Anticancer Activity Evaluation of New Thieno[2,3- d]pyrimidin-4(3 H)-ones and Thieno[3,2- d]pyrimidin-4(3 H)-one Derivatives [0.03%]
新型噻诺并.pyrimidin-4 ones和噻诺并.pyrimidin-4 ones衍生物抗肿瘤活性评价
Olga Shyyka,Nazariy Pokhodylo,Nataliya Finiuk et al.
Olga Shyyka et al.
Anticancer screening of several novel thienopyrimidines has been performed. The thienopyrimidine derivatives were synthesized from available starting materials according to the convenient synthetic procedures using a one-pot solvent-free re...
Antidepressant-Like Effect of Lippia sidoides CHAM (Verbenaceae) Essential Oil and Its Major Compound Thymol in Mice [0.03%]
香蜂草属 Cham 素油及其主要化合物丁子香酚的抗抑郁作用研究
Michele Sanford Rangel Parente,Feliphy Rodrigues Custódio,Nayara Araújo Cardoso et al.
Michele Sanford Rangel Parente et al.
Depression is a common disease affecting more than 300 million people worldwide. Since Lippia sidoides has shown central nervous system effects in previous works, we aimed to investigate the effect of L. sidoides essential oil and its major...
Thiopyrano[2,3- d]Thiazoles as New Efficient Scaffolds in Medicinal Chemistry [0.03%]
含噻唑环的噻喃并杂环类新药效骨架化合物的研究与发展
Anna Kryshchyshyn,Olexandra Roman,Andrii Lozynskyi et al.
Anna Kryshchyshyn et al.
This review presents the up to date development of fused thiopyranothiazoles that comprise one of the thiazolidine derivatives classes. Thiazolidine and thiazolidinone-related compounds belong to the widely studied heterocycles from a medic...
Synthesis and Cytotoxicity Evaluation of Novel Asymmetrical Mono-Carbonyl Analogs of Curcumin (AMACs) against Vero, HeLa, and MCF7 Cell Lines [0.03%]
新型不对称单羰基类姜黄素衍生物（AMACs）的合成及其对vero、hela和mcf7细胞系的抗肿瘤活性评价
Pekik Wiji Prasetyaningrum,Anton Bahtiar,Hayun Hayun
Pekik Wiji Prasetyaningrum
A series of novel asymmetrical mono-carbonyl analogs of curcumin (AMACs) were synthesized and evaluated for cytotoxic activity using BSLT and MTT assay against Vero, HeLa, and MCF7 cell lines. The structures of the synthesized compounds wer...
Influence of Ispaghula and Zein Coating on Ibuprofen-Loaded Alginate Beads Prepared by Vibration Technology: Physicochemical Characterization and Release Studies [0.03%]
用于制备伊布普洛芬载药海藻酸盐微球的ispaghula和zein包衣对其理化性质及体外释放行为的影响研究
Jillian Jin Lyn Heng,Jia Hao Teng,Muniyandy Saravanan et al.
Jillian Jin Lyn Heng et al.
The purpose behind the work was to fabricate alginate beads with better drug loading and extended drug release. Ispaghula was used to enhance the drug loading while zein was employed to extend the drug release. Ibuprofen was employed as a m...
Cocrystal of Ibuprofen⁻Nicotinamide: Solid-State Characterization and In Vivo Analgesic Activity Evaluation [0.03%]
布洛芬-烟酰胺共晶体的固态表征及体内镇痛活性评价
Yori Yuliandra,Erizal Zaini,Syofyan Syofyan et al.
Yori Yuliandra et al.
Ibuprofen is classified as a BCS class II drug which has low solubility and high permeability. We conducted the formation of the cocrystalline phase of ibuprofen with coformer nicotinamide to increase its solubility. The purpose of this stu...
Impact of Fermented Foods on Human Cognitive Function-A Review of Outcome of Clinical Trials [0.03%]
发酵食品对人类认知功能的影响-临床试验结果述评
Bhagavathi Sundaram Sivamaruthi,Periyanaina Kesika,Chaiyavat Chaiyasut
Bhagavathi Sundaram Sivamaruthi
Food is an essential need for all living creatures which provides the energy to maintain life and grow further. Fermentation is a process used to preserve and advance the quality of foods, and those foods are known as fermented foods. Some ...
Synthesis, Crystal Structure, and Biological Activity of Ethyl 4-Methyl-2,2-dioxo-1 H-2λ⁶,1-benzothiazine-3-carboxylate Polymorphic Forms [0.03%]
4-甲基-2,2-二氧代-1 H-2λ⁶,1-苯并噻嗪-3-羧酸乙酯多晶型物的合成、晶体结构及生物活性研究
Igor V Ukrainets,Anna A Burian,Vyacheslav N Baumer et al.
Igor V Ukrainets et al.
Continuing the search for new potential analgesics among the derivatives of 4-methyl-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxylic acid, the possibility of obtaining its esters by the alkylation of the corresponding sodium salt with iodoe...
Host-Guest Interactions of Plumbagin with β-Cyclodextrin, Dimethyl-β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin: Semi-Empirical Quantum Mechanical PM6 and PM7 Methods [0.03%]
半经验量子化学PM6和PM7方法研究天竺葵素与β-环糊精、甲基β-环糊精和羟丙基β-环糊精的主客体包合反应
Ornin Srihakulung,Ryo Maezono,Pisanu Toochinda et al.
Ornin Srihakulung et al.
Molecular interactions of plumbagin inclusion complexes with β-cyclodextrin (BCD), dimethyl--cyclodextrin (MBCD), and hydroxypropyl-β-cyclodextrin (HPBCD) were investigated by semi-empirical, Parameterization Method 6 and 7 (PM6, and PM7)...
Effect of Massoia (Massoia aromatica Becc.) Bark on the Phagocytic Activity of Wistar Rat Macrophages [0.03%]
托里朴树皮对大鼠巨噬细胞吞噬作用的影响
Triana Hertiani,Agustinus Yuswanto,Sylvia Utami Tunjung Pratiwi et al.
Triana Hertiani et al.
The essential oil of Massoia (Massoia aromatica Becc., Lauraceae) bark is a potential immunomodulator in vitro. This study evaluated the potential immunomodulatory effects of Massoia bark infusion on the nonspecific immune response (phagocy...