Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection [0.03%]
高效价抗逆转录病毒治疗下HIV感染的类器官模型中持续存在神经炎症和EIF2信号转导
Sean K Ryan,Michael V Gonzalez,James P Garifallou et al.
Sean K Ryan et al.
Published Erratum
Stem cell reports. 2025 Jun 4:102549. DOI:10.1016/j.stemcr.2025.102549 2025
An analysis of stem cell training programs for physicians in the US-A mirage of credibility [0.03%]
美国医师干细胞培训项目的分析——可信度的海市蜃楼
Luqman Ellythy,Mohamed Addani,Zubin Master
Luqman Ellythy
Analyzing stem cell training businesses for United States (US) physicians shows the use of sensationalized marketing language emphasizing profits and growth with many of the instructors affiliated with clinics providing unproven therapies. ...
Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells [0.03%]
NANOG增强子的发现及其在人胚胎干细胞自我更新和分化中的重要作用
Jielin Yan,Renhe Luo,Bess P Rosen et al.
Jielin Yan et al.
Human embryonic stem cells (hESCs) are notable for their ability to self-renew and to differentiate into all tissue types in the body. NANOG is a core regulator of hESC identity, and dynamic control of its expression is crucial to maintain ...
Patient-specific and gene-corrected induced pluripotent stem cell-derived endothelial cells elucidate single-cell phenotype of pulmonary veno-occlusive disease [0.03%]
基于诱导多能干细胞的患者特异性及基因修正型内皮细胞揭示肺静脉闭塞病单细胞表型
Baihui Ma,Tianjiao Li,Wenke Li et al.
Baihui Ma et al.
Published Erratum
Stem cell reports. 2025 May 28:102540. DOI:10.1016/j.stemcr.2025.102540 2025
Rebecca Z Weber,Ruslan Rust,Christian Tackenberg
Rebecca Z Weber
The human brain has a very limited capacity for self-repair, presenting significant challenges in recovery following injuries such as ischemic stroke. Stem cell-based therapies have emerged as promising strategies to enhance post-stroke rec...
Characterization and lineage tracing of a mouse adipose depot reveal properties conserved with human supraclavicular brown adipose tissue [0.03%]
小鼠脂肪库的特征和世系追踪揭示了与人类肩胛骨上棕色脂肪组织具有的属性保守性
Liang Li,Brian J Feldman
Liang Li
Enhancing energy utilization by increasing the number or activity of beige adipocytes has the potential to be of therapeutic benefit for a broad range of metabolic disorders. However, knowledge gaps in our understanding of the mouse versus ...
A zinc finger-dependent, PRDM13-driven mechanism regulates retinal progenitor cell fate from mouse embryonic stem cells via WNT signaling [0.03%]
一种锌指依赖的、由PRDM13驱动的机制通过Wnt信号通路调控小鼠胚胎干细胞向视网膜祖细胞分化
Brian W Basinski,Yuanhao Huang,Qiang Li et al.
Brian W Basinski et al.
The transcriptional regulation underlying eye field (retinal primordium) development requires precise control, yet the mechanisms guiding lineage-specific differentiation within the central nervous system (CNS) remain incompletely understoo...
Amanda Ya,Chenhui Deng,Kristina M Godek
Amanda Ya
Human pluripotent stem cells (hPSCs) maintain diploid populations for generations despite frequent mitotic errors that cause aneuploidy or chromosome imbalances. Consequently, aneuploid hPSC propagation must be prevented to sustain genome s...
Dusko Ilic
Dusko Ilic
The recent creation of dire wolf-like canids by Colossal Biosciences marks a technical achievement in genome editing and synthetic embryology. But the project also demands a reevaluation of what we mean by "de-extinction"-and whether a phen...
Tomomi Aoyagi,Takeshi Goya,Koji Imoto et al.
Tomomi Aoyagi et al.
The liver has a robust regenerative capacity. However, the mechanisms underlying this process remain unclear. Numerous studies on liver regeneration have been previously conducted using partial hepatectomy models, which may not fully repres...