Spermatogonial stem cell transplantation into nonablated mouse recipient testes [0.03%]
非清髓小鼠睾丸的 spermatogonial 干细胞移植
Hiroko Morimoto,Narumi Ogonuki,Mito Kanatsu-Shinohara et al.
Hiroko Morimoto et al.
Spermatogonial transplantation has been used as a standard assay for spermatogonial stem cells (SSCs). After transplantation into the seminiferous tubules, SSCs transmigrate through the blood-testis barrier (BTB) between Sertoli cells and s...
Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids [0.03%]
人多能干细胞衍生器官的视网膜放射性投影扩展的模型组装
Clarisse M Fligor,Sailee S Lavekar,Jade Harkin et al.
Clarisse M Fligor et al.
The development of the visual system involves the coordination of spatial and temporal events to specify the organization of varied cell types, including the elongation of axons from retinal ganglion cells (RGCs) to post-synaptic targets in...
From development toward therapeutics, a collaborative effort on blood progenitors [0.03%]
从开发到治疗，有关血液祖细胞的协作研究
Avik Choudhuri,Tianxiao Han,Leonard I Zon
Avik Choudhuri
The National Heart, Lung, and Blood Institute Progenitor Cell Translational Consortium Blood Progenitor Meeting was hosted virtually on November 5, 2020, with 93 attendees across 20 research groups. The purpose of this meeting was to exchan...
Mesenchymal stromal cell-derived exosomes in cardiac regeneration and repair [0.03%]
心脏再生和修复中的间充质基质细胞来源的外泌体
Si-Jia Sun,Rui Wei,Fei Li et al.
Si-Jia Sun et al.
Mesenchymal stromal cell (MSC)-derived exosomes play a promising role in regenerative medicine. Their trophic and immunomodulatory potential has made them a promising candidate for cardiac regeneration and repair. Numerous studies have demo...
Unproven stem cell interventions: A global public health problem requiring global deliberation [0.03%]
未被证实的干细胞干预行为：一个全球公共卫生问题，亟需全球共同商议
Zubin Master,Kirstin R W Matthews,Mohamed Abou-El-Enein
Zubin Master
The unproven stem cell intervention (SCI) industry is a global health problem. Despite efforts of some nations, the industry continues to flourish. In this paper, we call for a global approach and the establishment of a World Health Organiz...
Extraordinary challenge, extraordinary achievement: 2020-2021 year in review [0.03%]
不凡之挑战，不凡之成绩——2020-2021年度总结
Christine Mummery
Christine Mummery
Endogenous neural stem cells modulate microglia and protect against demyelination [0.03%]
内源性神经干细胞可调节小胶质细胞并防御脱髓鞘现象
Béatrice Brousse,Océane Mercier,Karine Magalon et al.
Béatrice Brousse et al.
In response to corpus callosum (CC) demyelination, subventricular zone-derived neural progenitors (SVZdNPs) are mobilized and generate new myelinating oligodendrocytes (OLG). Here, we examine the putative immunomodulatory properties of endo...
ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts [0.03%]
人类多能干细胞及其直接分化细胞向动物受体体内移植的ISSCR指南
Insoo Hyun,Ellen Wright Clayton,Yali Cong et al.
Insoo Hyun et al.
The newly revised 2021 ISSCR Guidelines for Stem Cell Research and Clinical Translation includes scientific and ethical guidance for the transfer of human pluripotent stem cells and their direct derivatives into animal models. In this white...
Response to questioning the evidence for a Janus-faced nature of adult neurogenesis in Alzheimer's disease [0.03%]
关于质疑阿尔茨海默病成人神经发生具有两面性的证据的回应
Xiaoqing Zhang,Yufei Mei,Jing Wang et al.
Xiaoqing Zhang et al.
ISSCR's Guidelines for Stem Cell Research and Clinical Translation: Supporting development of safe and efficacious stem cell-based interventions [0.03%]
国际干细胞研究学会的干细胞研究和临床转化指南：促进安全有效的干细胞治疗的发展
Leigh Turner
Leigh Turner
The ISSCR's revised Guidelines for Stem Cell Research and Clinical Translation reflect the organization's commitment to opposing premature commercialization of stem cell-based interventions and supporting the development of products that me...