Emerging multisystem disease mechanisms of e-cigarette vaping on human health [0.03%]
电子烟对人类健康多系统影响的新兴疾病机制研究
Md Mohaimenul Islam Tareq,Sreejayan Nair,Guanglong He
Md Mohaimenul Islam Tareq
Electronic cigarettes (e-cigarettes) have quickly grown from a niche smoking cessation design to a ubiquitous nicotine-delivery device, causing ever-growing debate concerning their safety and long-term health outcomes. This review criticall...
Methotrexate toxicity due to a medication dispensing error compounded by an interaction with proton pump inhibitors [0.03%]
一种药物调配错误导致的甲氨蝶呤毒副作用以及质子泵抑制剂的影响并发症病例报告
Ankita Chakrabarti,Murlidhar Pamarthi,Raman Bansal et al.
Ankita Chakrabarti et al.
Methotrexate at a low weekly dose is used for immunomodulation in autoimmune conditions such as rheumatoid arthritis and psoriasis. With an elimination half-life of a few hours, the drug is primarily cleared through the renal route. Elimina...
Assessing the hepatic and renal parameters of breast cancer patient blood samples before and after chemotherapy [0.03%]
化疗前后乳腺癌患者血液样本的肝肾参数评估
Ghaith B Heilat,Tahani Alwidyan,Amjad Z Alrosan et al.
Ghaith B Heilat et al.
Breast cancer (BC) is the most common malignancy in women, with chemotherapy as a fundamental treatment despite its potential to cause hepatotoxicity and nephrotoxicity. Although routine assessment of organ function is customary, the predic...
Study of exposure to benzene, toluene, ethylbenzene, and xylenes (BTEX) and protective effects of Gallic acid on oxidative stress on peripheral lymphocytes of workers in the paint unit of an automobile industry [0.03%]
苯、甲苯、乙苯和二甲苯(BTEX)的职业暴露对汽车制造业油漆部门工人外周淋巴细胞氧化应激的损伤及棓酸对其的保护作用研究
Enayatollah Seydi,Asghar Ghahri,Fatemeh Pasbin et al.
Enayatollah Seydi et al.
Exposure to workplace chemicals is a major concern across various industries, with serious consequences for workers' health and safety. The paint unit of the automotive industry exemplifies a workplace where hazardous chemicals are common. ...
Protective role of methylcobalamin (Vit B12) and pyridoxine (Vit B6) combination against teratogenic effects induced by lead in chick embryo [0.03%]
甲基钴胺和吡哆醇对铅致鸡胚畸形的保护作用研究
Rabia Idrees,Muhammad Ali Kanwal,Syeda Nadia Ahmad et al.
Rabia Idrees et al.
Environmental contamination through heavy metals poses significant health risks and cause detrimental effects on embryonic development of humans and animals. This study investigates the teratogenic effects induced by lead - one of poisonous...
Concomitant intake of high levels of monosodium glutamate and taurine induces adverse effects in the rat brain [0.03%]
同时摄入高水平的谷氨酸钠和牛磺酸会对大鼠大脑产生不利影响
Yasemin Atici,Makbule Beyza Sen,Atakan Saglam et al.
Yasemin Atici et al.
A common food additive, monosodium glutamate (MSG), is a source of glutamate, the primary excitatory neurotransmitter in the central nervous system, and has been associated with neuronal damage at high levels. Taurine (TAU), a naturally occ...
Toxicokinetics under extracorporeal clearance and temporal dissociation of hepatotoxicity and coagulopathy in ACDMB poisoning: Two index cases [0.03%]
吸附性血液灌流致急性中毒患者体内毒物动力学变化及肝毒性和凝血功能障碍的时间分离：2例报道
Kefeng Jin,Peng Wang,Xiuqin Yang et al.
Kefeng Jin et al.
Background: 2-Amino-5-chloro-N,3-dimethylbenzamide (ACDMB), a synthetic intermediate for the insecticide chlorantraniliprole, causes extremely rare occupational poisoning (six cases worldwide) with unknown human toxicokin...
Integrated LC-MS/MS profiling, network pharmacology, molecular docking, and enzyme inhibition assays reveal the antidiabetic potential of Mitragyna speciosa [0.03%]
综合LC-MS/MS分析、网络药理学、分子对接和酶抑制实验揭示了碎骨风的降糖潜力
Entris Sutrisno,Khoirunnisa Muslimawati,Jajang Japar Sodik et al.
Entris Sutrisno et al.
Mitragyna speciosa has gained attention as a medicinal plant with potential metabolic benefits, yet its antidiabetic mechanism remains unclear. This study characterized the metabolite profile of Mitragyna speciosa and explored its potential...
Favorable outcome in a neonate with methamphetamine, tobacco, and alcohol exposure with Hypoxic Ischemic Encephalopathy managed using therapeutic hypothermia [0.03%]
暴露于冰毒、烟草和酒精的新生儿缺氧缺血性脑病采用治疗性低温疗法取得良好效果
Hazel S Baconga,Carissa Paz C Dioquino
Hazel S Baconga
This report details the management of a neonate with moderate Hypoxic Ischemic Encephalopathy (HIE) and prenatal polysubstance exposure. Born at 36 weeks gestation following maternal methamphetamine, tobacco, and alcohol use, the infant suf...
Survival after severe aluminum phosphide poisoning complicated by concurrent insulin overdose: A case report [0.03%]
严重铝磷中毒并发胰岛素过量的存活个案报告
Maryam Rasouli,Rasoul Goli,Neda Mohammadi et al.
Maryam Rasouli et al.
Aluminum phosphide (ALP) poisoning remains highly lethal due to rapid cardiotoxicity, refractory hypotension, and metabolic disturbances. We report a rare case of a 31-year-old male presenting with severe hypoglycemia and decreased consciou...