Yusuf Bugra Severoglu,Betul Yuksel,Cagatay Sucu et al.
Yusuf Bugra Severoglu et al.
Solvents represent the quiet majority in biomolecular systems, yet modeling their influence with both speed and ri:gor remains a central challenge. This study maps the state of the art in implicit solvent theory and practice, spanning class...
Isolation and Identification of Duck Intestinal Probiotics and Their Effects on the Production and Immune Performance of Pekin Ducks [0.03%]
鸭肠道益生菌的分离鉴定及其对樱桃谷鸭生产性能和免疫性能的影响
Zhigang Hu,Zhuo Zhi,Huiya Zhang et al.
Zhigang Hu et al.
The purpose of this study was to investigate the effects of duck-derived probiotics added to drinking water on the production and immune performance of Pekin ducks. Two strains with good biological characteristics were isolated from the cec...
Improvement of Soluble Expression, Stability, and Activity of Acetaldehyde Lyase by Elastin-like Polypeptides Fusion for Acetoin Production from Acetaldehyde [0.03%]
融合弹性蛋白多肽改善乙醛裂解酶可溶性表达、稳定性和活性提高丙酮酸生物合成效能
Hui Lin,Jiming Zhang,Jie Hu et al.
Hui Lin et al.
To achieve the large-scale, low-cost preparation of acetaldehyde lyase (ALS), elastin-like polypeptides (ELPs) as non-chromatographic purification tags were employed to develop an ELP-ALS fusion protein in Escherichia coli. Induction expres...
The Role of Preconception Parental Health on Embryo Quality-Preliminary Results of a Prospective Study Using Non-Invasive Preimplantation Genetic Testing for Aneuploidy [0.03%]
关于妊娠前父母健康状况对胚胎质量的影响——采用非侵入性胚胎植入前染色体异常筛查的前瞻性研究初步结果
Maja Tomic,Eda Bokal-Vrtacnik,Martin Stimpfel
Maja Tomic
In this study, we aimed to correlate embryonic ploidy status studied with non-invasive preimplantation genetic testing for aneuploidy with the basic patient characteristics of the infertile couple to gain insight into the effects of parenta...
Supercomplex Restructuring in Heart Mitochondria of COX7A1-Deficient Mice [0.03%]
COX7A1缺陷小鼠心脏线粒体超复合物重排
Lauren Pavelich,Lucynda Pham,Paul Stemmer et al.
Lauren Pavelich et al.
The role of electron transport chain supercomplexes and factors that regulate their composition in a tissue- and species-specific manner are not fully understood. Tissue-specific isoforms have been reported for cytochrome c oxidase (COX), w...
Exploring the Allosteric Pathways of Asciminib in the Dual Inhibition of BCR-ABL1 [0.03%]
探索单环阿雷利克素辛布对BCR-ABL1的别构通路及其双重抑制作用
Jie Ming,Hongwei Gao,Jiuyu Zhan
Jie Ming
The BCR-ABL1 fusion protein is a critical therapeutic target in Chronic Myeloid Leukemia (CML). Current monotherapy approaches involve types of inhibitors that can be categorized into ATP competitive inhibitors and allosteric inhibitors. Ho...
An In Vitro Study of Protein S-Glutathionylation by Members of the CLIC Protein Family [0.03%]
CLIC蛋白家族成员体外研究蛋白质S-谷硫基化作用
Wendy El Khoury,Khondker Rufaka Hossain,Amani Alghalayini et al.
Wendy El Khoury et al.
Increasing evidence points to members of the chloride intracellular ion channel (CLIC) protein family performing a variety of functions within cells-classifying them as moonlighting proteins-and serving as natural cellular antioxidant prote...
Chinese Medicine-Derived Natural Compounds and Intestinal Regeneration: Mechanisms and Experimental Evidence [0.03%]
源自中药的天然化合物与肠道再生：机制及实验证据
Fengbiao Guo,Shaoyi Zhang
Fengbiao Guo
Intestinal regeneration is essential for maintaining epithelial integrity and repairing mucosal damage caused by inflammation, infections, or injuries. Traditional Chinese Medicine (TCM) has long utilized herbal remedies for gastrointestina...
Oleuropein Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice by Targeting TGF-β1 Signaling Pathway [0.03%]
橄榄苦素通过靶向TGF-β1信号途径改善博来霉素致小鼠肺纤维化
Liang Zhang,Zhigang Liu,Yayue Hu et al.
Liang Zhang et al.
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by the accumulation of fibrotic tissue in the lungs, leading to impaired gas exchange and respiratory failure, with a poor prognosis and l...
Carboxy-Methylation of the Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Integrates Methionine Availability with Methionine Addicted Cancer Cell Proliferation [0.03%]
脯氨酶2A催化亚基的羧甲基化将甲硫氨酸的可获得性与依赖于甲硫氨酸的癌细胞增殖相整合
Anna Andronicos,Kiku C Yoneda,Da-Wei Lin et al.
Anna Andronicos et al.
Cancer cells exhibit a well-documented, yet poorly understood, dependence on exogenous methionine, despite retaining the capacity to convert homocysteine to methionine. In contrast, non-tumorigenic cells can proliferate when methionine is r...