Tirzepatide and muscle composition changes in people with type 2 diabetes (SURPASS-3 MRI): a post-hoc analysis of a randomised, open-label, parallel-group, phase 3 trial [0.03%]
tirzepatide对2型糖尿病患者肌肉成分的影响(SURPASS-3 MRI):一项随机、开放标签、平行分组的三期试验的事后分析
Naveed Sattar,Ian J Neeland,Olof Dahlqvist Leinhard et al.
Naveed Sattar et al.
Background: Substantial weight reduction is often associated with loss of muscle mass. Tirzepatide has been associated with significant reductions in body weight in type 2 diabetes trials and a beneficial effect on body f...
Redifferentiation therapy in unresectable or metastatic radioactive iodine refractory thyroid cancer: an International Thyroid Oncology Group statement [0.03%]
不可切除或转移性碘难治性甲状腺癌的再分化治疗:国际甲状腺肿瘤工作组声明
Sophie Leboulleux,Laura Boucai,Naifa Busaidy et al.
Sophie Leboulleux et al.
In patients with follicular cell-derived thyroid cancer that have distant metastases and no iodine uptake, redifferentiation-ie, the restoration of tumoural 131I uptake with systemic therapy-is now possible. The use of mitogen-activated pro...
Mary Beth Weber
Mary Beth Weber
Long-term effects and effect heterogeneity of lifestyle and metformin interventions on type 2 diabetes incidence over 21 years in the US Diabetes Prevention Program randomised clinical trial [0.03%]
美国糖尿病预防计划随机临床试验中生活方式及二甲双胍干预对2型糖尿病发病的长期效应和异质性影响(长达21年)
William C Knowler,Lindsay Doherty,Sharon L Edelstein et al.
William C Knowler et al.
Background: In the US Diabetes Prevention Program (DPP), a 3-year randomised clinical trial in 3234 adults with prediabetes, type 2 diabetes incidence was reduced by 58% with intensive lifestyle intervention (ILS) and by ...
A novel diagnostic score for diagnosing arginine vasopressin deficiency (central diabetes insipidus) or primary polydipsia with basal laboratory parameters and a novel diagnostic score: results from two international multicentre prospective diagnostic studies [0.03%]
基于基础实验室参数和新型诊断评分诊断血管加压素缺乏(中枢性尿崩症)或原发性多饮的新型诊断评分及两项国际前瞻性诊断多中心研究结果
Cihan Atila,Irina Chifu,Juliana B Drummond et al.
Cihan Atila et al.
Background: Distinguishing arginine vasopressin deficiency (central diabetes insipidus) from primary polydipsia is challenging. There is no validated initial laboratory assessment or diagnostic score to rule-in or rule-ou...
Kay Weng Choy,Cherie Chiang
Kay Weng Choy
Michael Kachmar,Vance L Albaugh,Shengping Yang et al.
Michael Kachmar et al.