One step closer to the end of postoperative radioactive iodine thyroid remnant ablation [0.03%]
术后放射性碘清甲治疗接近终点一步
Frederik A Verburg,Bart de Keizer
Frederik A Verburg
Thorkild I A Sørensen
Thorkild I A Sørensen
Overweight and obesity among Israeli adolescents and the risk for serious morbidity in early young adulthood: a nationwide retrospective cohort study [0.03%]
以色列青少年超重和肥胖及其早年青年期严重疾病风险的全国性回顾队列研究
Yair Zloof,Maya Nitecki,Maya Simchoni et al.
Yair Zloof et al.
Background: Morbidities related to obesity are usually associated with its severity and duration. Yet, the onset of serious morbidities in early adulthood among otherwise healthy adolescents with obesity is understudied. ...
Setmelanotide in patients aged 2-5 years with rare MC4R pathway-associated obesity (VENTURE): a 1 year, open-label, multicenter, phase 3 trial [0.03%]
针对罕见MC4R通路相关性肥胖的2～5岁患者开展的(setmelanotide药物)1年开放标签多中心3期临床试验(代码:VENTURE)
Jesús Argente,Charles F Verge,Uzoma Okorie et al.
Jesús Argente et al.
Background: Setmelanotide, a melanocortin-4 receptor (MC4R) agonist, has been shown to reduce hunger and weight in patients aged 6 years and older with proopiomelanocortin (POMC) deficiency (including biallelic variants i...
The Lancet Diabetes Endocrinology
The Lancet Diabetes Endocrinology
Setmelanotide for the treatment of severe early-childhood genetic obesity [0.03%]
setmelanotide治疗重度儿童期遗传性肥胖症
Christian L Roth
Christian L Roth
Jesús Argente,I Sadaf Farooqi,Julie A Chowen et al.
Jesús Argente et al.
Despite the diverse nature of obesity, there is compelling genetic, clinical, and experimental evidence that endorses the important contribution of brain circuits to this condition. The hypothalamus contains major regulatory circuits for bo...
Lars C Stene
Lars C Stene
Trends in the incidence of young-adult-onset diabetes by diabetes type: a multi-national population-based study from an international diabetes consortium [0.03%]
一项国际糖尿病联盟的多国基于人群的研究：不同类型青年发病糖尿病发病率的变化趋势
Dianna J Magliano,Lei Chen,Jedidiah I Morton et al.
Dianna J Magliano et al.
Background: Population-based incidence data on young-adult-onset type 1 diabetes and type 2 diabetes are limited. We aimed to examine secular trends in the incidence of diagnosed type 1 diabetes and type 2 diabetes with a...
Chantal Mathieu
Chantal Mathieu