A Multi-Ingredient Supplement Improves Body Re-Composition, Ovarian Aging Markers, and Reproductive Success in Young and Middle-Aged Female Mice [0.03%]
一种多成分补充剂可改善年轻和中年雌性小鼠的身体组成、卵巢衰老标志物和生殖成功率
Alessandra Chiarot,Mahek Minhas,Nicoletta M de Maat et al.
Alessandra Chiarot et al.
Ovarian aging is characterized by mitochondrial dysfunction, oxidative stress, and inflammation. The development of adjunctive treatments that mitigate age-related subfertility is warranted. We examined the benefits of nutraceutical supplem...
In Vitro and In Vivo Comparisons of Activated Charcoal and Biochar as Dietary Treatments for Controlling Boar Taint [0.03%]
关于控制公猪异味的饲料添加剂：体外和体内对比活性炭与生物炭的效果研究
Melissa Parent,Christine Bone,Lee-Anne Huber et al.
Melissa Parent et al.
Activated charcoal (AC) is an adsorbent that can prevent the accumulation of boar taint-causing compounds in the fat, but is not an approved dietary additive for livestock animals. Biochar (BC) is a similar feed-approved charcoal adsorbent ...
Comparative Study
Biomolecules. 2025 Aug 30;15(9):1257. DOI:10.3390/biom15091257 2025
Neuromuscular Defects in a Drosophila Model of the Congenital Disorder of Glycosylation SLC35A2-CDG [0.03%]
SLC35A2-CDG糖基化障碍果蝇模型中的神经肌肉缺陷
Kazuyoshi Itoh,Masaki Kurogochi,Tadashi Kaname et al.
Kazuyoshi Itoh et al.
SLC35A2-CDG is a congenital disorder of glycosylation caused by mutations in the SLC35A2 gene encoding a Golgi-localized UDP-galactose transporter. This transporter plays an essential role in glycan synthesis by transporting UDP-galactose f...
Structural and Functional Studies on Key Epigenetic Regulators in Asthma [0.03%]
哮喘相关表观遗传调控蛋白的结构与功能研究
Muhammad Fakhar,Mehreen Gul,Wenjin Li
Muhammad Fakhar
Asthma is a chronic inflammatory airway disease influenced by both genetic and environmental factors. Recent insights have underscored the pivotal role of epigenetic regulation in the pathogenesis and heterogeneity of asthma. This review fo...
Biomarker Signatures in Time-Course Progression of Neuropathic Pain at Spinal Cord Level Based on Bioinformatics and Machine Learning Analysis [0.03%]
基于生物信息学和机器学习分析的神经病理性疼痛脊髓水平时间进程标志物签名研究
Kexin Li,Ruoxi Wang,He Zhu et al.
Kexin Li et al.
Neuropathic pain (NP) is a debilitating chronic pain condition with complex molecular mechanisms and inadequate therapeutic solutions. This study aims to identify temporal transcriptomic changes in NP using multiple bioinformatics and machi...
Antibiofilm Inhibitor Ferulic Acid as an Antibacterial Synergist Against Escherichia coli [0.03%]
对乙酸苯酚作为抑菌协同剂对抗大肠杆菌菌膜的作用
Zhijin Zhang,Jing Xu,Xiaojuan Wei et al.
Zhijin Zhang et al.
Escherichia coli (E. coli) is a severe foodborne pathogen, and the formation of its biofilm can enhance bacterial virulence and reduce antibiotic sensitivity, posing a significant threat to human and animal health. Ferulic Acid (FA) is a na...
Mitochondrial Aging in the CNS: Unravelling Implications for Neurological Health and Disease [0.03%]
中枢神经系统中的线粒体衰老：探讨其对神经健康和疾病的影响
Davide Steffan,Camilla Pezzini,Martina Esposito et al.
Davide Steffan et al.
Mitochondrial aging plays a central role in the functional decline of the central nervous system (CNS), with profound consequences for neurological health. As the brain is one of the most energy-demanding organs, neurons are particularly su...
Construction of Yeast One-Hybrid Library of Dendrobium huoshanense and Screening of Potential Transcription Factors Regulating DhPMM Gene Expression [0.03%]
石斛中华矮生种酵母单杂交文库的构建及DhPMM基因调控转录因子的筛选
Jing Wu,Shuting Wang,Shihai Xing et al.
Jing Wu et al.
Dendrobium huoshanense, an endangered orchid species, is renowned for its polysaccharides with vast pharmacological significance in stems. Phosphomannomutase (PMM) critically regulates polysaccharide accumulation. Transcriptional regulation...
Ashes to Rashes: An Exploration of the Intersection Between Smoking and Cutaneous Lupus Erythematosus [0.03%]
灰烬与皮疹：吸烟和盘状红斑狼疮关系的探究
Rafael O Homer,Ahmed Eldaboush,Darae Kang et al.
Rafael O Homer et al.
Cutaneous lupus erythematosus is an autoimmune skin disorder with a known association with cigarette smoking. Smokers with cutaneous lupus have a worse disease course and may be refractory to treatments. Despite many studies documenting thi...
Glycerol Kinase 2 as a Metabolic Sentinel for Human Sperm Motility and Male Fertility [0.03%]
甘油激酶2作为人类精子运动和男性生育力的代谢哨兵
João S Oliveira,Rúben J Moreira,Ana D Martins et al.
João S Oliveira et al.
Male infertility affects 8-12% of couples worldwide and is solely responsible in up to 30% of cases. Assisted Reproductive Technologies (ARTs) provide potential solutions, particularly in conditions where spermatozoa display structural abno...