How many medicinal slices should be used in an experiment of Chinese medicine extraction process? [0.03%]
中药提取工艺实验中用多少张药片合适?
Jiale Xie,Bo Chen,Jingmi Liu et al.
Jiale Xie et al.
The medicinal slice quantity for small-scale extraction experiments significantly impacts the repeatability of experimental results. A novel concept of representative mass of medicinal slices (RMMS) is presented in this work. RMMS is define...
A nanotechnology-enhanced SERS platform integrated with isothermal amplification for ultrasensitive detection of urinary miR-21 in early acute kidney injury diagnosis [0.03%]
一种集成等温扩增的SERS纳米技术平台用于尿液miR-21超灵敏检测以实现急性肾损伤的早期诊断
Liangping Fan,Wenna Liu,Qian Li et al.
Liangping Fan et al.
Acute kidney injury (AKI) remains a critical clinical condition with high morbidity and mortality, underscoring the urgent need for early and accurate diagnostic tools. Traditional biomarkers such as serum creatinine (Cr) and blood urea nit...
Iontophoresis-assisted transdermal drug delivery for the treatment of inflammatory dermatoses: A review [0.03%]
离子导入辅助经皮给药治疗炎症性皮肤病:综述
Zhixiong Wang,Xiumei Jiang,Changzhao Jiang et al.
Zhixiong Wang et al.
Inflammatory dermatoses, including psoriasis, atopic dermatitis (AD), and acne vulgaris, pose significant challenges in dermatological treatment due to the skin's natural barrier, the stratum corneum (SC), which limits the efficacy of topic...
Classification of pulmonary inflammation stages and assessment of multicomponent drug intervention based on spatiotemporal imaging variations utilizing RhB-conjugated poly-L-lysine nanoparticles [0.03%]
基于RhB偶联的聚赖氨酸纳米颗粒时空成像变化的肺部炎症分期分类及多组分药物干预评估
Man Zhang,Shanshan Zhai,He Gao et al.
Man Zhang et al.
Acute pulmonary inflammation, a major cause of morbidity and mortality, involves complex immune responses and increased vascular permeability. Conventional imaging techniques for assessing pneumonia and monitoring vascular leakage have limi...
Discovery of mitochondrial modulators using target-aggregated machine learning [0.03%]
基于目标整合机器学习的线粒体调节剂发现
Lizhuo Wang,Peng Yang,Sirui Wu et al.
Lizhuo Wang et al.
Image 1. © 2026 The Authors.
Active peptides pursuit from complicated matrices via tracing ligand-protein complex with MS/MS: Chaperone screening for lysozyme as a pilot study [0.03%]
基于质谱追踪肽-蛋白复合物主动获取复杂基质中的活性多肽:以乳酸脱氢酶伴侣筛选为例研究
Zihan Zhu,Jiahui Wen,Ting Li et al.
Zihan Zhu et al.
Image 1. © 2026 The Authors.
Therapeutic repurposing of old drugs to modulate the tumor immune microenvironment and enhance immunotherapy efficacy [0.03%]
老药新用以调节肿瘤免疫微环境和增强免疫治疗疗效
Yakai Song,Nannan Zheng,Xu Yang et al.
Yakai Song et al.
Although immunotherapy has demonstrated remarkable progress in cancer treatment, its clinical benefits remain restricted to a subset of patients and specific cancer types, primarily due to the immunosuppressive nature of the tumor microenvi...
Sweat as a diagnostic biofluid: analytical advances and future directions [0.03%]
汗水作为诊断生物流体:分析进展与未来方向
Dayanne Mozaner Bordin,Janice Irene McCauley,Eduardo Geraldo de Campos et al.
Dayanne Mozaner Bordin et al.
The use of sweat as an alternative specimen for biological analyses is well recognised and has been successfully applied in forensic toxicology and clinical health assessments. Compared to conventional matrices such as urine and blood, swea...
Potential mechanisms of natural products in improving gouty arthritis: Focusing on NLRP3 inflammasome regulation [0.03%]
天然产物通过调控NLRP3炎性小体改善痛风关节炎的潜在机制
Yunhao Yi,Yanling Chen,Wuchaonan Liu et al.
Yunhao Yi et al.
Gouty arthritis (GA) is a metabolic inflammatory disorder characterized by the deposition of monosodium urate crystals. Although conventional treatments like colchicine can relieve symptoms, they come with several limitations, such as gastr...
Drug delivery system of curcumin to the lungs based on poly(3-alloxyloxy-1,2-propylene succinate)-sebacic acid copolymers [0.03%]
基于聚[3-烷氧基氧代-1,2-丙二醇丁二酸脂]-癸二酸共聚物的输送至肺部递送姜黄素药物系统
Karolina Knap,Konrad Kwiecień,Jonasz Czajkowski et al.
Karolina Knap et al.
Polyanhydrides are attractive materials for drug delivery matrices as a result of their cytocompatibility and fast degradation rate. Here, we synthesized and characterized copolymers of poly(3-allyloxy-1,2-propylene succinate) (PSAGE) and s...