primary contributor to cancer-related deaths. Early detection is ...
FOXO3a regulation of non-small cell lung cancer radiotherapy resistance through the PINK1/Parkin pathway of protective mitophagy [0.03%]
FOXO3a通过PINK1/Parkin途径调节保护性线粒体自噬从而调控非小细胞肺癌放射抵抗性
Xiaoting Wu,Litang Huang,Lu Meng et al.
Xiaoting Wu et al.
Background: Radiotherapy resistance has become one of the major causes of radiotherapy failure among patients with non-small cell lung cancer (NSCLC), but its underlying mechanism remains unclear. In recent years, the inf...
Clinical implication of tumor spread through air spaces in stage IA lung adenocarcinoma: prognostic impact and association with the International Association for the Study of Lung Cancer (IASLC) grade [0.03%]
肿瘤通过空气间隙扩散在IA期肺腺癌中的临床意义：预后影响及与国际肺癌研究协会（IASLC）级别的关联
Jinghan Shi,Kuan Xu,Xufeng Liu et al.
Jinghan Shi et al.
Background: Tumor spread through air spaces (STAS) and a new histological grading system proposed by the International Association for the Study of Lung Cancer (IASLC) have been studied for risk stratification and prognos...
Multidisciplinary international expert consensus on perioperative airway management [0.03%]
多学科国际专家共识：围术期气道管理
Hengrui Liang,Guowei Che,Fei Cui et al.
Hengrui Liang et al.
Background: Perioperative airway management is critical for patient safety and optimal surgical outcomes. Effective airway management reduces postoperative pulmonary complications and accelerates recovery. This expert con...
Prevalence of EGFR gene mutations in patients with early-stage resectable non-small cell lung cancer in Spain: the ORIGEN study [0.03%]
西班牙早中期可手术非小细胞肺癌患者EGFR基因突变流行病学研究（ORIGEN研究）
Mar Varela,Cristina Teixidó,Carlos Álvarez-Fernández et al.
Mar Varela et al.
Background: Geographic variability in epidermal growth factor receptor (EGFR) mutation rates in early-stage non-small cell lung cancer (NSCLC) has been reported. However, the frequency of EGFR mutations in patients with e...
Uniportal video-assisted thoracoscopic surgery does not increase recurrence rates following pneumonectomy in non-small cell lung cancer: a retrospective study from the National Cancer Center of China [0.03%]
单孔视频辅助胸腔镜手术不会增加我国肺癌患者全肺切除术后的复发率：一项回顾性研究
Sikai Wu,Xiaowei Chen,Guangyu Bai et al.
Sikai Wu et al.
Background: The safety, feasibility, and potential benefits of uniportal video-assisted thoracoscopic surgery (U-VATS) pneumonectomy remain to be investigated. This study aimed to evaluate the postoperative outcomes, surv...
Metabolic tumor volume on 18F-FDG uptake as a negative predictor after ipilimumab plus nivolumab in advanced non-small cell lung cancer [0.03%]
甲磺酸伊马替尼联合培美曲塞和卡铂治疗晚期非鳞非小细胞肺癌患者血清miRNA-21及临床疗效的初步研究
Kosuke Hashimoto,Kyoichi Kaira,Atsuto Mouri et al.
Kosuke Hashimoto et al.
Background: Nivolumab plus ipilimumab (Nivo-Ipi) is a standard treatments for metastatic or recurrent non-small cell lung cancer (NSCLC). Unlike programmed death-1 (PD-1) inhibitor monotherapy, the possible predictors of ...