Forging medical treatment partnerships to enhance PHC clinical trials in China [0.03%] 打造医学治疗合作关系以提升中国基层医疗卫生临床试验水平
Zhicheng Wang,Rizhen Wang,Qianyi Xia et al. Zhicheng Wang et al.
Masooma Aqeel,Karen Czischke,Ayham Daher et al. Masooma Aqeel et al.
Policy and service delivery proposals to improve primary care services in low-income and middle-income country cities [0.03%] 改善低收入和中等收入国家城市初级卫生保健服务的政策和服务传递建议
Richard J Lilford,Benjamin Daniels,Barbara McPake et al. Richard J Lilford et al.
The landscape of primary care services in low-income and middle-income country cities is diverse and dynamic, yet the quality of care received is too often low and the financial cost to the patient high. In the second Paper in this Series, ...
Q120.02024 Review The Lancet. Global health. 2025 May;13(5):e954-e966. DOI:10.1016/S2214-109X(24)00536-9 2025
Supply-side and demand-side factors affecting allopathic primary care service delivery in low-income and middle-income country cities [0.03%] 影响低收入和中等收入国家城市阿loe路径制初级保健服务提供的供方和需方因素
Richard J Lilford,Benjamin Daniels,Barbara McPake et al. Richard J Lilford et al.
Most people in low-income and middle-income countries (LMICs) now live in cities, as opposed to rural areas where access to care and provider choice is limited. Urban health-care provision is organised on very different patterns to those of...
Q120.02024 Review The Lancet. Global health. 2025 May;13(5):e942-e953. DOI:10.1016/S2214-109X(24)00535-7 2025
Personalised risk-prediction tools for cryptococcal meningitis mortality to guide treatment stratification in sub-Saharan Africa: a prognostic modelling study based on pooled analysis of two randomised controlled trials [0.03%] 基于两项随机对照试验的汇总分析制定非洲撒哈拉以南地区隐球菌性脑膜炎死亡风险预测工具,以指导治疗分层:一项预后模型研究
Thomas H A Samuels,Sile F Molloy,David S Lawrence et al. Thomas H A Samuels et al.
Background: Cryptococcal meningitis is a major driver of global HIV-related mortality, and validated approaches to stratify mortality risk could help to target effective treatment strategies. We aimed to develop and valid...
Q120.02024 Randomized Controlled Trial The Lancet. Global health. 2025 May;13(5):e920-e930. DOI:10.1016/S2214-109X(25)00010-5 2025
Fexinidazole as a new oral treatment for human African trypanosomiasis due to Trypanosoma brucei rhodesiense: a prospective, open-label, single-arm, phase 2-3, non-randomised study [0.03%] 用于治疗由罗得西亚锥虫引起的 sleeping sickness 的新口服药物 fexinidazole:一项前瞻性、开放标签、单组、II/III 期非随机临床试验
Enock Matovu,Westain Nyirenda,Anthony Eriatu et al. Enock Matovu et al.
Background: Rhodesiense human African trypanosomiasis is a neglected disease with epidemic potential that can rapidly become lethal if left untreated. The aim of this study was to show that fexinidazole could offer an alt...
Q120.02024 Clinical Trial The Lancet. Global health. 2025 May;13(5):e910-e919. DOI:10.1016/S2214-109X(25)00016-6 2025
Effectiveness and safety of fexinidazole for gambiense human African trypanosomiasis and exploration of adherence in outpatients: a phase 3b, prospective, open-label, non-randomised, cohort study [0.03%] 氟塞那达唑治疗一期和二期冈比亚锥虫病的效果和安全性以及门诊患者的依从性探索:一项III期开放标签非随机队列研究
Victor Kande Betu Kumeso,Christelle Perdrieu,Caroline Menétrey et al. Victor Kande Betu Kumeso et al.
Background: In previous clinical trials, oral fexinidazole treatment showed a favourable safety profile, while being easily administered and effective for most adult and paediatric patients with gambiense human African tr...
Q120.02024 Clinical Trial The Lancet. Global health. 2025 May;13(5):e900-e909. DOI:10.1016/S2214-109X(24)00526-6 2025
Effects and costs of a multi-component menstrual health intervention (MENISCUS) on mental health problems, educational performance, and menstrual health in Ugandan secondary schools: an open-label, school-based, cluster-randomised controlled trial [0.03%] 在乌干达中学开展的一项经期健康多成分干预(MENISCUS)对精神健康问题、教育表现和经期健康的影响及成本:一项开放标签校本群随机对照试验
Kate A Nelson,Stephen Lagony,Catherine Kansiime et al. Kate A Nelson et al.
Background: Menstrual health is a human rights issue, affecting many aspects of life including mental health, wellbeing, and education. We assessed the effectiveness and costs of a school-based, multi-component menstrual ...
Q120.02024 Randomized Controlled Trial The Lancet. Global health. 2025 May;13(5):e888-e899. DOI:10.1016/S2214-109X(25)00007-5 2025
Data gaps in prevalence rates of mental health conditions around the world: a retrospective analysis of nationally representative data [0.03%] 全球心理健康状况患病率的数据缺口:国家代表数据的回顾性分析
Caio B Casella,Antonis A Kousoulis,Brandon A Kohrt et al. Caio B Casella et al.
Background: Mental health conditions contribute substantially to the global burden of disease, affecting quality of life and leading to increased health-care expenses and mortality. Accurate data on the prevalence and cor...
Incidence rates of malaria, meningitis, and mortality in children younger than 5 years: a prospective cohort study in Ghana and Kenya before the roll-out of the RTS,S/AS01E malaria vaccine from 2016 to 2022 [0.03%] 2016年至2022年RTSS,A01E疟疾疫苗推广前的前瞻性队列研究:在加纳和肯尼亚5岁以下儿童中疟疾、脑膜炎及死亡率的发病情况
Kwaku Poku Asante,Marie-Cécile Bozonnat,Miloje Savic et al. Kwaku Poku Asante et al.
Background: The RTS,S/AS01E malaria vaccine was introduced in selected communities of Ghana, Kenya, and Malawi in 2019 under a WHO-coordinated pilot programme. The scarcity of background disease incidence rates might hamp...