Radioiodination of zearalenone and determination of Lactobacillus plantarum effect of on zearalenone organ distribution: In silico study and preclinical evaluation [0.03%]
放射性碘标记玉米赤霉烯酮及植物乳杆菌对玉米赤霉烯酮组织分布影响的体外和临床前研究
M H Sanad,A B Farag,Sabry A Bassem et al.
M H Sanad et al.
Purpose: Zearalenone (ZEN) which is one of the known fusarium species mycotoxin, produced primarily on many cereal crops. Consequently, the current study aims to estimate the possibility of labeling zearalenone and the pa...
Acute exposure to environmentally relevant levels of DDT alters muscle mitochondrial function in vivo in rats but not in vitro in L6 myotubes: A pilot study [0.03%]
一项试点研究:接触环境相关浓度的DDT会改变大鼠体内肌细胞线粒体功能,但不会影响体外L6肌管的功能
Lucia Chehade,Hannah Khouri,Julie Malatier-Ségard et al.
Lucia Chehade et al.
Under insulin-stimulated conditions, skeletal muscle is the largest glucose consumer in the body. Mitochondrial dysfunction and damage to this tissue from oxidative stress are linked to the pathogenesis of type 2 diabetes. Environmental exp...
An ethnopharmacological review on the therapeutical properties of flavonoids and their mechanisms of actions: A comprehensive review based on up to date knowledge [0.03%]
基于最新知识的黄酮类化合物的治疗作用及机制的民族药理学综述
Doha H Abou Baker
Doha H Abou Baker
Flavonoids -a class of low molecular weight secondary metabolites- are ubiquitous and cornucopia throughout the plant kingdom. Structurally, the main structure consists of C6-C3-C6 rings with different substitution patterns so that many sub...
Chronic exposure to ambient traffic-related air pollution (TRAP) alters gut microbial abundance and bile acid metabolism in a transgenic rat model of Alzheimer's disease [0.03%]
长期接触与交通相关的环境空气污染(TRAP)会改变阿尔茨海默病转基因大鼠模型的肠道微生物丰度和胆汁酸代谢
Moumita Dutta,Kris M Weigel,Kelley T Patten et al.
Moumita Dutta et al.
Background: Traffic-related air pollution (TRAP) is linked to increased risk for age-related dementia, including Alzheimer's disease (AD). The gut microbiome is posited to influence AD risk, and an increase in microbial-d...
The edible plant Amaranthus hybridus (Amaranthaceae) prevents the biochemical, histopathological and fertility impairments in colibri®-treated female rats [0.03%]
食用植物苋属杂交种(amaranthaceae)可预防科尔比瑞(colibri&)处理的雌性大鼠生物化学、组织病理学和生育力损伤
Prechmy Carole Ngueyong Nsamou,Aimé Césaire Tetsatsi Momo,Yannick Baudouin Petnga Tchatat et al.
Prechmy Carole Ngueyong Nsamou et al.
Colibri® a commercial formulation of Imidacloprid severely impairs the reproductive function. This study aimed at evaluating the preventive effects of Amaranthus hybridus on the reproductive toxicity of colibri® in female rats. Eighty rat...
Comparative analysis of groundwater quality statuses and associated health risk indices of metals and total hydrocarbons at locations of tank farm in Delta State, Nigeria [0.03%]
尼日利亚三角州油罐基地地下水质量及金属和总烃健康风险指数的比较分析
Enuneku Alex Ajeh,Odeniyi Olalere Kayode,Isibor Patrick Omoregie
Enuneku Alex Ajeh
The study aimed at assessing the groundwater quality and the associated health implications of oil storage tank farms in Asaba, Oghara, Warri, and Koko towns, in Delta State, Nigeria. Fe, Cr, Cd, Ni, Pb, and V concentrations in the groundwa...
Cytotoxic and other bioactivities of a novel and known sesquiterpene lactones isolated from Vernonia leopoldi (Sch. Bip. ex Walp.) Vatke in breast cancer cell lines [0.03%]
从Vernonia leopoldi中分离得到的新型和已知倍半萜内酯的细胞毒和其他生物活性成分:乳腺癌细胞系中的作用研究
Nigatu Tuasha,Zilma Escobar,Daniel Seifu et al.
Nigatu Tuasha et al.
Vernonia leopoldi (Sch. Bip. ex Walp.) Vatke (Asteraceae) is one of the widely used anti-cancer traditional medicinal plants in Ethiopia, despite the lack of data to support its therapeutic efficacy. Here we describe the isolation of compou...
Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice [0.03%]
发育期砷暴露小鼠认知改变相关的组蛋白甲基化谱系全基因组重编程规律研究
Nicholas F Fitz,Aaron Barchowsky,Radosveta Koldamova et al.
Nicholas F Fitz et al.
Inorganic arsenic is a xenobiotic entering the body primarily through contaminated drinking water and food. There are defined mechanisms that describe arsenic's association with increased cancer incidence, however mechanisms explaining arse...
Toxicological evaluation of the red mold rice extract, ANKASCIN 568-R: 13-week chronic toxicity, and genotoxicity studies [0.03%]
红曲霉菌提取物ANKASCIN 568-R的毒理学评估:慢性毒性及遗传毒性研究
Che-Wei Lin,Hsiao-Lin Chen,Yu-Hui Yang et al.
Che-Wei Lin et al.
ANKASCIN 568-R is an extract derived from red mold rice (RMR) fermented using Monascus purpureus NTU 568. RMR fermented using M. purpureus NTU 568 prevents cardiovascular diseases and decreases blood lipid levels. This study evaluates the s...
Exposure of pigs to glyphosate affects gene-specific DNA methylation and gene expression [0.03%]
猪暴露于草甘膦会影响基因特异性DNA甲基化和基因表达
Knud Larsen,Thomas Bové Christensen,Ole Højberg et al.
Knud Larsen et al.
Glyphosate (N-(phosphonomethyl)glycine) is a broad-spectrum systemic herbicide and crop desiccant. Glyphosate has long been suspected of leading to the development of cancer and of compromising fertility. Herbicides have been increasingly r...