Adenosine A2A receptor gene polymorphisms (ADORA2A) are associated with maximal concentric contraction pain [0.03%]
腺苷A2A受体基因多态性（ADORA2A）与最大向心收缩痛相关
Patrick J O&#x;Connor,Bryan D Loy,Jacob B Lindheimer et al.
Patrick J O&#x;Connor et al.
Objectives: To test associations of adenosine A2A receptor gene (ADORA2A) polymorphisms with maximal concentric contraction pain, caffeine-induced perceptual changes, and responses to mild eccentric injury. ...
Severity of coronavirus disease 19: Profile of inflammatory markers and ACE (rs4646994) and ACE2 (rs2285666) gene polymorphisms in Iraqi patients [0.03%]
2019冠状病毒病的严重程度：伊拉克患者的炎症标志物及ACE（rs4646994）和ACE2（rs2285666）基因多态性分布特征
Zainab S Mahmood,Hula Y Fadhil,Thaer A Abdul Hussein et al.
Zainab S Mahmood et al.
Susceptibility to coronavirus disease 2019 (COVID-19) and disease severity has recently been associated with inflammatory markers and genetic polymorphisms of ACE (angiotensin-converting enzyme) and ACE2 genes, but the evidence has been inc...
Is there any relationship between serum zinc levels and angiotensin-converting enzyme 2 gene expression in patients with coronavirus disease 2019? [0.03%]
血清锌水平和新型冠状病毒肺炎患者血管紧张素转化酶2基因表达之间是否存在相关性？
Zahra Bagheri-Hosseinabadi,Ali Pirsadeghi,Amir Rahnama et al.
Zahra Bagheri-Hosseinabadi et al.
Background: The level of angiotensin-converting enzyme 2 (ACE2) expression in different tissues is essential in the sensitivity, symptoms and consequences of COVID-19 infection. It seems that zinc is involved in the struc...
Interleukin-37 gene polymorphism and susceptibility to coronavirus disease 19 among Iraqi patients [0.03%]
伊拉克新冠肺炎患者中白细胞介素37基因多态性与易感性的研究
Aeshah A Ahmed,Ali H Ad&#x;hiah
Aeshah A Ahmed
Coronavirus disease 19 (COVID-19) is a highly contagious respiratory viral infection. Dysregulated immune response is an important feature of disease, and cytokines are among the most important mediators of dysregulated immunity. Interleuki...
MicroRNAs based regulation of cytokine regulating immune expressed genes and their transcription factors in COVID-19 [0.03%]
基于microRNA对COVID-19中细胞因子调节的免疫表达基因及其转录因子的调控研究
Manoj Khokhar,Sojit Tomo,Purvi Purohit
Manoj Khokhar
Background: Coronavirus disease 2019 is characterized by the elevation of a broad spectrum of inflammatory mediators associated with poor disease outcomes. We aimed at an in-silico analysis of regulatory microRNA and thei...
Study of rare genetic variants in TM4SF20, NFXL1, CNTNAP2, and ATP2C2 in Pakistani probands and families with language impairment [0.03%]
在巴基斯坦语障先证者及家系中研究TM4SF20、NFXL1、CNTNAP2和ATP2C2的罕见遗传变异
Erin M Andres,Heather L Neely,Huma Hafeez et al.
Erin M Andres et al.
Language impairment (LI) is highly heritable and aggregates in families. Genetic investigation of LI has revealed many chromosomal regions and genes of interest, though very few studies have focused on rare variant analysis in non-English s...
Phylogenicity of B.1.1.7 surface glycoprotein, novel distance function and first report of V90T missense mutation in SARS-CoV-2 surface glycoprotein [0.03%]
SARS-CoV-2 表面糖蛋白的谱系性、新的距离函数及表面糖蛋白中 V90T 感义突变的首次报道
Done Stojanov
Done Stojanov
Phylogenicity of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.7 surface glycoproteins reported from Europe to the National Center for Biotechnology Information (NCBI) virus database by the mid of April 2021 is analyzed...
Rapid, inexpensive methods for exploring SARS CoV-2 D614G mutation [0.03%]
探索SARS-CoV-2 D614G突变的快速且经济的方法
Sirwan M A Al-Jaf,Sherko S Niranji,Zana H Mahmood
Sirwan M A Al-Jaf
A common mutation has occurred in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), known as D614G (A23403G). There are discrepancies in the impact of this mutation on the virus's infectivity. Also, the whol...
A variant in TMPRSS2 is associated with decreased disease severity in COVID-19 [0.03%]
TMPRSS2变异体与COVID-19病情严重程度降低相关
Vishnubhotla Ravikanth,Mitnala Sasikala,Vankadari Naveen et al.
Vishnubhotla Ravikanth et al.
Background: Mortality due to COVID-19 caused by SARS-CoV-2 infection varies among populations. Functional relevance of genetic variations in Angiotensin-converting enzyme 2 (ACE2) and Transmembrane serine protease 2 (TMPR...
Design of advanced siRNA therapeutics for the treatment of COVID-19 [0.03%]
用于治疗COVID-19的先进siRNA药物的设计
Iman Niktab,Maryam Haghparast,Mohammad-Hossein Beigi et al.
Iman Niktab et al.
COVID-19 is a newly emerged viral disease that is currently affecting the whole globe. A variety of therapeutic approaches are underway to block the SARS-CoV-2 virus. Among these methods, siRNAs could be a safe and specific option, as they ...