CEST MRI: Translational prospects for intervertebral disc degeneration - from basic research to clinical applications [0.03%]
CEST磁共振成像：椎间盘退变的转化前景——从基础研究到临床应用
Renchang Chen,Hao Wang,Yutong Li et al.
Renchang Chen et al.
Low back pain (LBP) caused by intervertebral disc degeneration (IVDD) is characterized by metabolic and biochemical alterations within the intervertebral disc (IVD) microenvironment. Conventional magnetic resonance imaging (MRI) is limited ...
Jie Shen,Huigen Lu,Gang Chen et al.
Jie Shen et al.
Targeting the glial-fibrotic scar microenvironment after spinal cord injury: From integrated protection to systematic regulation of regenerative balance [0.03%]
脊髓损伤后针对胶质纤维瘢痕微环境的治疗：从整体保护到再生平衡的系统调节
Zhaoliang Hou,Shenghui Shang,Haijian Sun et al.
Zhaoliang Hou et al.
Spinal cord injury (SCI) represents a severe neurological disorder characterized by complex pathophysiological cascades, frequently resulting in irreversible sensorimotor deficits. A hallmark of this condition is the dual-phase response of ...
A novel non-invasive approach monitoring skeletal stem cell function through 18F-Pentixafor PET-CT [0.03%]
一种通过18F-Pentixafor PET-CT监测骨干细胞功能的新型无创方法
Zan Li,Dongsheng Zhang,Dilibire Adili et al.
Zan Li et al.
Background: Fracture nonunion remains a major clinical challenge and is closely associated with dysfunction of osteogenic-lineage cells and their progenitors, skeletal stem cells (SSCs). However, conventional clinical app...
Role of collagen VI and IX in mechanotransduction in the cartilage microenvironments: A multiscale in silico examination [0.03%]
胶原VI和IX在软骨微环境中的机械转导作用：一种多尺度计算分析
Malek Adouni,Afif Gouissem,Yasin Y Dhaher
Malek Adouni
Background/objectives: Chondrocytes are mechanosensitive cells involved in the biosynthesis and maintenance of articular cartilage. Histologically, these cells are surrounded by a pericellular matrix (PCM) characterized b...
RhoA deficiency in chondrocyte inhibits cartilage fibrosis and ameliorates osteoarthritis progression via SOX4/MMP2 axis [0.03%]
软骨细胞中RhoA缺陷通过SOX4/MMP2轴抑制软骨纤维化并改善骨关节炎进展
Yizhou Xu,Shuyi Xu,Jiayi Li et al.
Yizhou Xu et al.
Background: Cartilage fibrosis plays a critical role in the onset and progression of osteoarthritis (OA), and although RhoA is a well-known small GTPase that regulates cytoskeletal reorganization, its role in OA progressi...
Corrigendum to "JP4-039 protects chondrocytes from ferroptosis to attenuate osteoarthritis progression by promoting Pink1/Parkin-dependent mitophagy" [J Orthop Transl 51 (2025) 132-144 / doi: 10.1016/j.jot.2025.01.001] [0.03%]
关于“JP4-039通过促进Pink1/Parkin依赖的线粒体自噬保护软骨细胞免受铁死亡，以减轻骨关节炎进展”的勘误声明[J Orthop Transl 51 (2025) 132-144 / doi: 10.1016/j.jot.2025.01.001]
Ya Xie,Zhongyang Lv,Weitong Li et al.
Ya Xie et al.
[This corrects the article DOI: 10.1016/j.jot.2025.01.001.]. © 2026 The Author(s).
Published Erratum
Journal of orthopaedic translation. 2026 May 15:59:101133. DOI:10.1016/j.jot.2026.101133 2026
Re-innervation of neuromuscular junctions by a conductive polypyrrole/silk fibroin/GelMA hydrogel facilitated functional skeletal muscle regeneration following volumetric muscle loss [0.03%]
导电聚吡咯/丝素蛋白/明胶甲基丙烯酸酯水凝胶促进体积性肌肉损失后功能型骨骼肌再生的神经重塑
Dimulati Maimaiti,Ziying He,Jinuo Liu et al.
Dimulati Maimaiti et al.
Introduction: Volumetric muscle loss (VML) is a significant clinical challenge that severely compromises patients' motor function and often results in irreversible disability. While conventional hydrogels have been explor...
Ubiquitination in intervertebral disc degeneration: from mechanisms to potential therapeutic strategies [0.03%]
泛素化在椎间盘退变中的作用：从机制到潜在治疗策略
Xuening Liu,Xuewen Kang
Xuening Liu
Intervertebral disc degeneration (IDD) is the primary cause of low back pain, imposing a heavy economic burden on individuals and society. The pathogenesis of IDD involves complex pathological processes. The interaction of extracellular mat...
Toward next-generation hip implants: From failure mechanisms to translational design [0.03%]
面向下一代人工髋关节的设计：从失效机制到临床应用
Yunhua Luo,Thomas Turgeon,Ian Polyzois
Yunhua Luo
Total hip replacement (THR) is highly successful in restoring mobility after hip fracture, yet long-term complications such as aseptic loosening, periprosthetic fracture, wear-induced osteolysis, and stress shielding continue to limit impla...