Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial [0.03%]
在不同基线HbA1c水平下的肥胖相关射血分数保留型心力衰竭和2型糖尿病患者中semaglutide的心衰和代谢结局分析（STEP-HFpEF DM）：一项随机、双盲、安慰剂对照试验的预先指定分析
Melanie J Davies,Peter van der Meer,Subodh Verma et al.
Melanie J Davies et al.
Background: About half of patients with heart failure with mildly reduced or preserved ejection fraction (HFpEF) have type 2 diabetes. In the STEP-HFpEF DM trial of adults with obesity-related HFpEF and type 2 diabetes, s...
The Lancet Diabetes Endocrinology
The Lancet Diabetes Endocrinology
Francesco Rubino,David E Cummings,Robert H Eckel et al.
Francesco Rubino et al.
Outcomes after medical treatment for primary aldosteronism: an international consensus and analysis of treatment response in an international cohort [0.03%]
原发性醛固酮增多症的医学治疗效果：国际共识及一项国际队列研究的疗效分析
Jun Yang,Jacopo Burrello,Jessica Goi et al.
Jun Yang et al.
Background: Primary aldosteronism can be treated medically but there is no standardised method to evaluate treatment outcomes. We aimed to develop criteria for assessing the outcomes of targeted medical treatment of prima...
Halving heart failure outcomes by finerenone-mediated type 2 diabetes prevention [0.03%]
非洛地酮介导的2型糖尿病预防可使心力衰竭结局减半
Hertzel C Gerstein,Kamel Mohammedi
Hertzel C Gerstein
Sobha Sivaprasad
Sobha Sivaprasad
Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial [0.03%]
芬雷诺朗与心力衰竭患者新发糖尿病：来自FINEARTS-HF试验的预设分析
Jawad H Butt,Pardeep S Jhund,Alasdair D Henderson et al.
Jawad H Butt et al.
Background: Data on the effect of mineralocorticoid receptor antagonist therapy on HbA1c levels and new-onset diabetes are conflicting. We aimed to examine the effect of oral finerenone, compared with placebo, on incident...
Amélie Bonnefond,Jose C Florez,Ruth J F Loos et al.
Amélie Bonnefond et al.
Diabetes is a leading cause of global mortality and disability, and its economic burden is substantial. This Review focuses on type 2 diabetes, which makes up 90-95% of all diabetes cases. Type 2 diabetes involves a progressive loss of insu...