Development of a platform to investigate long-term potentiation in human iPSC-derived neuronal networks [0.03%]
研究人iPSC来源的神经网络中长时程增强的平台开发
Deborah Pré,Alexander T Wooten,Steven Biesmans et al.
Deborah Pré et al.
Published Erratum
Stem cell reports. 2023 Jan 10;18(1):412. DOI:10.1016/j.stemcr.2022.12.011 2023
Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes [0.03%]
MAPK和PI3K/AKT通路的双重抑制可促进人类iPSC来源的心肌细胞成熟
Bayardo I Garay,Sophie Givens,Phablo Abreu et al.
Bayardo I Garay et al.
Published Erratum
Stem cell reports. 2023 Jan 10;18(1):411. DOI:10.1016/j.stemcr.2022.12.010 2023
Androgen Maintains Intestinal Homeostasis by Inhibiting BMP Signaling via Intestinal Stromal Cells [0.03%]
雄激素通过肠道基质细胞抑制BMP信号传导维持肠道稳态
Xin Yu,Shiguang Li,Yiming Xu et al.
Xin Yu et al.
Published Erratum
Stem cell reports. 2023 Jan 10;18(1):410. DOI:10.1016/j.stemcr.2022.11.022 2023
Ben D MacArthur
Ben D MacArthur
Stem cell biologists are increasingly making use of computational models to decipher their data. However, there is sometimes uncertainty about what makes a "good" model. The purpose of this commentary is to argue for closer integration of e...
Alaina Cockerell,Liam Wright,Anish Dattani et al.
Alaina Cockerell et al.
Embryo development is a critical and fascinating stage in the life cycle of many organisms. Despite decades of research, the earliest stages of mammalian embryogenesis are still poorly understood, caused by a scarcity of high-resolution spa...
Comprehensive characterization of fetal and mature retinal cell identity to assess the fidelity of retinal organoids [0.03%]
视网膜细胞身份的全面特征描述以评估视网膜器官的准确性
Hani Jieun Kim,Michelle O&#x;Hara-Wright,Daniel Kim et al.
Hani Jieun Kim et al.
Characterizing cell identity in complex tissues such as the human retina is essential for studying its development and disease. While retinal organoids derived from pluripotent stem cells have been widely used to model development and disea...
Single-cell multi-omics and lineage tracing to dissect cell fate decision-making [0.03%]
单细胞多组学和谱系追踪以解析细胞命运决策过程
Laleh Haghverdi,Leif S Ludwig
Laleh Haghverdi
The concept of cell fate relates to the future identity of a cell, and its daughters, which is obtained via cell differentiation and division. Understanding, predicting, and manipulating cell fate has been a long-sought goal of developmenta...
A conversation with ChatGPT on the role of computational systems biology in stem cell research [0.03%]
关于计算系统生物学在干细胞研究中的作用与ChatGPT的对话
Patrick Cahan,Barbara Treutlein
Patrick Cahan
Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model [0.03%]
fractalkine增强脱髓鞘小鼠模型中的寡树突细胞再生和少突胶质细胞重建髓鞘
Monique M A de Almeida,Adrianne E S Watson,Sana Bibi et al.
Monique M A de Almeida et al.
Demyelinating disorders of the central nervous system (CNS) occur when myelin and oligodendrocytes are damaged or lost. Remyelination and regeneration of oligodendrocytes can be achieved from endogenous oligodendrocyte precursor cells (OPCs...
Generation of innervated cochlear organoid recapitulates early development of auditory unit [0.03%]
再生听觉位点早期发育的受神经支配的耳蜗类器官生成方法
Mingyu Xia,Jiaoyao Ma,Mingxuan Wu et al.
Mingyu Xia et al.
Functional cochlear hair cells (HCs) innervated by spiral ganglion neurons (SGNs) are essential for hearing, whereas robust models that recapitulate the peripheral auditory circuity are still lacking. Here, we developed cochlear organoids w...