Mesut Savas,Susanne Kuckuck,Mariëtte R Boon et al.
Mesut Savas et al.
Obesity is increasingly managed with medications as disease-modifying therapies, reflecting its role as a gateway disease driving metabolic, cardiovascular, reproductive, neuropsychiatric, and mechanical conditions. This Review synthesises ...
Effects of a 6-week subcutaneous infusion of native GIP alone or as add-on to semaglutide in people with type 2 diabetes: a single-centre, double-blind, parallel-group, randomised, placebo-controlled trial [0.03%]
为期6周原生GIP亚皮下输注或作为索马鲁肽添加治疗对2型糖尿病患者的效果：一项单中心、双盲、平行分组、安慰剂对照的随机试验
Mads M Helsted,Christiane Fonnesbech-Wulff,Nina L Schaltz et al.
Mads M Helsted et al.
Background: The long-term glycaemic effects of glucose-dependent insulinotropic polypeptide (GIP) remain unclear. We aimed to assess whether a 6-week subcutaneous infusion of GIP alone and in combination with the GLP-1 re...
Type 1 diabetes intervention clusters in resource-limited settings: a systematic review and economic evaluation [0.03%]
资源有限条件下的一型糖尿病干预措施：系统评价与经济性分析
Sanjay Basu,Jessica Hanae Zafra-Tanaka,David Beran
Sanjay Basu
Background: Over 9 million people are living with type 1 diabetes globally, with a disproportionate burden in resource-limited settings where access to care remains constrained. Individual interventions have shown modest ...
Faidon Magkos,Norbert Stefan
Faidon Magkos
Worldwide, approximately half of the general population is actively attempting to lose weight. However, weight loss is typically followed by substantial weight regain, often leading to repeated cycles of loss and gain of bodyweight. Weight ...
Michael G Ziegler
Michael G Ziegler
Safety of biopsy in phaeochromocytoma and paraganglioma: an international, multicentre, retrospective cohort study [0.03%]
嗜铬细胞瘤和副神经节瘤活检的安全性研究：一项国际多中心回顾性队列研究
Liang Zhang,Gautier Tisserand,Yanting Shen et al.
Liang Zhang et al.
Background: Biopsy of phaeochromocytomas and paragangliomas (PPGLs) is discouraged due to the perceived risk of catecholamine-related complications. However, a systematic review showed that this recommendation is primaril...
Janaka Karalliedde
Janaka Karalliedde
Rethinking prophylactic central neck dissection in clinically node-negative papillary thyroid cancer [0.03%]
临床乳头状甲状腺癌无病灶淋巴结患者的预防性中央区颈清扫术再思考
Dana M Hartl,Martin Schlumberger
Dana M Hartl
Papillary thyroid cancer is associated with a high rate of lymph node metastases, mainly in the form of small metastases in the central compartment. Even when present, these metastases are most often undetected by preoperative ultrasound (c...
A comparison of the effects of tirzepatide and dulaglutide on major kidney events in people with type 2 diabetes: pre-specified exploratory analyses of the SURPASS-CVOT trial [0.03%]
司美格鲁肽和杜拉泰肽对2型糖尿病患者主要肾脏事件影响的比较：SURPASS-CVOT试验的事先规定探索性分析结果
Sophia Zoungas,David D&#x;Alessio,Imre Pavo et al.
Sophia Zoungas et al.
Background: In the SURPASS-CVOT trial, tirzepatide, a dual incretin agonist that targets the glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors, was shown to be non-inferior to dulaglutide ...