Mapping brain tumor microstructure: A multimodal study of diffusion MRI, intraoperative fluorescence, and neuropathology in navigated biopsies [0.03%]
基于导航活检的弥散MRI、术中荧光和神经病理学的脑肿瘤微结构研究
Elisabeth Klint,Johan Richter,Teresa Nordin et al.
Elisabeth Klint et al.
High-grade glioma characteristics such as heterogeneity and diffuse growth present a major diagnostic and therapeutic challenge, making accurate imaging essential for diagnosis and surgical planning. Diffusion MRI (dMRI) shows promise in ti...
Blood-brain barrier water exchange in relation to amyloid, cognition and cerebrovascular burden [0.03%]
血脑屏障水分交换与淀粉样蛋白、认知和脑血管负担的关系
Beatriz E Padrela,Sandra Tecelão,Bjørn-Eivind Kirsebom et al.
Beatriz E Padrela et al.
Blood-brain barrier (BBB) water exchange may serve as a sensitive early biomarker for Alzheimer's disease and age-related cognitive decline. This study applied a non-invasive multi-echo arterial spin labeling (ASL) technique to measure BBB ...
Alexia Stark,Kateryna Goloshchapova,Aldo Spolaore et al.
Alexia Stark et al.
Background: Navigated transcranial magnetic stimulation (nTMS) has become a cornerstone in preoperative functional mapping for brain tumor patients. The resting motor threshold (RMT) derived from nTMS reflects motor corte...
Multimodal neural correlates of cognitive awareness in aging and Alzheimer's disease [0.03%]
多模态神经相关认知在衰老和阿尔茨海默病中的关联
Federica Cacciamani,Marion Houot,Sophie Tezenas du Montcel et al.
Federica Cacciamani et al.
Impaired cognitive awareness-anosognosia-is a core symptom of Alzheimer's disease (AD), yet its neural correlates remain poorly defined. This study examined how cognitive awareness, measured both cross-sectionally and longitudinally via sub...
Pretreatment spatial signature of contralesional cortical activation predicts therapeutic response to 1 Hz rTMS in post-stroke upper limb motor Recovery: A fNIRS-based biomarker study [0.03%]
基于fNIRS的生物标志物研究:病灶对侧皮层激活的经颅磁刺激治疗前空间特征可预测卒中后上肢运动恢复的疗效
Le Jiao,Yuanyuan Tao,Dawei Zhang et al.
Le Jiao et al.
Background: While 1 Hz repetitive transcranial magnetic stimulation (rTMS) targeting contralesional primary motor cortex (M1) shows promise for stroke recovery, individual response variability remains a critical challenge...
Brain topology alteration in Alzheimer's disease brain networks: A multi-center study [0.03%]
阿尔茨海默病脑网络拓扑改变的多中心研究
Longhao Ma,Pan Wang,Dawei Wang et al.
Longhao Ma et al.
Alterations in brain network centrality are key features of Alzheimer's disease (AD) and may offer insights into the disruption of network organization underlying cognitive decline. We introduce a novel centrality metric, DomiRank, to chara...
Distinct cortical morphometric inverse divergence changes in Parkinson's disease correlate with transcriptional expression patterns [0.03%]
帕金森病皮层形态计量学的特异性逆向差异变化与转录组表达模式相关
Ting Zou,Xuyang Wang,Xiaofei Hu et al.
Ting Zou et al.
Growing evidence shows that parkinson's disease (PD) is a heterogeneous neurodegenerative disorder associated with region-specific changes in brain anatomy. However, the genetic mechanisms underlining these abnormalities are unclear. We aim...
Sleep spindle density and morphology are resilient to post-traumatic gray matter volume loss [0.03%]
创伤后灰质体积损失不影响睡眠纺锤波密度和形态学特征
Narges Kalantari,Véronique Daneault,Hélène Blais et al.
Narges Kalantari et al.
Moderate to severe traumatic brain injury (TBI) leads to gray matter volume (GMV) loss, cognitive dysfunction, and persistent sleep-wake complaints. Given the link between GMV and sleep spindles in healthy adults and the role of spindles in...
Acute effects of a single session of multitarget continuous Theta-Burst stimulation for essential Tremor: A Randomized, Sham-Controlled trial [0.03%]
针对原发性震颤的多靶点连续θ爆发刺激急性效果:一项随机假刺激对照试验
Anling Luo,Hongyan Huang,Jiaming Feng et al.
Anling Luo et al.
Background: Current treatments for essential tremor (ET) are suboptimal. This study aims to assess the safety and acute effects of a single session, multitarget continuous theta-burst stimulation (cTBS) applied to the bil...
Brain network connectivity and dementia risk: a bidirectional Mendelian randomisation perspective [0.03%]
脑网络连接与痴呆风险:双向孟德尔随机化角度分析
Shouqiang Zhu,Xiahao Ding,Jinhua Bo et al.
Shouqiang Zhu et al.
Objective: Disruptions in resting-state functional brain networks are consistently observed in dementia, yet their underlying relationships remain incompletely understood. This study aimed to investigate potential associa...