Bone health in adults with obesity before and after interventions to promote weight loss [0.03%]
肥胖成年人在促进体重减轻干预措施前后的骨骼健康状况
Julien Paccou,Juliet E Compston
Julien Paccou
Obesity and its associated comorbidities constitute a serious and growing public health burden. Fractures affect a substantial proportion of people with obesity and result from reduced bone strength relative to increased mechanical loading,...
Roy Taylor
Roy Taylor
Type 2 diabetes has long been thought to have heterogenous causes, even though epidemiological studies uniformly show a tight relationship with overnutrition. The twin cycle hypothesis postulated that interaction of self-reinforcing cycles ...
Francesco M Galassi,Laura Landini,Kristina Killgrove et al.
Francesco M Galassi et al.
The Lancet Diabetes Endocrinology
The Lancet Diabetes Endocrinology
Talha Burki
Talha Burki
Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C collaborative meta-analysis of randomised controlled trials [0.03%]
钠葡萄糖共转运体-2抑制剂与胰高血糖素样肽-1受体激动剂联合使用的效果和安全性：SMART-C合作meta分析的随机对照试验结果
Ellen M Apperloo,Brendon L Neuen,Robert A Fletcher et al.
Ellen M Apperloo et al.
Background: SGLT2 inhibitors and GLP-1 receptor agonists both improve cardiovascular and kidney outcomes in patients with type 2 diabetes. We sought to evaluate whether the benefits of SGLT2 inhibitors are consistent in p...
SGLT2 inhibitors and GLP-1 receptor agonists: the definitive combination? [0.03%]
SGLT2抑制剂与GLP-1受体激动剂：完美组合？
Carlos Escobar Cervantes
Carlos Escobar Cervantes
Norbert Stefan,Catarina Schiborn,Jürgen Machann et al.
Norbert Stefan et al.
Y Joseph Hwang,Todd T Brown,Jacqueline Capeau
Y Joseph Hwang
Once-weekly semaglutide in people with HIV-associated lipohypertrophy: a randomised, double-blind, placebo-controlled phase 2b single-centre clinical trial [0.03%]
塞马鲁肽治疗HIV相关脂代谢异常周制剂：一项随机、双盲、安慰剂对照的2b期单中心临床试验
Allison Ross Eckard,Qian Wu,Abdus Sattar et al.
Allison Ross Eckard et al.
Background: HIV-associated lipohypertrophy, which is characterised by an abnormal accumulation of abdominal visceral adipose tissue, remains problematic in people with HIV. Effective interventions are lacking, despite HIV...