Heated tobacco product aerosol emission compared to cigarette smoke: A scoping review [0.03%]
加热烟草产品气溶胶排放与卷烟烟雾对比：系统评价研究
Stefano Bellosta,Alberto Corsini,Gabriele Catena
Stefano Bellosta
Heated tobacco products (HTPs) are promoted as reduced-risk alternatives to combustible tobacco cigarettes (TCs), yet toxicant exposure reduction and associated health benefits remain uncertain. We evaluated preclinical and interventional c...
Polycyclic aromatic hydrocarbon exposure in battlefield and beyond: Implications for environmental- and human health [0.03%]
战场及战场外的多环芳烃暴露：环境和人类健康的影响
Markis&#x; D Hamilton,Ritu Chauhan,Anthony E Archibong et al.
Markis&#x; D Hamilton et al.
Polycyclic aromatic hydrocarbons (PAHs) are combustion pollutants that are released into the environment through natural events and anthropogenic activities. Exposures to PAHs occur in military personnel during garrison (non-combat) and act...
Acute and subacute oral toxicity assessment of Karanjin in Sprague Dawley rats [0.03%]
Karanjin对Sprague Dawley大鼠的急性与亚急性口服毒性评估
Natasha Sura Anak Lubau,Vinod Balasubramaniam,Christina Gertrude Yap et al.
Natasha Sura Anak Lubau et al.
Karanjin (KRN) is a benzofuran flavonoid derived from Pongamia pinnata seeds, known for its antihyperglycemic and anti-inflammatory properties. Despite its traditional use, comprehensive toxicological data are limited. This study evaluated ...
Genotoxicity risk assessment of a 7-hydroxymitragynine-enriched Kratom preparation: An integrated in silico and in vitro approach [0.03%]
一种7-羟基弥兰碱富集的 kratom制剂的致遗传毒性风险评估：一种集成的计算和体外方法
Nathaphat Harnkit,Tiyanee Sahad,Ittiya Noonate et al.
Nathaphat Harnkit et al.
The increasing global use of Mitragyna speciosa (Kratom) necessitates a thorough safety assessment, particularly regarding the genotoxic potential of its key alkaloids. This study employed an integrated in silico and in vitro approach to ev...
Phytochemical composition and anti-Alzheimer potential of medicinal plants from Central and West Africa: Systematic review [0.03%]
西非和中非药用植物的植物化学成分及抗阿尔茨海默活性：系统评价
Protais Mukunzi,Ben Shalom Byishimo,Ekom Monday Etukudo et al.
Protais Mukunzi et al.
In recent time, the use of medicinal plants in the management of human disease conditions has gained immense attention. The aim of the present review was to explore the phytochemical composition and anti-Alzheimer potential of medicinal pla...
Azilsartan as a novel anti-ferriptotic agent via the upregulation of the Nrf2/HO-1/SLC7A11/GPX4 axis and downregulation of inflammatory pathways in folic acid-induced acute kidney injury in male mice [0.03%]
阿齊沙坦通过上调Nrf2/HO-1/SLC7A11/GPX4轴和下调炎症通路，作为新型防铁死亡剂用于治疗雄性小鼠叶酸诱导的急性肾损伤
Elaf Mahmood Shihab,Saba Naseer Abbas,Saja Majeed Shareef et al.
Elaf Mahmood Shihab et al.
Purpose: Azilsartan, a unique angiotensin II receptor blocker (ARB) with an oxo-oxadiazole ring, exhibits antioxidant and anti-inflammatory properties, but its role in ferroptosis-mediated AKI remains unexplored. This stu...
Toxicity and health effects of delta-8, delta-9, and delta-10-tetrahydrocannabinol and unregulated cannabinoids in vaping products [0.03%]
关于 vape 产品中毒性四氢大麻酚和无监管的大麻素的毒理学及健康效应研究：δ-8、δ-9 和 δ-10-THC 的比较
Karen Lin,Yehao Sun,Rhea Raghu et al.
Karen Lin et al.
Hemp-derived cannabinoids (CBDs) such as Δ8- and Δ10-tetrahydrocannabinol (THC) in cannabis e-cigarettes have been growing in popularity among youth, causing great concern for their health effects. Previous novel lung injury outbreaks, su...
Acute polyneuropathy associated with Kambo poisoning: An unusual case report [0.03%]
与坎博中毒相关的急性多发性神经病：一例罕见病例报告
Julio César Mantilla-Pardo,Juan David García-Valencia,Juan Pablo Fernández-Cubillos
Julio César Mantilla-Pardo
Kambo is a natural secretion obtained from the Amazonian frog Phyllomedusa bicolor, traditionally used in ritualistic and alternative medicine practices for its purported purifying and immunostimulatory effects. Acute intoxication has been ...
Prediction of primary human targets and toxicity mechanisms of imidacloprid using integrative In Silico approaches [0.03%]
基于集成计算毒理学方法的噻虫啉作用于主要人类靶标及毒性机制预测研究
Cherdsak Boonyong,Pannapa Powthong
Cherdsak Boonyong
Imidacloprid is frequently detected as a residue in food commodities, raising concerns about potential human health risks. Previous findings remain fragmented, and no study has systematically elucidated the primary human target organs and u...
Synthesis, characterization, and anticancer evaluation of N- Heterocyclic entities: ADME profiling and In Silico predictions [0.03%]
N-杂环实体的合成、表征及抗肿瘤评价：ADME特征和分子模拟预测研究
Zakariae Abbaoui,Oussama Khibech,Hüseyin Karci et al.
Zakariae Abbaoui et al.
This study aimed to synthesize a novel series of N-heterocyclic compounds and evaluate their integrated pharmacological potential by coupling in vitro selective cytotoxicity on tumor and normal cell lines with predictive in silico ADME-Tox ...