Unveiling melatonin's multifaceted actions against ferroptotic neurotoxicity in ischemic stroke [0.03%]
褪黑素对抗缺血性卒中铁死亡神经毒性的多重作用机制
Soraya Boonmag,Russel J Reiter,Piyarat Govitrapong
Soraya Boonmag
Ferroptosis, an iron-mediated form of programmed cell death, is increasingly recognized for its role in neurodegenerative diseases, with relevance to ischemic stroke, a condition that creates a permissive environment for this process. The p...
Telmisartan protects male reproductive function by modulating biochemical, oxidative stress, apoptosis, and DNA integrity in cyclophosphamide-exposed rats [0.03%]
替米沙坦通过调节生物化学、氧化应激、凋亡和DNA完整性来保护环磷酰胺暴露大鼠的雄性生殖功能
Ahmed Ageeb Kassid,Ahmed Mohammed Mahmood,Khalid Ali Obaid et al.
Ahmed Ageeb Kassid et al.
Background: Cyclophosphamide (CPA) is a common chemotherapy drug known to cause significant damage to testicular health. It induces oxidative stress, inflammation, cell death, and DNA damage. Telmisartan blocks the angiot...
The association between organophosphate pesticide residue exposure and non-alcoholic fatty liver disease: A systematic review [0.03%]
有机磷农药残留暴露与非酒精性脂肪肝疾病的相关性：系统综述
Bahare Mohamadi,Mohammadreza Tolou Ostadan,Samira Shokri et al.
Bahare Mohamadi et al.
Non-alcoholic fatty liver disease (NAFLD) is a chronic disease that has had a significant prevalence in recent decades. Various factors contribute to the disease, with diet being one of the most important. In recent decades, several studies...
Lack of genotoxicity and subchronic toxicity in safety assessment studies of a Clostridium beijerinckii formulation [0.03%]
芽孢杆菌制剂安全评估研究的遗传毒性和亚慢性毒性缺失
Esther J Yu,John Eid,Jaime Hernandez-Maldonado et al.
Esther J Yu et al.
A powder formulation of viable Clostridium beijerinckii bacteria (CBEI) was evaluated in a battery of genotoxicity studies and 14-day and 90-day repeat-dose toxicity studies in rats to evaluate CBEI as a food ingredient. All studies followe...
Direct adverse effects of fipronil sulfone, diisopentyl phthalate and disperse red 60 on zebrafish hepatocytes [0.03%]
Bianca de Arruda Leite,Danielle P de Oliveira,Suraj Unniappan
Bianca de Arruda Leite
The major concerns about emerging pollutants fipronil sulfone, disperse red 60 (DR60), and diisopentyl phthalate (DiPP) include their environmental persistence, difficulty in its removal from water sources, and bioaccumulation in aquatic or...
Rutin outperforms gallic acid in mitigating carbon tetrachloride-induced nephrotoxicity: Integrated in silico (docking, MD simulations, DFT) and in vivo mechanistic validation [0.03%]
芦丁比没食子酸在缓解四氯化碳诱导的肾毒性的研究：综合分子对接、分子动力学模拟和密度泛函理论及体内机理验证
Hend A Essa,Abdallah Ashraf,Mohamed Elsheikh
Hend A Essa
Background: Carbon tetrachloride (CCl₄) induces nephrotoxicity via oxidative stress and inflammation. Aim: This novel comparative stud...
Acute effect of tetracycline on systemic stress markers and organ histopathology in juvenile Nile tilapia, Oreochromis niloticus [0.03%]
四环素对尼罗罗非鱼急性毒性效应的研究
Md Al-Emran,Md Asad Ud Zahan Siddique,Md Sayem Sheikh et al.
Md Al-Emran et al.
Antibiotic contamination in aquaculture systems frequently encounter severe threat to aquatic life including fish. This study aimed to evaluate acute toxicological effects of tetracycline in juvenile Nile tilapia, Oreochromis niloticus. We ...
Berberine nanoemulsion against nephrotoxicity induced by bisphenol a in rats during pre-puberty stage [0.03%]
巴比妥在预防青春期前大鼠双酚A肾毒性中的作用及其机制研究
Shahnaz Rajabi,Atena Mansouri,Tahora Fakhrtaha et al.
Shahnaz Rajabi et al.
This study evaluated the effects of berberine nanoemulsion (BNE) against nephrotoxicity induced by bisphenol A (BPA), a plastic chemical, in rats during the pre-puberty stage. Thirty-six male Wistar rats (23-day-old) were randomly allocated...
Investigation of serum concentration and the type of opioid used in patients with opium poisoning [0.03%]
鸦片中毒患者血药浓度及阿片类型的研究
Armin Mansouri Sarabbadieh,Nazir Fattahi,Mohammad Mehdi Veisi et al.
Armin Mansouri Sarabbadieh et al.
Opioid poisoning constitutes a major public health issue in Iran and worldwide, with increasing rates attributed to both traditional opiates and synthetic derivatives such as methadone. Reliable assessment of serum opioid concentrations is ...
Circulating miR-126 and miR-155 are associated with environmental lead exposure: A translational approach via human biomonitoring and bioinformatic networks [0.03%]
基于环境暴露组学和生物信息学网络的外周血miR-126及miR-155与铅暴露关联性研究
Alejandra González-Bravo,Velia Verónica Rangel-Ramírez,Carlos Gabriel de la Trinidad-Chacón et al.
Alejandra González-Bravo et al.
Exposure to environmental contaminants, particularly lead (Pb), has increased due to anthropogenic activities and has been associated with epigenetic alterations, including changes in microRNA (miRNA) expression. Certain miRNAs have emerged...